AB107. P081. Metabolic oligosaccharide engineering of pancreatic cells: measurement of sialylation and identification of sialylated glycoproteins

2018 ◽  
Vol 1 (1) ◽  
pp. AB107-AB107
Author(s):  
Vrinda Dharmarha ◽  
Christopher Saeui ◽  
Jian Song ◽  
Hui Li ◽  
Howard Katz ◽  
...  
Keyword(s):  
Pancreatic Cells ◽  
Sialylated Glycoproteins ◽  
Metabolic Oligosaccharide Engineering

Rapid probing of sialylated glycoproteins in vitro and in vivo via metabolic oligosaccharide engineering of a minimal cyclopropene reporter

2015 ◽  
Vol 13 (13) ◽  
pp. 3911-3917 ◽  
Author(s):  
De-Cai Xiong ◽  
Jingjing Zhu ◽  
Ming-Jie Han ◽  
Hui-Xin Luo ◽  
Cong Wang ◽  
...  
Keyword(s):  
Sialylated Glycoproteins ◽  
Metabolic Oligosaccharide Engineering

A minimal and efficient cyclopropene chemical handle was identified both in vitro and in vivo.

scholarly journals Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells

2015 ◽  
Vol 12 (1) ◽  
Author(s):  
Yuan Tian ◽  
Ruben T Almaraz ◽  
Caitlin H Choi ◽  
Qing Kay Li ◽  
Christopher Saeui ◽  
...  
Keyword(s):  
Pancreatic Cells ◽  
Sialylated Glycoproteins

Structural modifications of intercellular junctions.

1978 ◽  
Vol 36 (2) ◽  
pp. 330-331
Author(s):  
J. Metz ◽  
M. Merlo ◽  
W. G. Forssmann
Keyword(s):  
Gap Junctions ◽  
Intercellular Junctions ◽  
Cell Isolation ◽  
Extrahepatic Cholestasis ◽  
Structural Modifications ◽  
Pancreatic Duct Ligation ◽  
Pancreatic Cells ◽  
Duct Ligation ◽  
Thin Sectioning ◽  
And Function

Structure and function of intercellular junctions were studied under the electronmicroscope using conventional thin sectioning and freeze-etch replicas. Alterations of tight and gap junctions were analyzed 1. of exocrine pancreatic cells under cell isolation conditions and pancreatic duct ligation and 2. of hepatocytes during extrahepatic cholestasis.During the different steps of cell isolation of exocrine pancreatic cells, gradual changes of tight and gap junctions were observed. Tight junctions, which formed belt-like structures around the apex of control acinar cells in situ, subsequently diminished, became interrupted and were concentrated into macular areas (Fig. 1). Aggregations of membrane associated particles, which looked similar to gap junctions, were intermixed within tight junctional areas (Fig. 1). These structures continously disappeared in the last stages of the isolation procedure. The intercellular junctions were finally separated without destroying the integrity of the cell membrane, which was confirmed with porcion yellow, lanthanum chloride and horse radish peroxidase.

Local Integrin Activation in Pancreatic Cells Targets Insulin Secretion to the Vasculature

2018 ◽  
Author(s):  
WannJun Gan ◽  
OanhhHoang Do ◽  
Louise Cottle ◽  
Elena Kosobrodova ◽  
Justin CooperrWhite ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Integrin Activation ◽  
Pancreatic Cells

Assessment of perfluorooctanoic acid toxicity in pancreatic cells

2021 ◽  
pp. 105077
Author(s):  
Abudayyak Mahmoud ◽  
Öztaş Ezgi ◽  
Özhan Gül
Keyword(s):  
Perfluorooctanoic Acid ◽  
Pancreatic Cells ◽  
Acid Toxicity
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