scholarly journals Performance of Intergrowth 21st Growth Charts in the Diagnosis of Small and Large for Gestational Age in Term and Preterm Newborns

2020 ◽  
Vol 33 (1) ◽  
pp. 15
Author(s):  
Bárbara Marques ◽  
Rosa Martins ◽  
Teresa Rodrigues ◽  
Graça Oliveira ◽  
Margarida Abrantes
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Neonatal Morbidity ◽  
Large For Gestational Age ◽  
Growth Charts ◽  
Very Preterm ◽  
Maternity Hospitals ◽  
Term Newborns ◽  
Preterm Newborns

Introduction: Birth weight is a major contributor to neonatal morbidity and mortality and is associated with chronic diseases in adulthood. This study aimed to evaluate the use of Intergrowth 21st instead of the Fenton & Kim 2013 growth charts in the diagnosis of small and large for gestational age in a group of Portuguese newborns.Material and Methods: We conducted an analytical and retrospective study to evaluate birth weight of term and preterm newborns using both growth charts. Groups studied: ‘Term-weeks’ and ‘Term-days’ (term newborns with gestational age in weeks and days, respectively), ‘Preterm-weeks’ and ‘Preterm-days’ (preterm newborns with gestational age in weeks and days, respectively).Results: A total of 14 056 newborns were included, 6% preterm. Using the Intergrowth 21st growth charts, the groups ‘Term-weeks’ (n = 12 081), ‘Term-days’ (n = 1118), ‘Preterm-weeks’ (n = 617) and ‘Preterm-days’ (n = 240), classified as small for gestational age according to the Fenton & Kim 2013 growth charts were adequate for gestational age in 52.8%, 57.8%, 37.7% and 9.3% respectively; and 9.2%, 9.2%, 5.9% and 0.6% of adequate for gestational age newborns were large for gestational age, respectively. In the ‘Pretermdays’ group, 7.9% of adequate for gestational age newborns were small for gestational age and 22.2% of large for gestational age newborns were adequate for gestational age, all with gestational age below 231 days.Discussion: The use of the Intergrowth 21st growth charts in this sample resulted in a lower number of newborns being classified as small for gestational age, except in very preterm newborns.Conclusion: Considering the results obtained, we suggest that Portuguese maternity hospitals use the Intergrowth 21st instead of the Fenton & Kim 2013 growth charts. However, more studies are needed to confirm these results.

New Reference for Neonatal Growth: 10-Year Data of Phramongkutklao Hospital

2020 ◽  
Vol 103 (12) ◽  
pp. 1284-1291
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Admission Rate ◽  
Large For Gestational Age ◽  
Growth Chart ◽  
Growth Charts ◽  
International Growth ◽  
Neonatal Growth ◽  
Growth Assessment

Background: Growth assessment including birth weight, length, and head circumference is important to identify infants at risk. However, using international growth curves may be inappropriate for growth assessment of Thai neonates. Objective: To generate a growth chart of infants at the Phramongkutklao Hospital (PMK), and to compare PMK’s growth chart assessment with other international growth charts. Materials and Methods: The authors generated a PMK growth chart from PMK’s newborn database between 2007 and 2016. Birth weight of infants born in 2017 was assessed by using the PMK growth chart in comparison with the Fenton, Lubchenco and Intergrowth Twenty-first growth charts. Results: To generate a PMK growth chart, 22,926 infants were enrolled to the present study. Comparing with other international growth charts, the Fenton exhibited a higher ninetieth percentile of birth weight than others, especially at gestational age of 36 to 41 weeks. In contrast, the Lubchenco exhibited the lowest tenth percentile of birth weight. In 2017, 2,314 infants were born and evaluated by using the PMK, the Fenton, the Lubchenco, and the Intergrowth-21st growth charts. Large for gestational age (LGA) was identified in 185 (8.64%), 55 (2.57%), 166 (7.75%) and 166 (7.75%) infants, respectively. In contrast, small for gestational age (SGA) was identified in 220 (10.27%), 228 (10.64%), 34 (1.59%) and 148 (6.91%) infants, respectively. The admission rate of infants diagnosed as LGA by PMK, but appropriate for gestational age (AGA) by Fenton was higher than other AGA infants. Conclusion: The PMK reference of neonatal growth is up-to-date and applicable. Growth assessment using the Fenton growth chart at late preterm and term gestations may be inaccurate to identify LGA infants. In contrast, the Lubchenco growth chart has limitation to identify SGA infants. Data accumulation from multi-centers at different regions of Thailand are warranted to generate a Thai neonatal growth reference. Keywords: Growth curve, Neonatal growth, Large for gestational age, Small for gestational age

Colloid Osmotic Pressure in Newborn Infants: Variations with Birth Weight, Gestational Age, Total Serum Solids, and Mean Arterial Pressure

PEDIATRICS ◽  
1981 ◽  
Vol 68 (6) ◽  
pp. 814-819
Author(s):  
Paul Y. K. Wu ◽  
Gary Rockwell ◽  
Linda Chan ◽  
Shu-Mei Wang ◽  
Vikram Udani
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Osmotic Pressure ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Newborn Infants ◽  
Colloid Osmotic Pressure ◽  
Large For Gestational Age ◽  
Total Serum ◽  
Arterial Blood

Colloid osmotic pressure (COP) of blood was measured directly at birth with the Wescor membrane colloid osmometer (model 4100) in 91 appropriately grown, 11 large, and nine small for gestational age "well" newborn infants. COP correlated directly with birth weight (r = .726, P < .00001) and gestational age (r = .753, P < .00001). COP values for small for gestational age (SGA) and large for gestational age (LGA) infants were found to fall within the 95% prediction interval with regard to birth weight and gestational age for appropriate for gestational age (AGA) infants. Simultaneous measurements of COP, total serum solids, and central arterial mean blood pressure were made. The results showed that COP correlated directly with total serum solids (r = .89, P < .0001) and mean arterial blood pressure (r = .660, P < .001). Among the factors evaluated, total serum solids was the best predictor of COP.

scholarly journals Gestational Weight Gain and Pregnancy Outcomes among Nulliparous Women

2019 ◽  
Author(s):  
Annie M. Dude ◽  
William Grobman ◽  
David Haas ◽  
Brian M. Mercer ◽  
Samuel Parry ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Gestational Weight Gain ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Pregnancy Outcomes ◽  
Large For Gestational Age ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Hypertensive Disorders

Abstract Objective To determine the association between total gestational weight gain and perinatal outcomes. Study Design Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 2009 Institute of Medicine guidelines. Outcomes examined included hypertensive disorders of pregnancy, mode of delivery, shoulder dystocia, large for gestational age or small for-gestational age birth weight, and neonatal intensive care unit admission. Results Among 8,628 women, 1,666 (19.3%) had inadequate, 2,945 (34.1%) had adequate, and 4,017 (46.6%) had excessive gestational weight gain. Excessive gestational weight gain was associated with higher odds of hypertensive disorders (adjusted odds ratio [aOR] = 2.05, 95% confidence interval [CI]: 1.78–2.36) Cesarean delivery (aOR = 1.24, 95% CI: 1.09–1.41), and large for gestational age birth weight (aOR = 1.49, 95% CI: 1.23–1.80), but lower odds of small for gestational age birth weight (aOR = 0.59, 95% CI: 0.50–0.71). Conversely, inadequate gestational weight gain was associated with lower odds of hypertensive disorders (aOR = 0.75, 95% CI: 0.62–0.92), Cesarean delivery (aOR = 0.77, 95% CI: 0.65–0.92), and a large for gestational age birth weight (aOR = 0.72, 95% CI: 0.55–0.94), but higher odds of having a small for gestational age birth weight (aOR = 1.64, 95% CI: 1.37–1.96). Conclusion Both excessive and inadequate gestational weight gain are associated with adverse maternal and neonatal outcomes.

scholarly journals PREDICTION OF FETAL BIRTH WEIGHT BY JOHNSON'S FORMULA & ULTRASONOGRAPHY COMPARED WITH ACTUAL BIRTH WEIGHT

2020 ◽  
pp. 1-2
Author(s):  
K. Thamara Veni ◽  
Gadam Swathi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Neonatal Morbidity ◽  
Birth Trauma ◽  
Fetal Weight ◽  
Large For Gestational Age ◽  
Accurate Estimation ◽  
Future Health ◽  
Fetal Birth Weight ◽  
Neonatal Problems

INTRODUCTION Birth weight is the greatest single factor which determines the survival of the fetus and future health of neonate. It is an important factor for prediction of neonatal problems. Accurate estimation of fetal weight is of paramount importance in the management of labor and delivery. Fetal weight is also important in assessing whether the fetus is small for gestational age or large for gestational age in order to have a good obstetrical decision making and also to avoid the intra partum distress, birth trauma and thereby to reduce the neonatal morbidity and mortality1.

scholarly journals Adverse effects of small for gestational age differ by gestational week among very preterm infants

2018 ◽  
Vol 104 (2) ◽  
pp. F192-F198 ◽  
Author(s):  
Erik A Jensen ◽  
Elizabeth E Foglia ◽  
Kevin C Dysart ◽  
Rebecca A Simmons ◽  
Zubair H Aghai ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Intraventricular Haemorrhage ◽  
Neonatal Morbidity ◽  
Excess Risk ◽  
Very Preterm Infants ◽  
Adjusted Risk ◽  
Very Preterm ◽  
Grade 3

ObjectiveTo characterise the excess risk for death, grade 3–4 intraventricular haemorrhage (IVH), bronchopulmonary dysplasia (BPD) and stage 3–5 retinopathy of prematurity independently associated with birth small for gestational age (SGA) among very preterm infants, stratified by completed weeks of gestation.MethodsRetrospective cohort study using the Optum Neonatal Database. Study infants were born <32 weeks gestation without severe congenital anomalies. SGA was defined as a birth weight <10th percentile. The excess outcome risk independently associated with SGA birth among SGA babies was assessed using adjusted risk differences (aRDs).ResultsOf 6708 infants sampled from 717 US hospitals, 743 (11.1%) were SGA. SGA compared with non-SGA infants experienced higher unadjusted rates of each study outcome except grade 3–4 IVH among survivors. The excess risk independently associated with SGA birth varied by outcome and gestational age. The highest aRD for death (0.27; 95% CI 0.13 to 0.40) occurred among infants born at 24 weeks gestation and declined as gestational age increased. In contrast, the peak aRDs for BPD among survivors (0.32; 95% CI 0.20 to 0.44) and the composites of death or BPD (0.35; 95% CI 0.24 to 0.46) and death or major morbidity (0.35; 95% CI 0.24 to 0.45) occurred at 27 weeks gestation. The risk-adjusted probability of dying or developing one or more of the evaluated morbidities among SGA infants was similar to that of non-SGA infants born approximately 2–3 weeks less mature.ConclusionThe excess risk for neonatal morbidity and mortality associated with being born SGA varies by adverse outcome and gestational age.

scholarly journals Association of Low Maternal Plasma Glucose after Oral Glucose Challenge Test with Small for Gestational Age Neonate

2012 ◽  
Vol 3 (1) ◽  
pp. 22-25 ◽  
Author(s):  
Pratap Kumar ◽  
Rajeshwari G Bhat ◽  
KV Bhagya
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Plasma Glucose ◽  
Small For Gestational Age ◽  
Challenge Test ◽  
Neonatal Morbidity ◽  
Maternal Plasma ◽  
Oral Glucose ◽  
Glucose Challenge Test ◽  
Glucose Challenge

ABSTRACT Aims and objectives To study the association of low maternal plasma sugar with birth weight and neonatal morbidity. Materials and methods Glucose challenge test was performed in low risk women, the birth weight and neonatal morbidities were compared between women with low GCT (<88 mg/dl) and normal GCT (88-139 mg/dl). Results Incidence of small for gestational age (<2500 gm) was significantly more in women with low GCT (17.3% vs 7.3%), but difference in NICU admission between the two groups was not significant statistically. Conclusion Prevalence of small for gestational age neonate was significantly higher in women with low GCT compared to women with normal GCT. How to cite this article Bhat RG, Bhagya KV, Kumar P. Association of Low Maternal Plasma Glucose after Oral Glucose Challenge Test with Small for Gestational Age Neonate. Int J Infertility Fetal Med 2012;3(1):22-25.

scholarly journals Perbedaan Berat Lahir Bayi Pasien Preeklampsia Berat / Eklampsia Early dan Late Onset di RSUP Dr. M. Djamil Padang

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Rizka Amelia ◽  
Ariadi Ariadi ◽  
Syaiful Azmi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Early Onset ◽  
Late Onset ◽  
Severe Preeclampsia ◽  
Large For Gestational Age ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

AbstrakPreeklampsia dan eklampsia tidak hanya berdampak bagi ibu, tetapi juga terhadap janin yang dikandungnya, seperti hambatan pertumbuhan janin intrauterin yang dapat dilihat dari berat lahir bayi tersebut. Ibu dengan preeklampsia berat/ eklampsia early onset cenderung melahirkan bayi dengan berat lahir Kecil untuk Masa Kehamilan (KMK), sementara yang  late onset cenderung melahirkan bayi dengan berat lahir Sesuai untuk Masa Kehamilan (SMK) atau bahkan Besar untuk Masa Kehamilan (BMK). Tujuannya penelitian ini adalah menentukan perbedaan berat lahir bayi pasien preeklampsia berat/ eklampsia early dan late onset. Penelitian ini dilaksanakan dari Oktober 2012 sampai Juli 2013 di bagian Rekam Medik RSUP Dr. M. Djamil Padang. Jenis penelitian yang digunakan adalah observasional analitik dengan desain cross sectional. Hasil penelitian menunjukkan bahwa angka kejadian preeklampsia berat/ eklampsia early onset adalah 26,1% dan yang late onset sebanyak 73,9%. Bayi KMK lebih banyak dilahirkan oleh ibu preeklampsia berat/ eklampsia early onset (16,67%) dibandingkan dengan yang  late onset (7,35%). Setelah dilakukan analisis melalui uji chi-square, disimpulkan bahwa tidak ada perbedaan berat lahir bayi antara pasien preeklampsia berat/eklampsia early dan late onset secara signifikan (p>0,05).Kata kunci: preeklampsia berat/eklampsia early onset, preeklampsia berat/eklampsia late onset, berat lahir bayi AbstractPreeclampsia and eclampsia are not only effect to mother, but also influent to the fetus, such as intrauterine fetal growth retardation  which can be seen as baby's birth weight. Mothers with early onset severe preeclampsia / eclampsia tend to give birth small for gestational age  babies, while the late onset tend to give birth normal birth weight or large for gestational age babies. The objective of this study was to determine the differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia. The research was conducted from October 2012 to July 2013 at the medical records department of general hospital center Dr. M. Djamil Padang. The type of this research was observational analytic with cross sectional design. The results showed that the incidence of early onset severe preeclampsia/ eclampsia was 26.1% and late onset was 73.9%. Small for gestational age babies born from mothers with early onset severe preeclampsia/ eclampsia (16.67%) is more than the late onset (7.35%). After analyzed by chi square test, it was concluded that there was no differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia significantly (p> 0,05).Keywords: early onset severe preeclampsia/eclampsia, late onset severe preeclampsia/eclampsia, baby’s birth weight

Fetal Macrosomia

2019 ◽  
Author(s):  
Caitlin Clifford ◽  
Andrea G. Edlow
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Neonatal Morbidity ◽  
Developed Countries ◽  
Shoulder Dystocia ◽  
Fetal Weight ◽  
Fetal Macrosomia ◽  
Large For Gestational Age ◽  
Obesity Epidemic ◽  
Adverse Pregnancy

Excessive fetal growth and increased birth weight are associated with significant maternal and neonatal morbidity and have become increasingly common given the global obesity epidemic.  Fetal macrosomia is traditionally defined in developed countries as fetal weight greater than 4,000 grams or 4,500 grams regardless of gestational age.  Large-for-gestational-age is traditionally defined as birth weight equal to or greater than the ninetieth percentile for a given gestational age.  Both are associated with a continuum of risk for complications, including shoulder dystocia, birth trauma, stillbirth, and infant mortality.  Diabetes is strongly associated with macrosomia, and control of maternal hyperglycemia has been proven to decrease rates of macrosomia and associated adverse pregnancy outcomes. Pregnancy-based interventions to minimize gestational weight gain have failed to consistently demonstrate a significant impact on macrosomia. This review contains 5 tables, and 77 references. Keywords: pregnancy, macrosomia, large for gestational age, estimated fetal weight, diabetes, obesity, shoulder dystocia, cesarean delivery, stillbirth

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