scholarly journals Focal alopecia in parietal area in adult women — assessment of usefulness of trichoscopy in making a proper diagnosis

2020 ◽  
Vol 3 (2) ◽  
pp. 86-96
Author(s):  
Dominik Mikiel ◽  
Adriana Polańska ◽  
Aleksandra Dańczak‑Pazdrowska ◽  
Ryszard Żaba ◽  
Zygmunt Adamski
Keyword(s):  
Hair Loss ◽  
Lupus Erythematosus ◽  
Diagnostic Method ◽  
Skin Surface ◽  
Control Group ◽  
Discoid Lupus Erythematosus ◽  
Adult Women ◽  
Lichen Planopilaris ◽  
Non Invasive ◽  
Parietal Area

Introduction. Focal alopecia in the parietal area is one of the types of hair loss that can be found in dermatological practice. Trichoscopy is a non-invasive and easily accessible diagnostic method widely used in scalp disorders.Aim. The aim of this study was to assess the usefulness of trichoscopy in the non-invasive diagnosis of focal hair loss in adult women.Material and Methods. The study included 40 adult women. The study group consisted of 30 patients including 10 patients with alopecia areata (AA), 10 patients with discoid lupus erythematosus (DLE) and 10 with classical form of lichen planopilaris (LPP). The control group consisted of 10 healthy volunteers. Four groups of structures observed in trichoscopic examination were evaluated: hair follicle openings, hair shafts, vessels, perifollicular and interfollicular skin surface. Results. Among patients with AA the most frequently observed trichoscopic structures were: yellow dots in 100% (10/10), broken hairs in 90% (9/10), hairs resembling exclamation marks in 90% (9/10). DLE patients most often presented white / white-pink structureless areas and prominent, interfollicular scaling in 100% (10/10) and 90% (9/10) of cases, respectively. On the other hand, in the group of patients with LPP, the most frequent findings were: fine perifollicular scaling in 100% (10/10) and linear, slightly branched vessels arranged concentrically around the follicular openings - both features observed also in 100% (10/10) of cases.Conclusion. Trichoscopy as a non-invasive diagnostic method may be helpful in differentiating non-scarring and scarring alopecia in the parietal area in women. Moreover, there are some trichoscopic features typical for AA, DLE and LPP, which allow for differentiation and facilitate the diagnosis of these entities.

Hair disorders

2018 ◽  
Author(s):  
David de Berker
Keyword(s):  
Hair Loss ◽  
Alopecia Areata ◽  
Lupus Erythematosus ◽  
Inflammatory Diseases ◽  
Whole Body ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris ◽  
Small Areas ◽  
The Family ◽  
Scalp Diseases

This chapter discusses inflammatory scalp diseases and hair shedding (telogen effluvium and pattern hair loss). Inflammatory diseases of the scalp can affect all epidermal surfaces or focus upon the follicle, with relative sparing of the interfollicular skin. Eczema and psoriasis are examples of the former; other diseases, such as lichen planopilaris or discoid lupus erythematosus, are examples of the latter. Some follicular diseases, such as the family of diseases based on alopecia areata (alopecia areata (small areas of hair loss), alopecia totalis (whole scalp), and alopecia universalis (whole body)), cause barely visible follicular inflammation which results in hair loss but no scarring. Some patients present with hair shedding or change of hair pattern as their primary complaint, with no scalp disease; this is telogen effluvium. Others present with an altered pattern of scalp hair without conspicuous shedding; this is pattern hair loss.

scholarly journals A 5-year Retrospective Study on Alopecia in a Tertiary Hospital in Southern Nigeria

2020 ◽  
Vol 8 (3) ◽  
pp. 175-182
Author(s):  
C.R. Madubuko ◽  
B.U. Okwara
Keyword(s):  
Retrospective Study ◽  
Teaching Hospital ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Tertiary Hospital ◽  
Discoid Lupus Erythematosus ◽  
Female Ratio ◽  
Benin City ◽  
The University ◽  
Étude Rétrospective

Background: Alopecia is a common condition accounting for the top ten morbidities seen in patients that present at dermatology outpatient clinics in Nigeria.Aim: This retrospective study aimed at documenting the prevalence and types of alopecia in the skin clinic at the University of Benin Teaching Hospital between December 2014 and December 2019. Methods: The medical records of all patients with alopecia attending dermatological outpatient clinic between December 2014 to December 2019 were analyzed retrospectively for this descriptive observational study. An approval for the study was obtained from the Ethics Committee of the University of Benin Teaching Hospital, Benin-city, Nigeria. The diagnosis of Hair loss was essentially clinical, confirmed where expedient with a skin biopsy. Dermatological tools like Dermoscopes were also used to boost diagnostic accuracy when necessary. The patients were also evaluated for presence of other cutaneous and systemic disorders. Results: During the 5year study period, 106 patients with hair loss (6.6%%) were observed. The youngest patient was 2months old and the oldest patient was 90years old. The males constituted 61.3% of patients observed while the females accounted for 38.7% of patients seen. The male to female ratio was 1.6:1. Discoid lupus erythematosus of the scalp, was the most common disorder 29(29.4%). Alopecia areata occurred in23(27.7%); tinea capitis in 15(14,2%); Acne keloidalis nuchae in 14(13.2%); seborrheic dermatitis10(9.4%); and folliculiltis delcavans 9(8.5%). Less commonly observed causes of alopecia included androgenetic alopecia 2(1.9%); traction alopecia 2(1.9%); lichenplanopilaris 1(0.9%) and nevus sebaceum 1(0.9%). Conclusion: There is a need for studies to further describe and proffer solutions to common causes of alopecia in our community. Keywords: Retrospective study, Alopecia, Tertiary hospital, Benin French title: Une étude rétrospective de cinq (5) ans sur l'alopécie dans un hôpital tertiaire du Sud au Nigéria Contexte général de l'étude: L'alopécie est une condition de classement courante qui explique les dix principales morbidités observées chez les patients qui se présentent dans des cliniques externes de dermatologie au Nigéria.Objectif de l'étude: Cette étude rétrospective visait à documenter la prévalence et les types d'alopécie à la clinique externe de dermatologie de l'hôpital universitaire du Bénin entre décembre 2014 et décembre 2019.Méthode de l'étude: Il s'agissait d'une étude rétrospective de patients présentant principalement une perte de cheveux. Les données ont été obtenues à partir des dossiers cliniques et des notes cliniques des patients.Résultats de l'étude: Au cours de la période d'étude de 5 ans, 106 patients sur 1 600 personnes fréquentant la clinique de la peau ont eu une perte de cheveux constituant une prévalence de 6,6%. Les patients vus étaient âgés de 2 mois à 90 ans. Plus d'hommes (61,3%) que de femmes (38,7%) ont été vus; avec un rapport de 1,6: 1. Le lupus érythémateux discoïde du cuir chevelu était le trouble le plus courant «insérer un nombre absolu» (29,4%). L'alopécie areata est survenue en «insérer le nombre absolu» 27,7%; tineacapitis en «insérer le nombre absolu» 14,2%; Acné  keloidalisnuchae en «insérer le nombre absolu» 13,2%; dermatite séborrhéique «insérer le nombre absolu» 9,4%; et folliculiltisdelcavans «insérer le nombre absolu» 8,5%. Les causes d'alopécie moins fréquemment observées comprenaient l'androgénétopécie (1,9%); alopécie de traction (1,9%); lichenplanopilaris (0,9%) et naevus sébacé (0,9%)Conclusion: Des études sont nécessaires pour décrire et proposer des solutions aux causes courantes d'alopécie dans notre communauté. Mots-clés: Alopécie, lupus érythémateux discoïde, alopéciaareata, acné keloidalisnuchae

scholarly journals Trichoscopy in common scalp alopecia: an observational study

2020 ◽  
Vol 6 (3) ◽  
pp. 361
Author(s):  
Krishnendra Varma ◽  
Ujjwal Singh ◽  
Manu Kataria
Keyword(s):  
Observational Study ◽  
Lupus Erythematosus ◽  
Seborrheic Dermatitis ◽  
Daily Practice ◽  
Common Finding ◽  
Discoid Lupus Erythematosus ◽  
Diagnostic Dilemma ◽  
Lichen Planopilaris ◽  
Medical College ◽  
One Year

<p class="abstract"><strong>Background:</strong> Many patients of alopecia are encountered in daily practice with diagnostic dilemma. Trichoscopy is a sensitive, non-invasive tool which aids in clinical diagnosis.</p><p class="abstract"><strong>Methods:</strong> An observational study performed in adult patients with alopecia attending R.D. Gardi Medical College, Ujjain, over a period of one year. Trichoscopy was performed using a Dinolite digital microscope with both polarized and non polarized modes.<strong></strong></p><p class="abstract"><strong>Results:</strong> 269 patients of alopecia (257 non cicatricial, 12 cicatricial) aged 18-50 years were enrolled. The diagnosis was made after detailed history and clinical examination. 173 (64.3%) males and 96 (35.7%) females. 45.4% patients were diagnosed to have alopecia areata in which yellow dots were the most common trichoscopic finding observed in 88.5% patients. 37.2% patients were diagnosed with androgenetic alopecia with hair diameter diversity &gt;20% observed in all the patients. 9.3% patients were diagnosed to have telogen effluvium with short vellus hair seen in 64% patients. 3.7% of the patients were diagnosed to have seborrheic dermatitis with arborizing vessels being the most common finding seen in 90% patients. 2.9% patients were diagnosed with lichen planopilaris in which loss of follicles and peritubular white casts were seen in all the cases. 0.9% patients were diagnosed to have discoid lupus erythematosus with hyperkeratotic follicular plugging seen in all the cases. Overall yellow dots were the most common trichoscopic findings seen in 61% cases.</p><p class="abstract"><strong>Conclusions:</strong> Trichoscopy is a reliable diagnostic tool in hair and scalp disorders. Hence trichoscopic evaluation should be done in every case of alopecia.  </p><p class="abstract"> </p>

scholarly journals Discoid lupus erythematosus leading to squamous cell carcinoma: a case report

2017 ◽  
Vol 3 (3) ◽  
pp. 456
Author(s):  
Dadapeer H. J. ◽  
Anupama Y. G. ◽  
Sushma D. M.
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Discoid Lupus Erythematosus ◽  
Chronic Form ◽  
Short Period ◽  
Cutaneous Lupus

<p><span>Discoid lupus erythematosus (DLE) is the most common chronic form of cutaneous lupus. It is characterised by persistent scaly, disk-like plaques on scalp, face and ears that may cause pigmentary changes, scarring and hair loss. </span><span class="apple-converted-space"><span>Squamous cell carcinoma can</span></span><span> rarely arise within a longstanding DLE plaque<span class="apple-converted-space"> </span>in the skin. It presents as an enlarging warty<span class="apple-converted-space"> </span>growth or ulcer. We report a case of squamous cell carcinoma which developed on lesion of discoid lupus erythematosus within a short period of time.</span></p>

ROLE OF DERMATOSCOPY IN CHRONIC DERMATOSES DIAGNOSIS

2020 ◽  
pp. 53-56
Author(s):  
G. S. Chekhovska
Keyword(s):  
Differential Diagnosis ◽  
Lupus Erythematosus ◽  
Skin Diseases ◽  
Seborrheic Dermatitis ◽  
Hair Follicles ◽  
Discoid Lupus Erythematosus ◽  
Non Invasive ◽  
Invasive Method ◽  
Vascular Structures

Dermatoscopy is a valuable auxiliary non−invasive method used in the diagnosis of inflammatory, parasitic and viral skin diseases. Treatment of dermatoses is based on the results of analysis of melanin, follicular−horny and vascular components. Diagnosis begins with polarized dermatoscopy and then progresses to non−polarized using immersion fluid. At dermatoscopic inspection of a psoriatic plaque the point vessels evenly distributed along all the surface (a symptom of "scattered red pepper") are noted. Eczema is characterized by focal accumulation of blood vessels in the form of dots, peeling, yellowish crusts. Examination of discoid lupus erythematosus foci often reveals individual linear or branched vessels, their location is random. Red herpes zoster is dermatoscopically characterized by vascular structures in the form of large granular horny plugs of whitish color with a pearly sheen. The most informative is dermatoscopy in the differential diagnosis of erythematous form of rosacea and seborrheic dermatitis. On the erythematous background, dilated vessels around the sebaceous hair follicles, large vascular polygons formed from vessels thicker than in healthy skin and seborrheic dermatitis are found. At inspection of the fresh centers of a sclero−atrophic lichen diffuse unstructured zones of white color with a peripheral erythematous corolla and with numerous light comedic structures on a surface are visualized. At dermatoscopy of the Little − Lassueur syndrome in follicular papules on skin gray, violet points located in the form of a circle are noted. Dermatoscopy is increasingly used in dermatology, especially in the differential diagnosis of dermatoses of inflammatory and parasitic nature.

scholarly journals A NEW METHOD OF DIAGNOSIS OF THE HIATAL HERNIA ASSOCIATED WITH GASTROESOPHAGEAL REFLUX DISEASE

2019 ◽  
Vol 72 (2) ◽  
pp. 186-188
Author(s):  
Andriy R. Stasyshyn ◽  
Mykola A. Bychkov ◽  
Solomiia V. Bychkova
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Hiatal Hernia ◽  
Reflux Disease ◽  
Diagnostic Method ◽  
Calcium Content ◽  
Control Group ◽  
Non Invasive ◽  
The Relationship

Introduction: Gastroesophageal reflux disease (GERD) is one of the most common gastroduodenal diseases. The relationship between the hiatal hernia and the GERD is established. It is advisable to develop an accessible non-invasive diagnostic method for this combined pathology. The aim of the research was to estimate measuring of calcium in patients’ saliva samples as simple non-invasive diagnostic method of GERD associated with the hiatal hernia. Materials and methods: The samples of saliva were obtained from 37 patients with hiatal hernia associated with GERD and 22 healthy volunteers. The content of calcium in saliva was measured using calcium-sensitive dye Arsenazo III by photometrical method at a wavelength of 590-650 nm. Results: It has been established that in the saliva of patients with hiatal hernia, the calcium content was increased by 100.9% compared to the control group. Such a significant increase in the level of calcium in the saliva of patients with hiatal hernia may be due to the fact that the development of this pathology is a disorder of calcium homeostasis. Conclusions: It has been found that the calcium content in the saliva of patients with hiatal hernia exceeded the norm almost twice. Thus, the determination of calcium content in saliva can be used as a simple non-invasive diagnostic marker of hiatal hernia associated with GERD.

scholarly journals Pseudopelade of Brocq: a clinico-therapeutic challenge!

2014 ◽  
Vol 11 (3) ◽  
pp. 273-275
Author(s):  
S Jain
Keyword(s):  
Lupus Erythematosus ◽  
Scalp Hair ◽  
Young Male ◽  
Clinical Syndrome ◽  
Definitive Diagnosis ◽  
Discoid Lupus Erythematosus ◽  
Pathological Features ◽  
Therapeutic Challenge ◽  
Lichen Planopilaris ◽  
Specific Disease

Pseudopelade of Brocq is a clinical syndrome comprising of scarring alopecia and fibrosis in which distinct pathological features are absent. It is not a specific disease, rather a pattern of cicatricial alopecia. However, if a definitive diagnosis of DLE (discoid lupus erythematosus), LPP (Lichen planopilaris) or any other condition can be made on the basis of clinical, histopathological or immunofluorescent features, then this term cannot be used. Here we report the case of a 20 year old young male who presented to us with complaints of loss of scalp hair for 2 years which were associated with mild itching. The condition is as such rare in prevalence and hence we report the same in view of its unique presentation. DOI: http://dx.doi.org/10.3126/hren.v11i3.9652 Health Renaissance 2013;11(3):273-275

scholarly journals Discoid Lupus Erythematosus of the Scalp in a Patient with Systemic Lupus Erythematosus: A Case Report with Complete Hair Regrowth

2021 ◽  
Vol 79 (2) ◽  
pp. 155-158
Author(s):  
Cleide Garbelini-Lima ◽  
Gabriela Evangelista de Almeida ◽  
Sidharta Quércia Gabdelha ◽  
Andrea Cavalcante de Souza ◽  
Mara Lúcia Gomes de Souza ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Early Diagnosis ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Direct Immunofluorescence ◽  
Discoid Lupus Erythematosus ◽  
Systemic Lupus ◽  
Hair Regrowth ◽  
Erythematous Plaques

Scalp involvement with hair loss is common in systemic lupus erythematosus. Discoid lupus erythematosus may cause scarring alopecia, characterized by well-delimited erythematous plaques with scales, follicular hyperkeratosis and atrophy, which is considered a trichological emergency. Early diagnosis and treatment are necessary in order to prevent permanent hair loss. We describe a 44 years’ old female patient with systemic lupus erythematosus for 4 years, with multiple areas of occipitoparietal alopecia, erythematous plaques, atrophy, scales and some bloody crusts. Trichoscopy, histopathology and direct immunofluorescence led to the diagnosis of discoid lupus erythematosus. After 9 months treatment with thalidomide there was complete hair regrowth.

scholarly journals Cutaneous manifestations and systemic correlation in patients with lupus erythematosus and its subsets: a study of 40 cases

2018 ◽  
Vol 4 (4) ◽  
pp. 479
Author(s):  
Rashmi Mahajan ◽  
Kishan Ninama ◽  
Ishan Pandya ◽  
Rajvee Patel ◽  
F. E. Bilimoria
Keyword(s):  
Hair Loss ◽  
Lupus Erythematosus ◽  
Laboratory Finding ◽  
Tertiary Care ◽  
Discoid Lupus Erythematosus ◽  
Care Hospital ◽  
Cutaneous Manifestations ◽  
Malar Rash ◽  
Abnormal Laboratory ◽  
Rowell’S Syndrome

<p class="abstract"><strong>Background:</strong> The objective was to study various dermatological manifestations and clinical and laboratory features in patients of lupus erythematosus (LE) and its subsets.</p><p class="abstract"><strong>Methods:</strong> This is a cross sectional observational study done in a tertiary care hospital in a rural setup in Piparia, Ta. Waghodiya, Dist. Vadodara, Gujarat. All the patients with clinical features of LE and its subsets were included in the study over a period of 16 months and were subjected to detailed history taking, complete cutaneous and general examination and laboratory investigations.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of the 40 cases, 22 cases were systemic lupus erythematosus (SLE), 13 cases were discoid lupus erythematosus (DLE), four cases were of Rowell’s syndrome and one case was of mixed connective tissue disorder (MCTD). 97.5% of cases had cutaneous involvement, i.e. photosensitivity (77.5%), oral ulcers, hair loss and malar rash. Systemic symptoms and abnormal laboratory parameters were present in the cases of SLE, Rowell’s syndrome and MCTD, with hematological involvement being the most common in both SLE (77%) and Rowell’s syndrome (100%) and positive anti-nuclear antibody (ANA) titer being the most common abnormal laboratory finding in both SLE (95.4%) and Rowell’s syndrome (100%). The most commonly found antibody was anti-dsDNA (64.3%) in SLE and anti SS-A (100%) in Rowell’s syndrome.</p><p class="abstract"><strong>Conclusions:</strong> Cutaneous features though occasionally subtle, are pointers to a diagnosis of SLE. Hair loss, malar rash and photosensitivity alone or in association with altered hematologic/ANA profile are the key markers of the disease activity.</p><p> </p>

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