scholarly journals Immediate-Type Systemic Hypersensitivity Reactions After the Inactivated SARS-CoV-2 Vaccine in Healthcare Workers

2021 ◽  
Author(s):  
Pamir ÇERÇİ ◽  
Anıl UÇAN
Keyword(s):  
Healthcare Workers ◽  
Hypersensitivity Reactions ◽  
Systemic Hypersensitivity

Evaluation of fosaprepitant-associated hypersensitivity reactions at a National Cancer Center

2020 ◽  
Vol 26 (6) ◽  
pp. 1369-1373 ◽  
Author(s):  
Catherine Michelle Laird ◽  
Ashley E Glode ◽  
Kerry Schwarz ◽  
Elaine T Lam ◽  
Cindy L O'Bryant
Keyword(s):  
Small Sample Size ◽  
Medication Administration ◽  
Small Sample ◽  
Patient Specific ◽  
Cancer Center ◽  
Hypersensitivity Reactions ◽  
University Of Colorado ◽  
Time Period ◽  
Systemic Hypersensitivity ◽  
The University

Introduction At our institution, an increased incidence of hypersensitivity reactions was reported following standardization of fosaprepitant as the preferred agent for the prophylaxis of chemotherapy induced nausea and vomiting (CINV) caused by highly emetogenic therapies. The purpose of this evaluation was to assess the incidence of systemic hypersensitivity reactions (HSRs) to fosaprepitant infusions compared to available literature. Methods This evaluation is a retrospective review of electronic health records of adult patients who received their first dose of fosaprepitant for CINV prophylaxis beginning January 1, 2017 through June 30, 2017 at the University of Colorado Cancer Center outpatient infusion center. Subjects were identified using medication administration reports. Individual chart reviews were performed for all patients who received fosaprepitant during the specified timeframe and had a reaction reported on the same date. Results A total of 868 patients received fosaprepitant in the outpatient infusion center during the study time period. Four patients (0.461%) had a systemic HSR attributed to fosaprepitant. Two of the reactions were reported as HSRs in the adverse reaction reporting system and two were found in provider notes during chart review. Due to the small sample size, risk factors for HSRs to fosaprepitant were not able to be determined. Conclusion The incidence of HSRs to fosaprepitant at our institution was found to be consistent with the <1% incidence currently noted in literature. Based on these findings, opportunities have been identified for education on fosaprepitant-associated HSRs, proper documentation and patient-specific precautions.

Risk factors for systemic hypersensitivity reactions after booster vaccinations with human diploid cell rabies vaccine: A nationwide prospective study

Vaccine ◽  
1993 ◽  
Vol 11 (14) ◽  
pp. 1390-1394 ◽  
Author(s):  
Daniel B. Fishbein ◽  
Kristine M. Yenne ◽  
David W. Dreesen ◽  
Carol F. Teplis ◽  
Neha Mehta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Diploid Cell ◽  
Rabies Vaccine ◽  
Hypersensitivity Reactions ◽  
Human Diploid Cell ◽  
Systemic Hypersensitivity

scholarly journals Urticarial reaction following endovascular embolization of an orbital arteriovenous malformation (AVM) with n-butyl cyanoacrylate (nBCA) glue

2017 ◽  
Vol 23 (6) ◽  
pp. 666-668 ◽  
Author(s):  
Kunal R Sinha ◽  
Gary Duckwiler ◽  
Daniel B Rootman
Keyword(s):  
Arteriovenous Malformation ◽  
Surgical Resection ◽  
Arteriovenous Malformations ◽  
Vascular Inflammation ◽  
Endovascular Embolization ◽  
Vascular Lesions ◽  
Hypersensitivity Reactions ◽  
Potential Complication ◽  
Skin Allergy ◽  
Systemic Hypersensitivity

Orbital arteriovenous malformations (AVMs) are rare vascular lesions that may be managed with endovascular embolization followed by surgical resection. Embolization is often accomplished with n-butyl-2-cyanoacrylate (nBCA), which is considered to be a safe and effective liquid occlusive agent. Localized vascular inflammation has been associated with endovascular nBCA use in histopathologic studies, but reports of systemic hypersensitivity reactions following endovascular embolization with nBCA are rare. We present a case of a 26-year-old male who developed an intermittent systemic urticarial reaction without cardiopulmonary compromise beginning four weeks after nBCA embolization of an orbital AVM. Subsequent skin allergy testing performed by an allergist confirmed hypersensitivity to nBCA glue and the patient has since been successfully managed with daily oral antihistamines. Awareness of this rare potential complication of endovascular embolization with nBCA will aid in the counseling and management of patients with AVMs.

scholarly journals 65 Characteristics of Liver Injury in Drug-induced Systemic Hypersensitivity Reactions

2012 ◽  
Vol 5 ◽  
pp. S21-S22
Author(s):  
Chan Sun Park ◽  
Taehoon Lee ◽  
Yoon Su Lee ◽  
Hyouk-Soo Kwon ◽  
Su-Jeong Kim ◽  
...  
Keyword(s):  
Liver Injury ◽  
Hypersensitivity Reactions ◽  
Drug Induced ◽  
Systemic Hypersensitivity

Localized and Systemic Hypersensitivity Reactions to Human Seminal Fluid

1982 ◽  
Vol 127 (3) ◽  
pp. 616-616
Author(s):  
L.I. Bernstein ◽  
B.E. Englander ◽  
J.S. Gallagher ◽  
P. Nathan ◽  
Z.H. Marcus
Keyword(s):  
Seminal Fluid ◽  
Hypersensitivity Reactions ◽  
Systemic Hypersensitivity
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