Endoscopic evaluation of the effect of sucralfate therapy and other clinical parameters on the recurrence rate of gastric ulcers

1980 ◽  
Vol 25 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Takeo Miyake ◽  
Joji Ariyoshi ◽  
Takeshi Suzaki ◽  
Masami Oishi ◽  
Masahiko Sakai ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Gastric Ulcers ◽  
Clinical Parameters ◽  
Endoscopic Evaluation

The location and size of gastric ulcers: radiologic and endoscopic evaluation

1984 ◽  
Vol 143 (4) ◽  
pp. 755-758 ◽  
Author(s):  
DW Gelfand ◽  
WJ Dale ◽  
DJ Ott
Keyword(s):  
Gastric Ulcers ◽  
Endoscopic Evaluation

scholarly journals AB136. 194. The use of clinical parameters as adjuncts to endoscopic evaluation of mural thickening on conventional computed tomography in diagnosing malignancy

2019 ◽  
Vol 3 ◽  
pp. AB136-AB136
Author(s):  
Noel Edward Donlon ◽  
Kevin Michael Barry ◽  
Iqbal Khan ◽  
Waqar Khan ◽  
Muneeb Zafar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Clinical Parameters ◽  
Endoscopic Evaluation

The Use of Clinical Parameters as Adjuncts to Endoscopic Evaluation of Mural Thickening on Conventional Computed Tomography in Diagnosing Malignancy

2021 ◽  
pp. 1-7
Author(s):  
Noel E. Donlon ◽  
Michael E. Kelly ◽  
Muneeb Zafar ◽  
Patrick A. Boland ◽  
Cian Davis ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Weight Loss ◽  
Clinical Parameters ◽  
Endoscopic Evaluation ◽  
Diagnostic Dilemma ◽  
Gastrointestinal Malignancies ◽  
Red Flag ◽  
Endoscopic Investigation ◽  
Upper Gastrointestinal

<b><i>Background:</i></b> Mural thickening (MT) on computed tomography (CT) poses a diagnostic dilemma in the absence of clear reporting guidelines. The aim of this study was to analyse CT reports, identifying patients in whom gastrointestinal wall MT was observed, and to correlate these reports with subsequent endoscopic evaluation. <b><i>Methods:</i></b> Patients with MT who had follow-up endoscopy were included in the study (<i>n</i> = 308). The cohort was subdivided into upper gastrointestinal mural thickening (UGIMT) &amp; lower gastrointestinal mural thickening (LGIMT). <b><i>Results:</i></b> In total, 55.71% (<i>n</i> = 122) of colonoscopies and 61.8% (<i>n</i> = 55) of gastroscopies were found to be normal. Haemoglobin (HB) level in combination with MT was a predictor of neoplasia in both arms (<i>p</i> = 0.04 UGIMT cohort, <i>p</i> &#x3c; 0.001 LGIMT cohort). In addition to this, age was a significant correlative parameter in both UGIMT and LGIMT cohorts (<i>p</i> = 0.003, <i>p</i> &#x3c; 0.001 respectively). Dysphagia and weight loss were associated with UGI malignancies (38 and 63% respectively) and rectal bleeding was correlative in 20% of patients with LGI malignancies. <b><i>Conclusion:</i></b> HB, advancing age, and red flag symptoms are potentially useful adjuncts to MT in predicting upper and lower gastrointestinal malignancies. We propose the adoption of a streamlined pathway to delineate patients who should undergo endoscopic investigation following CT identification of MT.

scholarly journals Pylorectomy and Gastroduodenostomy (Billroth I Procedure) for Obstructive Antrum Pyloric Leiomyoma in a Bitch

2016 ◽  
Vol 44 (1) ◽  
pp. 6
Author(s):  
Idalini Cima ◽  
Alex Dos Santos ◽  
Claudia Cerutti Dazzi ◽  
Tanise Policarpo Machado ◽  
Adriana Costa Da Motta ◽  
...  
Keyword(s):  
Decision Making ◽  
Smooth Muscle ◽  
Gastrointestinal Endoscopy ◽  
Gastric Ulcers ◽  
Gastric Neoplasms ◽  
Upper Gastrointestinal Endoscopy ◽  
Endoscopic Evaluation ◽  
Pyloric Obstruction ◽  
Billroth I ◽  
Upper Gastrointestinal

Background: Gastric neoplasms are uncommon in dogs, especially those affecting smooth muscle layers. Leiomyoma is a smooth muscle benign neoplasm, which requires surgical resection. Pylorectomy and gastroduodenostomy (Billroth I procedure) is the most indicated technique in cases not affecting the biliary and pancreatic tracts. Thus, the purpose of this study was to report a successful case of Billroth I procedure in a bitch presenting antrum pyloric obstructive leiomyoma. Case: A 12-year-old, non-spayed, Cocker Spaniel bitch was admitted presenting depression, hyporexia, postprandial vomiting and sparse episodes of hematemesis, for 30 days. Clinical suspicion on obstructive gastric outflow disease was established. Bloodwork (complete blood count, BUN, albumin, ALP and ALT), abdominal ultrasound and thoracic radiographs were assessed. The patient undergone upper gastrointestinal endoscopy. On endoscopic evaluation, small hemorrhagic mucosa ulcers were visualized on the gastric body, antrum and pylorus. Moreover, a sessile, ulcerated, round-shape and infiltrated antral-pyloric mass was seen. The mass was 1.5-2.0 cm in diameter and apparently involved the smooth muscle layer, causing severe pyloric obstruction. However, endoscopic evaluation of the duodenum was possible. Several biopsy samples were taken from the neoplasm and sent for histopathologic assessment. The result was not conclusive due to low quality samples. The patient had progressive worsening of obstruction episodes and required surgery. A wide-margin pylorectomy and gastroduodenostomy (Billroth I procedure) was carried out. The retrieved specimen was sent to histopathological and immunohistochemistry (IHC) assessment. Positive staining for actin and desmin confirmed smooth muscle origin of the mass and histopathological assessment confirmed leiomyoma. The patient underwent regular periodic postoperative assessments, revealing progressive clinical improvement and normal weight gain. Control upper gastrointestinal endoscopy was performed. Gastric ulcers were completely healed and gastroduodenal anastomosis was functional. The anastomotic scar tissue was sampled and revealed chronic and normal healing process. Complete healing was confirmed and the patient was discharged. Discussion: Gastric neoplasms are not common in dogs. However, severe obstruction of gastric outflow is a potential risk for complications in those cases. Upper gastrointestinal endoscopic assessment is important not only for diagnosis, but also for surgery decision making. In the current study, gastroscopy provided accurate preoperative evaluation of severity of pyloric obstruction and diagnosis of secondary gastric ulcers. Direct visualization of lesions and multiple biopsy sampling were performed. The presence of neoplasms over 2-cm in diameter indicates need for complete laparoscopic or conventional surgical resection. In this case report, open resection was carried out due to prohibitive cost of laparoscopic approach, mass dimensions and probable involvement of deeper tissue layers. In conclusion, pylorectomy and gastroduodenostomy (Billroth I procedure) was curative and provided good prognosis following resection of an antrum pyloric obstructive leiomyoma. Endoscopy was critical for both diagnosis and decision-making towards surgery for gastric outflow obstruction due to an antrum pyloric neoplasm. Histopathological and immunohistochemistry assessment confirmed neoplasm type and assured oncological safety of resection with wide margins. Keywords: gastric neoplasms, smooth muscle tumor, endoscopy, dog.

Gastric Ulcers Produced by Cisplatin

1981 ◽  
Vol 39 ◽  
pp. 582-583
Author(s):  
S.K. Aggarwal ◽  
J. San Antonio
Keyword(s):  
Electron Microscopy ◽  
Single Dose ◽  
Side Effects ◽  
Antitumor Agent ◽  
Gastric Ulcers ◽  
Enzyme Cytochemistry ◽  
Intestinal Toxicity ◽  
Ovarian Cancers ◽  
Inner Surface

Cisplatin (cis-dichlorodiammineplatinum(II)) a potent antitumor agent is now available for the treatment of testicular and ovarian cancers. It is however, not free from its serious side effects including nephrotoxicity, gastro intestinal toxicity, myelosuppression, and ototoxicity. Here we now report that the drug produces peculiar bloating of the stomach in rats and induces acute ulceration.Wistar-derived rats weighing 200-250 g were administered cisplatin(9 mg/kg) ip as a single dose in 0.15 M NaCl. After 3 days the animals were sacrificed by decapitation. The stomachs were removed, the contents analyzed for pepsin and acidity. The inner surface was examined with a dissecting microscope after a moderate stretching for ulcers. Affected areas were fixed and processed for routine electron microscopy and enzyme cytochemistry.The drug treated animals kept on food and water consistently showed bloating and lesions (Fig. 1) with a frequency of 6-70 ulcers in the rumen section of the stomachs.

Effects of antisecretory agents on anglogenesis during healing of gastric ulcers

2001 ◽  
Vol 120 (5) ◽  
pp. A148-A148 ◽  
Author(s):  
M AKIMOTO ◽  
H HASHIMOTO ◽  
A MAEDA ◽  
M SHIGEMOTO ◽  
K YAMASHITA
Keyword(s):  
Gastric Ulcers

Multiple Gastric Ulcers: Their Occurrence in Benign and Malignant Lesions

1953 ◽  
Vol 25 (2) ◽  
pp. 202-217 ◽  
Author(s):  
James A. Dolphin ◽  
Lucian A. Smith ◽  
John M. Waugh
Keyword(s):  
Gastric Ulcers ◽  
Malignant Lesions

Atheromatous Embolization: a Cause of Gastric Ulcers and Small Bowel Necrosis

1964 ◽  
Vol 47 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Nathan S. Taylor ◽  
Boris Gueft ◽  
Richard J. Lebowich
Keyword(s):  
Small Bowel ◽  
Gastric Ulcers ◽  
Bowel Necrosis ◽  
Small Bowel Necrosis

Gastroscopic Diagnosis in 273 Gastric Ulcers

1953 ◽  
Vol 24 (3) ◽  
pp. 328-338 ◽  
Author(s):  
Rudolf Schindler ◽  
Jean-Jacques Desneux
Keyword(s):  
Gastric Ulcers

The Time of Healing of Gastric Ulcers: Implications as to Therapy

1952 ◽  
Vol 20 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Frederick Steigmann ◽  
Bernard Shulman
Keyword(s):  
Gastric Ulcers
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