scholarly journals Extracellular Vesicles and Circulating Nucleic Acids

2021 ◽  
Keyword(s):  
Nucleic Acids ◽  
Extracellular Vesicles ◽  
Circulating Nucleic Acids

scholarly journals Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers

Cells ◽  
2019 ◽  
Vol 8 (11) ◽  
pp. 1459 ◽  
Author(s):  
Karin-Kujundzic ◽  
Sola ◽  
Predavec ◽  
Potkonjak ◽  
Somen ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Extracellular Vesicles ◽  
Diagnostic Tools ◽  
Epigenetic Changes ◽  
Apoptotic Bodies ◽  
Diagnostic Biomarkers ◽  
Epigenetic Biomarkers ◽  
Circulating Nucleic Acids ◽  
Specific Proteins ◽  
In Pregnancy

As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders. These studies have enabled the development of various new diagnostic biomarkers, such as free circulating nucleic acids, and detection of their epigenetic changes. Recently, extracellular vesicles including exosomes, microvesicles, oncosomes, and apoptotic bodies have been recognized as powerful diagnostic tools. Extracellular vesicles carry specific proteins, lipids, DNAs, mRNAs, and miRNAs of the cells that produced them, thus reflecting the function of these cells. It is believed that exosomes, in particular, may be the optimal biomarkers of pathological pregnancies and cancers, especially those that are frequently diagnosed at an advanced stage, such as ovarian cancer. In the present review, we survey and critically appraise novel epigenetic biomarkers related to free circulating nucleic acids and extracellular vesicles, focusing especially on their status in trophoblasts (pregnancy) and neoplastic cells (cancers).

The impact of non-tumor-derived circulating nucleic acids implicates the prognosis of non-small cell lung cancer

2012 ◽  
Vol 139 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Chanida Vinayanuwattikun ◽  
Pakorn Winayanuwattikun ◽  
Poonchavist Chantranuwat ◽  
Apiwat Mutirangura ◽  
Virote Sriuranpong
Keyword(s):  
Lung Cancer ◽  
Nucleic Acids ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Circulating Nucleic Acids ◽  
The Impact

Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection

2014 ◽  
Vol 207 ◽  
pp. 133-137 ◽  
Author(s):  
Ersin Karataylı ◽  
Yasemin Çelik Altunoğlu ◽  
Senem Ceren Karataylı ◽  
Cihan Yurdaydın ◽  
A. Mithat Bozdayı
Keyword(s):  
Nucleic Acids ◽  
Real Time ◽  
Real Time Pcr ◽  
Internal Controls ◽  
Circulating Nucleic Acids ◽  
Novel Approach

scholarly journals Therapeutic Potential of Nucleic Acids when Combined with Extracellular Vesicles

2021 ◽  
Vol 12 (6) ◽  
pp. 1476
Author(s):  
Brian Jurgielewicz ◽  
Steven Stice ◽  
Yao Yao
Keyword(s):  
Nucleic Acids ◽  
Extracellular Vesicles ◽  
Therapeutic Potential

Maternal Circulating Nucleic Acids as Markers of Placental Health

2018 ◽  
pp. 333-351
Author(s):  
Francesca Gaccioli ◽  
D. Stephen Charnock-Jones ◽  
Gordon C.S. Smith
Keyword(s):  
Nucleic Acids ◽  
Circulating Nucleic Acids
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