scholarly journals An unusual increase of D-dimer level—pylephlebitis caused by acute appendicitis

2020 ◽  
Vol 9 (6) ◽  
pp. 5-5
Author(s):  
Weiqi Wang ◽  
Siyin Chen ◽  
Wenqiang Li ◽  
Jun Qu
Keyword(s):  
Acute Appendicitis ◽  
D Dimer ◽  
Unusual Increase

Determination of Factors to Distinguish MIS-C from Acute Appendicitis in Children with Acute Abdominal Pain

2021 ◽  
Author(s):  
Müjdem Nur Azılı ◽  
Doğuş Güney ◽  
Can Ihsan Oztorun ◽  
Ahmet Ertürk ◽  
Elif Emel Erten ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Negative Predictive Value ◽  
Neutrophil Count ◽  
Predictive Value ◽  
Acute Abdominal Pain ◽  
High Grade ◽  
High Grade Fever ◽  
Suspected Appendicitis ◽  
D Dimer

Abstract Introduction The aim of this study was to make the differential diagnosis between acute appendicitis and multisystem inflammatory syndrome in children (MIS-C) for patients presenting with the complaint of acute abdominal pain (AAP) and to identify the determining factors for the diagnosis of MIS-C. Materials and Methods Eighty-one children presenting with AAP/suspected AAP were evaluated. Of these, 24 (29.6%) were included in the MIS-C group (MIS-C/g) and 57 were included in the suspected appendicitis group (S-A/g), which consisted of two subgroups: appendicitis group (A/g) and control observation group (CO/g). Results Comparing MIS-C/g, A/g, and CO/g, duration of abdominal pain (2.4, 1.5, 1.8 days), high-grade fever (38.8, 36.7, 37°C), severe vomiting, and severe diarrhea were higher in MIS-C/g. Lymphocytes count (LC) was lower, while values of C-reactive protein (CRP), ferritin, and coagulopathy were higher in MIS-C/g (p < 0.05). The optimal cutoffs for the duration of abdominal pain was 2.5 days; the duration of fever, 1.5 days; peak value of fever, 39°C; neutrophil count, 13,225 × 1,000 cell/µMoL; LC, 600 × 1,000 cell/µMoL; ferritin, 233 µg/L; and D-dimer, 16.4 mg/L (p < 0.05). The optimal cutoff for CRP was 130 mg/L (sensitivity 88.9, specificity 100%, positive predictive value 100%, NPV, negative predictive value 92.5%, p < 0.001). All patients in MIS-C/g tested positive by serology by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Conclusion The duration of abdominal pain, presence of high-grade and prolonged fever, and evaluation of hemogram in terms of high neutrophil count and low LC exhibit high sensitivity and negative predictive value for MIS-C presenting with AAP. In case of doubt, inflammatory markers such as CRP, ferritin, D-dimer, and serology for SARS-CoV-2 should be studied to confirm the diagnosis.

scholarly journals Diagnostic efficacy of serum procalcitonin, IL-6, IL-2, and D-dimer levels in an experimental acute appendicitis model

2019 ◽  
Vol 30 (7) ◽  
pp. 641-647
Author(s):  
Sebahattin Destek ◽  
◽  
Vahit Onur Gul ◽  
Mustafa Oner Mentes ◽  
Ali Fuat Cicek ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Diagnostic Efficacy ◽  
D Dimer

scholarly journals The Diagnostic Value of D-dimer, Procalcitonin and CRP in Acute Appendicitis

2012 ◽  
Vol 9 (10) ◽  
pp. 909-915 ◽  
Author(s):  
Bulent Kaya ◽  
Baris Sana ◽  
Cengiz Eris ◽  
Koray Karabulut ◽  
Orhan Bat ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Diagnostic Value ◽  
D Dimer

scholarly journals Laparoscopic appendectomy during pregnancy: hemostasiological aspects

2016 ◽  
Vol 97 (6) ◽  
pp. 823-827
Author(s):  
I I Petrashenko
Keyword(s):  
Acute Appendicitis ◽  
Pregnant Women ◽  
Blood Coagulation ◽  
Laparoscopic Appendectomy ◽  
Abdominal Cavity ◽  
Coagulation System ◽  
Laparoscopic Treatment ◽  
Clotting System ◽  
Blood Coagulation System ◽  
D Dimer

Aim. To study and evaluate changes in blood coagulation system in laparoscopic treatment of acute appendicitis in different pregnancy terms.Methods. In a conducted study сhanges in blood coagulation system were evaluated in 75 pregnant women in different gestation periods who underwent laparoscopic appendectomy. Gestational age was from 4-5 to 35-36 weeks. Interventions were performed with the use of endovideosurgical complex «Olympus» OTV-SC. The pressure of carbon dioxide in the abdominal cavity was within 10-12 mm Hg. The indicators of blood coagulation system were evaluated with the use of automatic coagulometer «Amelung Coagulometr KC 4A» (Trinity Biotech, Ireland). For the diagnosis of intravascular coagulation D-dimer level in blood plasma was evaluated with immunoturbodimetric assay with latex-test «Tina-quant а D-Dimer» («Roche Diagnostics», USA) in the system «Roche/Hitachi Сobas c 6000». Fibrinolytic activity was evaluated with the use of M.A. Kotovschikova and B.I. Kuznik’s method.Results. It was found that changes in hemostasis system during laparoscopic treatment of acute appendicitis in pregnant women indicate significant increase of blood coagulation potential, both before and after laparoscopic appendectomy. This state of blood clotting system can be regarded as adequate adaptive response to aggression, designed to reduce probable or actual bleeding.Conclusion. Hemostasiologic indices during laparoscopic treatment of acute appendicitis in pregnancy are characterized by a significant intensification of the blood coagulation potential, however activation of the regulatory mechanisms of blood coagulation during endovideosurgical intervention is within the physiological norms; these changes are minimal, and laparoscopic appendectomy is the method of choice for pregnant women in different periods of gestation.

Diagnostic accuracy and prognostic utility of D Dimer in acute appendicitis in children

2015 ◽  
Vol 175 (3) ◽  
pp. 313-320 ◽  
Author(s):  
Julie Cayrol ◽  
Maria Concepción Miguez ◽  
Gloria Guerrero ◽  
Cristina Tomatis ◽  
Isabel Simal ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Diagnostic Accuracy ◽  
Prognostic Utility ◽  
D Dimer

Can d-dimer become a new diagnostic parameter for acute appendicitis?

2009 ◽  
Vol 27 (7) ◽  
pp. 765-769 ◽  
Author(s):  
Oner Mentes ◽  
Mehmet Eryilmaz ◽  
Ali Harlak ◽  
Tahir Ozer ◽  
Mujdat Balkan ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Diagnostic Parameter ◽  
D Dimer

Angiocentric lymphoma masquerading as acute appendicitis

1999 ◽  
Vol 34 (4) ◽  
pp. 378-380 ◽  
Author(s):  
Huh ◽  
S-M Hong ◽  
Kim ◽  
B-S Kim ◽  
K-H Lee ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Angiocentric Lymphoma

D-Dimer Tests Not Predictive of VTE in Elderly

2008 ◽  
Vol 41 (10) ◽  
pp. 12-13
Author(s):  
JANE SALODOF MACNEIL
Keyword(s):  
D Dimer
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