scholarly journals Induced abortion and spontaneous fetal loss in subsequent pregnancies.

1982 ◽  
Vol 72 (6) ◽  
pp. 548-554 ◽  
Author(s):  
C S Chung ◽  
R G Smith ◽  
P G Steinhoff ◽  
M P Mi
Keyword(s):  
Fetal Loss ◽  
Induced Abortion

Induced Abortion as a Risk Factor for Subsequent Fetal Loss

Epidemiology ◽  
1996 ◽  
Vol 7 (5) ◽  
pp. 540-542 ◽  
Author(s):  
Claire Infante-Rivard ◽  
Robert Gauthier
Keyword(s):  
Risk Factor ◽  
Fetal Loss ◽  
Induced Abortion

scholarly journals Pregnancy Outcome Patterns of Medicaid-Eligible Women, 1999-2014: A National Prospective Longitudinal Study

2020 ◽  
Vol 7 ◽  
pp. 233339282094134
Author(s):  
James Studnicki ◽  
John W. Fisher ◽  
David C. Reardon ◽  
Christopher Craver ◽  
Tessa Longbons ◽  
...  
Keyword(s):  
Pregnancy Outcome ◽  
Pregnancy Outcomes ◽  
White Women ◽  
Fetal Loss ◽  
Induced Abortion ◽  
Subsequent Pregnancy ◽  
Reproductive Health Services ◽  
Prospective Longitudinal Study ◽  
Subsequent Birth ◽  
Prospective Longitudinal

Introduction: The number and outcomes of pregnancies experienced by a woman are consequential determinants of her health status. However, there is no published research comparing the patterns of subsequent pregnancy outcomes following a live birth, natural fetal loss, or induced abortion. Objectives: The objective of this study was to describe the characteristic patterns of subsequent pregnancy outcomes evolving from each of three initiating outcome events (birth, induced abortion, natural fetal loss) occurring in a Medicaid population fully insured for all reproductive health services. Methods: We identified 7,388,842 pregnancy outcomes occurring to Medicaid-eligible women in the 17 states which paid for abortion services between 1999-2014. The first known pregnancy outcome for each woman was marked as the index outcome which assigned each woman to one of three cohorts. All subsequent outcomes occurring up to the fifth known pregnancy were identified. Analyses of the three index outcome cohorts were conducted separately for all pregnancy outcomes, three age bands (<17, 17-35, 36+), and three race/ethnicity groups (Hispanic, Black, White). Results: Women with index abortions experienced more lifetime pregnancies than women with index births or natural fetal losses and were increasingly more likely to experience another pregnancy with each subsequent pregnancy. Women whose index pregnancy ended in abortion were also increasingly more likely to experience another abortion at each subsequent pregnancy. Both births and natural fetal losses were likely to result in a subsequent birth, rather than abortion. Women with natural losses were increasingly more likely to have a subsequent birth than women with an index birth. All age and racial/ethnic groups exhibited the characteristic pattern we have described for all pregnancy outcomes: abortion is associated with more subsequent pregnancies and abortions; births and fetal losses are associated with subsequent births. Other differences between groups are, however, apparent. Age is positively associated with the likelihood of a birth following an index birth, but negatively associated with the likelihood of a birth following an index abortion. Hispanic women are always more likely to have a birth and less likely to have an abortion than Black or White women, for all combinations of index outcome and the number of subsequent pregnancies. Similarly, Black women are always more likely to have an abortion and less likely to experience a birth than Hispanic or White women. Conclusion: Women experiencing repeated pregnancies and subsequent abortions following an index abortion are subjected to an increased exposure to hemorrhage and infection, the major causes of maternal mortality, and other adverse consequences resulting from multiple separation events.

The Fitness of the Human Zygote

1975 ◽  
Vol 7 (1) ◽  
pp. 1-4 ◽  
Author(s):  
William H. James
Keyword(s):  
Standard Error ◽  
Fetal Loss ◽  
Induced Abortion ◽  
Demographic Parameters ◽  
Large Standard Error ◽  
Human Zygotes

SummaryThe fitness of human zygotes depends on both biological and demographic parameters. Some of the demographic parameters are changing at present in this country and accurate estimates of them are not available but this imprecision has no great bearing on the estimate of fitness offered below.Of 100 human zygotes, now, in this country, it is estimated that embryonic and early fetal loss (before the end of the 3rd month) accounts for 44; induced abortion, 7; late fetal loss (after the 3rd month), 4; and mortality between birth and maturity, 1½. Of the remaining 43½ who reach maturity, it is estimated that 8 fail to reproduce, leaving 35½ who do reproduce.The standard error of this estimate must be large because of the large standard error of the estimate of the incidence of natural reproductive wastage from which it was derived.

scholarly journals Prophylactic Effects of Bee Venom Phospholipase A2 in Lipopolysaccharide-Induced Pregnancy Loss

Toxins ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 404 ◽  
Author(s):  
Hyunjung Baek ◽  
HyeJin Yang ◽  
Jong Hoon Lee ◽  
Na-Hoon Kang ◽  
Jinwook Lee ◽  
...  
Keyword(s):  
Mouse Model ◽  
Phospholipase A2 ◽  
Fetal Loss ◽  
Treg Cells ◽  
Induced Abortion ◽  
Bee Venom ◽  
Protective Effects ◽  
Treg Depletion ◽  
Treg Population ◽  
Embryonic Loss

Spontaneous abortion represents a common form of embryonic loss caused by early pregnancy failure. In the present study, we investigated the prophylactic effects of bee venom phospholipase A2 (bvPLA2), a regulatory T cell (Treg) inducer, on a lipopolysaccharide (LPS)-induced abortion mouse model. Fetal loss, including viable implants, the fetal resorption rate, and the fetal weight, were measured after LPS and bvPLA2 treatment. The levels of serum and tissue inflammatory cytokines were determined. To investigate the involvement of the Treg population in bvPLA2-mediated protection against fetal loss, the effect of Treg depletion was evaluated following bvPLA2 and LPS treatment. The results clearly revealed that bvPLA2 can prevent fetal loss accompanied by growth restriction in the remaining viable fetus. When the LPS-induced abortion mice were treated with bvPLA2, Treg cells were significantly increased compared with those in the non-pregnant, PBS, and LPS groups. After LPS injection, the levels of proinflammatory cytokines were markedly increased compared with those in the PBS mouse group, while bvPLA2 treatment showed significantly decreased TNF-α and IFN-γ expression compared with that in the LPS group. The protective effects of bvPLA2 treatment were not detected in Treg-depleted abortion-prone mice. These findings suggest that bvPLA2 has protective effects in the LPS-induced abortion mouse model by regulating Treg populations.

Factor V Leiden Is Associated with Repeated and Recurrent Unexplained Fetal Losses

1997 ◽  
Vol 77 (05) ◽  
pp. 0822-0824 ◽  
Author(s):  
Elvira Grandone ◽  
Maurizio Margaglione ◽  
Donatella Colaizzo ◽  
Marina d'Addedda ◽  
Giuseppe Cappucci ◽  
...  
Keyword(s):  
Protein C ◽  
Strong Association ◽  
Activated Protein C ◽  
Fetal Loss ◽  
Factor V Leiden ◽  
Factor V ◽  
Significant Difference ◽  
History Of ◽  
Fv Leiden ◽  
Caucasian Women

SummaryActivated protein C resistance (APCR) is responsible for most cases of familial thrombosis. The factor V missense mutation Arg506>Gln (FV Leiden) has been recognized as the commonest cause of this condition. Recently, it has been suggested that APCR is associated with second trimester fetal loss. We investigated the distribution of FV Leiden in a sample (n = 43) of Caucasian women with a history of two or more unexplained fetal losses. A group (n = 118) of parous women with uneventful pregnancies from the same ethnical background served as control. We found the mutation in 7 cases (16.28%) and 5 controls (4.24%; p = 0.011). A statistically significant difference between women with only early fetal loss vs those with late events (p = 0.04) was observed. Our data demonstrate a strong association between FV Leiden and fetal loss. Furthermore, they indicate that late events are more common in these patients.

A Persistent Case of Herpes Gestationis Developed in Early Pregnancy and was Prolonged after Induced Abortion

2011 ◽  
Vol 73 (6) ◽  
pp. 563-567
Author(s):  
Yoko YOKOYAMA ◽  
Emiko TAKEISHI ◽  
Satoshi NAMIE ◽  
Shunpei FUKUDA ◽  
Masataka ARAKAWA ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
Induced Abortion ◽  
Herpes Gestationis
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