scholarly journals Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

Oncotarget ◽  
2016 ◽  
Vol 7 (18) ◽  
pp. 25604-25619 ◽  
Author(s):  
Fengxin Zhu ◽  
Wei Liu ◽  
Tang Li ◽  
Jiao Wan ◽  
Jianwei Tian ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Renal Fibrosis ◽  
Tubular Epithelial Cell ◽  
Cycle Arrest

scholarly journals MicroRNA‐493 targets STMN‐1 and promotes hypoxia‐induced epithelial cell cycle arrest in G 2 /M and renal fibrosis

2018 ◽  
Vol 33 (2) ◽  
pp. 1565-1577 ◽  
Author(s):  
Ting Liu ◽  
Limin Liu ◽  
Minna Liu ◽  
Rui Du ◽  
Yangjie Dang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Renal Fibrosis ◽  
Cycle Arrest

scholarly journals FP310MICRORNA493 TARGETS STMN1 AND PROMOTES HYPOXIA INDUCED EPITHELIAL CELL CYCLE ARREST IN G2/MAND RENAL FIBROSIS

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i135-i136
Author(s):  
Shiren Sun ◽  
Ting Liu ◽  
Limin Liu ◽  
Minna Liu ◽  
Rui Du ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Renal Fibrosis ◽  
Cycle Arrest

scholarly journals Sonic Hedgehog Opposes Epithelial Cell Cycle Arrest

1999 ◽  
Vol 147 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Hongran Fan ◽  
Paul A. Khavari
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Sonic Hedgehog ◽  
Growth Arrest ◽  
Epidermal Hyperplasia ◽  
Shh Pathway ◽  
Cycle Arrest ◽  
Pathway Activation

Stratified epithelium displays an equilibrium between proliferation and cell cycle arrest, a balance that is disrupted in basal cell carcinoma (BCC). Sonic hedgehog (Shh) pathway activation appears sufficient to induce BCC, however, the way it does so is unknown. Shh-induced epidermal hyperplasia is accompanied by continued cell proliferation in normally growth arrested suprabasal cells in vivo. Shh-expressing cells fail to exit S and G2/M phases in response to calcium-induced differentiation and also resist exhaustion of replicative growth capacity. In addition, Shh blocks p21CIP1/WAF1-induced growth arrest. These data indicate that Shh promotes neoplasia by opposing normal stimuli for epithelial cell cycle arrest.

scholarly journals Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

2010 ◽  
Vol 16 (5) ◽  
pp. 535-543 ◽  
Author(s):  
Li Yang ◽  
Tatiana Y Besschetnova ◽  
Craig R Brooks ◽  
Jagesh V Shah ◽  
Joseph V Bonventre
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Kidney Fibrosis ◽  
Cycle Arrest

Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest*

2003 ◽  
Vol 31 (6) ◽  
pp. 1630-1637 ◽  
Author(s):  
Craig M. Coopersmith ◽  
Paul E. Stromberg ◽  
Christopher G. Davis ◽  
W. Michael Dunne ◽  
Daniel M. Amiot ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Pseudomonas Aeruginosa ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Cycle Arrest ◽  
Intestinal Proliferation

scholarly journals Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion

EMBO Reports ◽  
2021 ◽  
Author(s):  
Shun Akaeda ◽  
Yasushi Hirota ◽  
Yamato Fukui ◽  
Shizu Aikawa ◽  
Ryoko Shimizu‐Hirota ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Arrest ◽  
Retinoblastoma Protein ◽  
Uterine Epithelial Cell ◽  
Cycle Arrest
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