scholarly journals AB136. 194. The use of clinical parameters as adjuncts to endoscopic evaluation of mural thickening on conventional computed tomography in diagnosing malignancy

2019 ◽  
Vol 3 ◽  
pp. AB136-AB136
Author(s):  
Noel Edward Donlon ◽  
Kevin Michael Barry ◽  
Iqbal Khan ◽  
Waqar Khan ◽  
Muneeb Zafar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Clinical Parameters ◽  
Endoscopic Evaluation

The Use of Clinical Parameters as Adjuncts to Endoscopic Evaluation of Mural Thickening on Conventional Computed Tomography in Diagnosing Malignancy

2021 ◽  
pp. 1-7
Author(s):  
Noel E. Donlon ◽  
Michael E. Kelly ◽  
Muneeb Zafar ◽  
Patrick A. Boland ◽  
Cian Davis ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Weight Loss ◽  
Clinical Parameters ◽  
Endoscopic Evaluation ◽  
Diagnostic Dilemma ◽  
Gastrointestinal Malignancies ◽  
Red Flag ◽  
Endoscopic Investigation ◽  
Upper Gastrointestinal

<b><i>Background:</i></b> Mural thickening (MT) on computed tomography (CT) poses a diagnostic dilemma in the absence of clear reporting guidelines. The aim of this study was to analyse CT reports, identifying patients in whom gastrointestinal wall MT was observed, and to correlate these reports with subsequent endoscopic evaluation. <b><i>Methods:</i></b> Patients with MT who had follow-up endoscopy were included in the study (<i>n</i> = 308). The cohort was subdivided into upper gastrointestinal mural thickening (UGIMT) &amp; lower gastrointestinal mural thickening (LGIMT). <b><i>Results:</i></b> In total, 55.71% (<i>n</i> = 122) of colonoscopies and 61.8% (<i>n</i> = 55) of gastroscopies were found to be normal. Haemoglobin (HB) level in combination with MT was a predictor of neoplasia in both arms (<i>p</i> = 0.04 UGIMT cohort, <i>p</i> &#x3c; 0.001 LGIMT cohort). In addition to this, age was a significant correlative parameter in both UGIMT and LGIMT cohorts (<i>p</i> = 0.003, <i>p</i> &#x3c; 0.001 respectively). Dysphagia and weight loss were associated with UGI malignancies (38 and 63% respectively) and rectal bleeding was correlative in 20% of patients with LGI malignancies. <b><i>Conclusion:</i></b> HB, advancing age, and red flag symptoms are potentially useful adjuncts to MT in predicting upper and lower gastrointestinal malignancies. We propose the adoption of a streamlined pathway to delineate patients who should undergo endoscopic investigation following CT identification of MT.

scholarly journals Computed tomography findings of bowel wall thickening: its significance and relationship to endoscopic abnormalities

2012 ◽  
Vol 94 (1) ◽  
pp. 23-27 ◽  
Author(s):  
MM Uzzaman ◽  
A Alam ◽  
MS Nair ◽  
R Borgstein ◽  
L Meleagros
Keyword(s):  
Computed Tomography ◽  
Rectal Bleeding ◽  
Transverse Colon ◽  
Bowel Wall ◽  
Malignant Lesion ◽  
Wall Thickening ◽  
Neoplastic Disease ◽  
Endoscopic Evaluation ◽  
Neoplastic Lesion ◽  
Bowel Wall Thickening

INTRODUCTION The aim of this study was to conduct retrospective analysis of abdominopelvic computed tomography (CT) reports, identifying those patients in whom bowel wall thickening (BWT) was observed, and to correlate these reports with subsequent endoscopic evaluation. METHODS Formal reports for all patients undergoing abdominopelvic CT between February 2007 and September 2009 were reviewed. Where patients were identified as having colorectal ‘wall thickening’, results of subsequent endoscopic evaluations were documented. Only those patients with a report of BWT who had follow-up endoscopy (colonoscopy, sigmoidoscopy) were included in the analysis. RESULTS A total of 165 patients were included. Abnormalities on endoscopy at the exact site of the BWT on CT were found in 95 patients (57.58%); in 36 cases (21.82%) this was a malignant lesion. BWT of the transverse colon was significantly more likely to correspond to an endoscopic finding of cancer than other sites (p=0.034). Rectal bleeding was reported significantly more often in patients with BWT and neoplastic disease on endoscopy compared with those with normal endoscopy (p=0.04). Excluding patients with inflammatory/diverticular lesions, 59.02% of Caucasians had a neoplastic lesion at the site of reported BWT, significantly higher than the other ethnic groups (p=0.008). There were 38 patients (23.03%) who did not present with bowel symptoms and, of these, 6 were diagnosed subsequently with colorectal cancer. CONCLUSIONS This study supports endoscopic evaluation to investigate patients with CT evidence of BWT, especially in cases involving the transverse colon, in Caucasian patients or in association with symptoms of rectal bleeding.

scholarly journals Predicting the Amount of Intraperitoneal Fluid Accumulation by Computed Tomography and Its Clinical Use in Patients With Perforated Peptic Ulcer

2014 ◽  
Vol 99 (6) ◽  
pp. 824-829 ◽  
Author(s):  
Toru Ishiguro ◽  
Youichi Kumagai ◽  
Hiroyuki Baba ◽  
Yusuke Tajima ◽  
Hideko Imaizumi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Peptic Ulcer ◽  
Postoperative Complications ◽  
Ct Scan ◽  
Peritoneal Fluid ◽  
Treatment Decision ◽  
Perforated Peptic Ulcer ◽  
Clinical Parameters ◽  
Treatment Decision Making ◽  
The Relationship

Abstract The correlation between the amount of peritoneal fluid and clinical parameters in patients with perforated peptic ulcer (PPU) has not been investigated. The authors' objective was to derive a reliable formula for determining the amount of peritoneal fluid in patients with PPU before surgery, and to evaluate the correlation between the estimated amount of peritoneal fluid and clinical parameters. We investigated 62 consecutive patients who underwent emergency surgery for PPU, and in whom prediction of the amount of accumulated intraperitoneal fluid was possible by computed tomography (CT) using the methods described by Oriuchi et al. We examined the relationship between the predicted amount of accumulated intraperitoneal fluid and that measured during surgery, and the relationship between the amount of fluid predicted preoperatively or measured during surgery and several clinical parameters. There was a significant positive correlation between the amount of fluid predicted by CT scan and that measured during surgery. When patients with gastric ulcer and duodenal ulcer were analyzed collectively, the predicted amount of intraperitoneal fluid and the amount measured during surgery were each associated with the period from onset until CT scan, perforation size, the Mannheim peritoneal index, and the severity of postoperative complications according to the Clavien–Dindo classification. Our present results suggest that the method of Oriuchi et al is useful for predicting the amount of accumulated intraperitoneal fluid in patients with PPU, and that this would be potentially helpful for treatment decision-making and estimating the severity of postoperative complications.

scholarly journals Primary Malignant Melanoma of the Genitourinary Tract with Upper and Lower Tracts Involvement

2013 ◽  
Vol 2013 ◽  
pp. 1-2
Author(s):  
Broderick Sutton ◽  
Robert Chan ◽  
Mark Sutton ◽  
Timothy Boone
Keyword(s):  
Computed Tomography ◽  
Malignant Melanoma ◽  
Transition Point ◽  
Primary Malignant Melanoma ◽  
Shortness Of Breath ◽  
Endoscopic Evaluation ◽  
Soft Tissue Density ◽  
Computed Tomography Imaging ◽  
Genitourinary System ◽  
Tomography Imaging

A 91-year-old female presented with lower extremity swelling and shortness of breath. Laboratory analysis revealed elevations in blood urea nitrogen and creatinine along with microscopic hematuria on urinalysis. Computed tomography imaging showed moderate right hydronephrosis with dilatation of the proximal ureter with a soft tissue density at a transition point. Endoscopic evaluation revealed multiple raised, fleshy, and hemorrhagic masses throughout the bladder which are present in both ureters. Biopsy of these lesions revealed malignant melanoma invading the lamina propria. No dermatologic lesions were identified suggesting a primary malignant melanoma of the genitourinary system.

Endoscopic evaluation of the effect of sucralfate therapy and other clinical parameters on the recurrence rate of gastric ulcers

1980 ◽  
Vol 25 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Takeo Miyake ◽  
Joji Ariyoshi ◽  
Takeshi Suzaki ◽  
Masami Oishi ◽  
Masahiko Sakai ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Gastric Ulcers ◽  
Clinical Parameters ◽  
Endoscopic Evaluation

18F-choline PET/computed tomography and clinical parameters in the detection of significant prostate cancer in patients with increased prostate-specific antigen levels and previous negative biopsies

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Germán Andrés Jiménez Londoño ◽  
Ana Maria García Vicente ◽  
Edel Noriega Álvarez ◽  
Francisco José Pena Pardo ◽  
Mariano Amo-Salas ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Computed Tomography ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Clinical Parameters ◽  
Choline Pet ◽  
Negative Biopsies
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