The Antioxidant Activity of Low Doses of Moringa Seeds (Moringa oleifera Lam.) in Hypercholesterolemic Male Rats

2018 ◽  
Author(s):  
Haddad El Rabey ◽  
Jalaluddin Khan ◽  
M Sakran ◽  
Maryam Al-Ghamdi
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Male Rats ◽  
Low Doses ◽  
Moringa Oleifera Lam

Bioaccessibility, antioxidant activity and modulation effect on gut microbiota of bioactive compounds from Moringa oleifera Lam. leaves during digestion and fermentation in vitro

2019 ◽  
Vol 10 (8) ◽  
pp. 5070-5079 ◽  
Author(s):  
Zuman Dou ◽  
Chun Chen ◽  
Xiong Fu
Keyword(s):  
Antioxidant Activity ◽  
Gut Microbiota ◽  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Modulation Effect ◽  
Gastrointestinal Digestion ◽  
Colonic Fermentation ◽  
Moringa Oleifera Lam

This study aims to investigate the bioaccessibility, bioactivity and gut microbiota modulation effect of Moringa oleifera Lam. leaves after in vitro gastrointestinal digestion and colonic fermentation.

Moringa oleifera Lam. leaf powder antioxidant activity and cytotoxicity in human primary fibroblasts

2020 ◽  
pp. 1-6
Author(s):  
Andrea C. Landázuri ◽  
Arleth Gualle ◽  
Verónica Castañeda ◽  
Emilia Morales ◽  
Andrés Caicedo ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Primary Fibroblasts ◽  
Leaf Powder ◽  
Moringa Oleifera Lam

Physicochemical characterization and antioxidant activity of decolorized Moringa oleifera Lam leaf flour

Nutrire ◽  
2017 ◽  
Vol 42 (1) ◽  
Author(s):  
A. da S. Alves ◽  
E. M. B. Teixeira ◽  
G. C. Oliveira ◽  
L. Arantes-Pereira ◽  
C. C. Oliveira ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Physicochemical Characterization ◽  
Moringa Oleifera Lam

scholarly journals Antioxidant activities and simultaneous HPLC-DAD profiling of polyphenolic compounds from Moringa oleifera Lam. Leaves grown in Bangladesh

Food Research ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 401-408
Author(s):  
K.S. Ahmed ◽  
I.A. Jahan ◽  
F. Jahan ◽  
H. Hosain
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Water Extract ◽  
Ethanol Extract ◽  
Polyphenolic Compounds ◽  
Dihydroxybenzoic Acid ◽  
High Concentration ◽  
Dry Extract ◽  
Mature Leaves ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. has been used as a traditional medicine for the treatment of several diseases. In this study, the antioxidant activity and simultaneous HPLC profiling of polyphenolic compounds in 80% ethanol and water extracts of M. oleifera tender and mature leaves available in Bangladesh were investigated. The 80% ethanol extract of M. oleifera tender leaves contained high concentration and more amount of 3,4- dihydroxybenzoic acid, (-) epicatechin and rosmarinic acid (201.32±1.94, 213.08±1.96 and 133.84±1.42 mg/100 g of dry extract, respectively) than that of mature leaves (82.55±1.09, 141.86±1.10 and 16.23±0.76 mg/100 g of dry extract, respectively). On the other hand, the water extract of M. oleifera tender leaves contained a high concentration of catechin hydrate, trans-ferulic acid and quercetin (530.05±1.91, 166.38±0.90 and 771.74±1.34 mg/100 g of dry extract, respectively) than that of mature leaves (207.21±0.90, 62.42±0.45 and 483.25±1.04 mg/100 g of dry extract, respectively). It was also found that 3,4-dihydroxybenzoic acid, catechol, p-coumaric acid and trans-cinnamic acid were detected only in 80% ethanol extract of M. oleifera leaves but syringic acid was identified in the water extract. In DPPH free radical scavenging activity test, IC50 values of 80% ethanol extract of tender leaves (EETL), 80% ethanol extract of mature leaves (EEML), water extract of tender leaves (WETL) and water extract of mature leaves (WEML) were found to be moderately significant (105.50±1.05, 115.00±1.14, 216.00±1.34 and 269.50±1.56 μg/mL, respectively) when compared to the IC50 value of ascorbic acid, 3.32±0.07 μg/mL. The polyphenolic compounds are responsible for antioxidant activity. On the basis of the present study, it can be suggested that the leaves show antioxidant activity and it’s contained a significant amount and different types of polyphenolic compounds. Standardized polyphenolic compounds from M. oleifera leaves could be used as a better source of natural antioxidant supplement.

scholarly journals Phytochemical Analyses, Antioxidant and Anticancer Activities of Ethanolic Leaf Extracts of Moringa oleifera Lam. Varieties

Plants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2348
Author(s):  
Bilques Farooq ◽  
Bhupendra Koul ◽  
Deveshi Mahant ◽  
Dhananjay Yadav
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Sugar Content ◽  
Soluble Proteins ◽  
Mature Stage ◽  
Cytotoxic Activities ◽  
Anticancer Activities ◽  
Leaf Extracts ◽  
Anticancer Compounds ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (Moringaceae) is revered as s ‘miracle tree’ due to its remarkable nutritional, medicinal and industrial uses. In our study, a comparative analysis of the nutritional parameters (antioxidant activity, sugar content—TSS, total soluble proteins—TSP and mineral contents), phytochemicals (HPLC analysis of four anticancer compounds), and cytotoxicity of M. oleifera leaf extracts (MLEs) of five selected varieties (conventional, PKM-1, PKM-2, ODC, and Jaffna), was performed. Jaffna variety possessed the highest antioxidant activity (FRAP) followed by other four varieties. The trend observed was: Jaffna (9.47 µg/mL, 18.48 µg/mL, 29.39 µg/mL, and 35.37 µg/mL) > PKM-1 (4.82 µg/mL, 7.63 µg/mL, 22.33 µg/mL, and 27.71 µg/mL) > PKM-2 (2.10 µg/mL, 7.04 µg/mL, 13.18 µg/mL, and 21.78 µg/mL) > ODC (0.17 µg/mL, 2.10 µg/mL, 4.41 µg/mL and 13.94 µg/mL) > Conventional (0.05 µg/mL, 1.08 µg/mL, 2.86 µg/mL, and 5.40 µg/mL), total soluble proteins (TSP) [0.69 ± 0.01 and 0.94 ± 0.01 µg/mL (young and mature stage, respectively)], sugar content (TSS) [0.39 ± 0.01 and 0.51 ± 0.01 µg/mL (young and mature stage, respectively)], chlorophyll content [1.07 ± 0.01 (plantlet stage), 1.36 ± 0.003 (vegetative-stage), 0.82 ± 0.004 (reproductive stage) mg/g], followed by the other four varieties. The trend observed for cytotoxic activities of ethanolic MLEs on HepG2 cell line, based on the IC50 values, was conventional (1.22 mg/mL) > ODC (0.90 mg/mL) > PKM-2 (0.65 mg/mL) > PKM-1 (0.35 mg/mL) > Jaffna (0.15 mg/mL). The results of HPLC quantification of anticancer compounds [beta-sitosterol (0.244%), quercetin (0.216%), kaempferol (0.013%), and moringin (0.063%)] was also in consonance with that of MTT assay. In summary, the trend observed in all the parameters tested was Jaffna > PKM-1 > PKM-2 > ODC > conventional. Thus, Jaffna variety has a better potential to combat malnutrition and cancer and must be recommended for commercial plantations.

scholarly journals Effect of Moringa oleifera Lam. Leaf Tea on Sexual Behavior and Reproductive Function in Male Rats

Plants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2019
Author(s):  
Jiraporn Laoung-on ◽  
Kanokporn Saenphet ◽  
Churdsak Jaikang ◽  
Paiwan Sudwan
Keyword(s):  
Sexual Behavior ◽  
Reproductive System ◽  
Moringa Oleifera ◽  
Antioxidant Activities ◽  
Courtship Behavior ◽  
Reproductive Function ◽  
Male Reproductive System ◽  
Male Rats ◽  
Total Phenols ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (M. oleifera) has been called the “miracle tree” due to its attributes for therapy in various diseases. However, M. oleifera studies on the male reproductive system have been limited. The aim of this study was a phytochemical screening and investigation of the effects of M. oleifera leaf tea on sexual behavior, reproductive function and antioxidant activities. Male rats were fed with M. oleifera leaf tea extract at doses of 0.55, 1.10 and 2.20 mg/kg or distilled water for 30 days. The result showed that M. oleifera leaf tea contained rich total phenols and flavonoids. The courtship behavior, seminiferous tubule diameter, epithelium height, epithelium area, type A spermatogonia, and spermatogonia efficiency were significantly increased in all treatment groups. The groups treated with 1.10 and 2.20 mg/kg increased the number of Sertoli cells. The total of spermatogenic cells increased in the group treated with 0.55 mg/kg. M. oleifera leaf tea scavenged DPPH radical, ABTS radical and H2O2, and inhibited LPO and AGEs formation. Due to M. oleifera leaf tea containing rich total phenols, flavonoids, and antioxidants, it could enhance sexual function and the male reproductive system.

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