Total Antioxidant Capacity and Antioxidant Enzymes in Serum, Saliva, and Gingival Crevicular Fluid of Preeclamptic Women With and Without Periodontal Disease

2007 ◽  
Vol 78 (8) ◽  
pp. 1602-1611 ◽  
Author(s):  
Varol Canakci ◽  
Abdulkadir Yildirim ◽  
Cenk Fatih Canakci ◽  
Abubekir Eltas ◽  
Yasin Cicek ◽  
...  
Keyword(s):  
Antioxidant Enzymes ◽  
Periodontal Disease ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Gingival Crevicular Fluid ◽  
Total Antioxidant ◽  
Crevicular Fluid

scholarly journals Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Martina Horvathova ◽  
Zuzana Orszaghova ◽  
Lucia Laubertova ◽  
Magdalena Vavakova ◽  
Peter Sabaka ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzymes ◽  
Antioxidant Capacity ◽  
Healthy Volunteers ◽  
Total Antioxidant Capacity ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Total Antioxidant ◽  
Trolox Equivalent ◽  
Markers Of Oxidative Stress

We examinedin vitroantioxidant capacity of polyphenolic extract obtained from the wood of oakQuercus robur(QR), Robuvit, using TEAC (Trolox equivalent antioxidant capacity) method and the effect of its intake on markers of oxidative stress, activity of antioxidant enzymes, and total antioxidant capacity in plasma of 20 healthy volunteers. Markers of oxidative damage to proteins, DNA, and lipids and activities of Cu/Zn-superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were determined in the erythrocytes. We have found anin vitroantioxidant capacity of Robuvit of 6.37 micromole Trolox equivalent/mg of Robuvit. One month intake of Robuvit in daily dose of 300 mg has significantly decreased the serum level of advanced oxidation protein products (AOPP) and lipid peroxides (LP). Significantly increased activities of SOD and CAT as well as total antioxidant capacity of plasma after one month intake of Robuvit have been shown. In conclusion, we have demonstrated for the first time that the intake of Robuvit is associated with decrease of markers of oxidative stress and increase of activity of antioxidant enzymes and total antioxidant capacity of plasmain vivo.

scholarly journals COMPARATIVE ESTIMATION OF SALIVARY TOTAL ANTIOXIDANT CAPACITY IN PERIODONTAL HEALTH AND CHRONIC PERIODONTITIS - A PILOT STUDY

2018 ◽  
Vol 11 (10) ◽  
pp. 523
Author(s):  
U Raghavendra ◽  
Anupama Rao ◽  
Jyothi D'suoza ◽  
Vinita Ramanath Pai ◽  
Sindhu Nair ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Antioxidant Capacity ◽  
Chronic Periodontitis ◽  
Total Antioxidant Capacity ◽  
Sample Collection ◽  
Periodontal Health ◽  
Total Antioxidant ◽  
Biochemical Estimation ◽  
Unpaired Student ◽  
Method Analysis

Objective: Gram-negative bacteria provoke polymorphonuclear leukocyte (PMN) to release reactive oxygen species in chronic periodontitis (CP). Inability to maintain a balance between oxidative stress and antioxidant levels makes patients more susceptible to periodontal disease. The present study aims to estimate and compare salivary total antioxidant capacity (TAOC) in subjects with clinically healthy periodontium and patients with CP.Methods: After fulfilling the selection criteria, a total of 20 subjects (10 with clinically healthy periodontium and 10 with CP) were subjected to unstimulated salivary sample collection for biochemical estimation of TAOC by spectrophotometric assay using Kovacevic method. Analysis of data was done with unpaired student t-test, using SPSS version 22 statistical program.Results: Salivary TAOC was significantly higher in subjects with clinically healthy periodontium compared to CP patients. It was statistically significant (p<0.001).Conclusion: This study indicated increased levels of salivary TAOC in patients with CP compared to clinically healthy periodontium. Alteration in defensive antioxidant status could be a risk factor in the progression of periodontal disease.

scholarly journals White Tea Intake Abrogates Markers of Streptozotocin-Induced Prediabetes Oxidative Stress in Rat Lungs’

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3894
Author(s):  
Ana C. Silveira ◽  
Luís Rato ◽  
Pedro Fontes Oliveira ◽  
Marco G. Alves ◽  
Branca M. Silva
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Enzymes ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Chemical Properties ◽  
Histone H2a ◽  
Protein Nitration ◽  
White Tea ◽  
Lung Dysfunction ◽  
Total Antioxidant

Prediabetes (PrDM) is a prodromal stage of diabetes mellitus (DM) with an increasing prevalence worldwide. During DM progression, individuals gradually develop complications in various organs. However, lungs are suggested to be affected later than other organs, such as the eyes, heart or brain. In this work, we studied the effects of PrDM on male Wistar rats’ lungs and whether the regular consumption of white tea (WTEA) for 2 months contributes to the improvement of the antioxidant profile of this tissue, namely through improved activity of the first line defense antioxidant enzymes, the total antioxidant capacity and the damages caused in proteins, lipids and histone H2A. Our data shows that PrDM induced a decrease in lung superoxide dismutase and glutathione peroxidase activities and histone H2A levels and an increase in protein nitration and lipid peroxidation. Remarkably, the regular WTEA intake improved lung antioxidant enzymes activity and total antioxidant capacity and re-established the values of protein nitration, lipid peroxidation and histone H2A. Overall, this is the first time that lung is reported as a major target for PrDM. Moreover, it is also the first report showing that WTEA possesses relevant chemical properties against PrDM-induced lung dysfunction.

scholarly journals Total Oxidant and Antioxidant Capacity of Gingival Crevicular Fluid and Saliva in Patients with Periodontitis: Review and Clinical Study

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 450 ◽  
Author(s):  
Joanna Toczewska ◽  
Mateusz Maciejczyk ◽  
Tomasz Konopka ◽  
Anna Zalewska
Keyword(s):  
Antioxidant Capacity ◽  
Gingival Crevicular Fluid ◽  
Synergistic Effects ◽  
Stress Index ◽  
Enzymatic Antioxidants ◽  
Total Antioxidant ◽  
Clinical Indices ◽  
Total Antioxidative Capacity ◽  
Severity Of The Disease ◽  
Crevicular Fluid

Periodontitis is inextricably linked to oxidative-reductive (redox) imbalance. However, little is still known about the resultant ability to scavenge oxygen free radicals in saliva and gingival crevicular fluid in patients with periodontitis. The multitude of enzymatic and non-enzymatic antioxidants and their synergistic effects cause an interest in the evaluation of the total antioxidative capacity. Thus, our study aimed to evaluate the total oxidative and antioxidative activity of gingival crevicular fluid and saliva in the periodontitis, as well as to relate these biomarkers to clinical indices of periodontopathy. Additionally, by calculating the oxidative stress index (OSI), the intensity of redox disturbances was also evaluated. Fifty-eight periodontitis patients were included in the study and divided into two subgroups depending on the severity of the disease. In the non-stimulated/stimulated saliva as well as a gingival crevicular fluid of the study group, we found significantly higher OSI and total oxidant status (TOS) as well as lower total antioxidant capacity (TAC). However, the ability to reduce iron ions (FRAP) was significantly lower only in stimulated and non-stimulated saliva of patients with periodontitis. The examined parameters correlated with the periodontium’s clinical condition, which indicates the exacerbation of the inflammatory process. However, TAC, TOS, OSI, and FRAP did not differentiate individual stages of periodontitis.

scholarly journals Comparison of the effects of three different Baccaurea angulata whole fruit juice doses on plasma, aorta and liver MDA levels, antioxidant enzymes and total antioxidant capacity

2017 ◽  
Vol 57 (5) ◽  
pp. 1817-1828 ◽  
Author(s):  
Muhammad Ibrahim ◽  
Maryam Abimbola Mikail ◽  
Idris Adewale Ahmed ◽  
Norazlanshah Hazali ◽  
Mohammad Syaiful Bahari Abdul Rasad ◽  
...  
Keyword(s):  
Antioxidant Enzymes ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Fruit Juice ◽  
Total Antioxidant
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