scholarly journals Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma

Oncotarget ◽  
2015 ◽  
Vol 6 (37) ◽  
pp. 40223-40234 ◽  
Author(s):  
Ju-Bo Zhang ◽  
Bo Zhang ◽  
Lei-Guo ◽  
Zhen-Hai Lin ◽  
Xiao-Qiang Li ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Curative Resection ◽  
Independent Prognostic Marker

scholarly journals Corrigendum to “Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma”

2017 ◽  
Vol 2017 ◽  
pp. 1-1
Author(s):  
Xiao-Meng Dai ◽  
Tao Huang ◽  
Sheng-Li Yang ◽  
Xiu-Mei Zheng ◽  
George G. Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Curative Resection ◽  
Independent Prognostic Marker

AIB1 as an Independent Prognostic Marker in Hepatocellular Carcinoma After Hepatic Resection

2011 ◽  
Vol 16 (2) ◽  
pp. 356-360 ◽  
Author(s):  
Jun-Min Song ◽  
Min Lu ◽  
Fang-Fang Liu ◽  
Xiao-Juan Du ◽  
Bao-Cai Xing
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatic Resection ◽  
Prognostic Marker ◽  
Independent Prognostic Marker

scholarly journals The expression status of ZIC2 is an independent prognostic marker of hepatocellular carcinoma

2020 ◽  
Vol 4 (1) ◽  
pp. 40-46
Author(s):  
Qinglei Kong ◽  
Wenchao Li ◽  
Pan Hu ◽  
Hua Zeng ◽  
Yuhang Pan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Independent Prognostic Marker ◽  
Expression Status

scholarly journals Increased Expression of Cathepsin L: A Novel Independent Prognostic Marker of Worse Outcome in Hepatocellular Carcinoma Patients

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e112136 ◽  
Author(s):  
Jian Ruan ◽  
Hang Zheng ◽  
Wenguang Fu ◽  
Peng Zhao ◽  
Ning Su ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Cathepsin L ◽  
Independent Prognostic Marker

scholarly journals Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Xiao-Meng Dai ◽  
Tao Huang ◽  
Sheng-Li Yang ◽  
Xiu-Mei Zheng ◽  
George G. Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Tumor Biology ◽  
Proportional Hazard ◽  
Independent Prognostic Marker ◽  
Cox Proportional Hazard ◽  
Good Target ◽  
B Virus ◽  
Cox Proportional Hazard Regression ◽  
Curative Hepatectomy

Accumulating evidence suggests that the tumor microenvironment has a profound influence on tumor initiation and progression, opening a new avenue for studying tumor biology. Nonetheless, the prognostic values of the peritumoral expression of EpCAM and CD13 remain to be elucidated in hepatocellular carcinoma (HCC) patients. In this study, the expression of EpCAM and CD13 was assessed by immunohistochemistry in peritumoral liver hepatocytes from 106 hepatitis B virus- (HBV-) related HCC patients who had undergone curative hepatectomy. The peritumoral EpCAM-positive group had a significantly worse overall survival (OS) (p=0.003) and recurrence-free survival (RFS) (p=0.022) compared to the negative group. Peritumoral CD13-positive patients were also associated with poor OS (p=0.038), while not significantly associated with RFS. The adjusted multivariate COX proportional hazard regression analysis suggested that only the positive expression of peritumoral EpCAM precisely predicted poor OS. Being peritumoral EpCAM positive was also significantly associated with a larger tumor size, liver cirrhosis, and more frequent vascular invasion; however, no statistically significant association was observed between CD13 and any clinicopathological features. Taken together, peritumoral EpCAM and CD13 expression was associated with a poor prognosis, but EpCAM may be a better prognostic marker than CD13 in HBV-related HCC patients. In the future, peritumoral EpCAM could be a good target for adjuvant therapy after curative hepatectomy.

scholarly journals Glyoxylate Reductase/Hydroxypyruvate Reductase: A Novel Prognostic Marker for Hepatocellular Carcinoma Patients after Curative Resection

Pathobiology ◽  
2013 ◽  
Vol 80 (3) ◽  
pp. 155-162 ◽  
Author(s):  
Yinglian Pan ◽  
Runzhou Ni ◽  
Qingchun Deng ◽  
Xiaodong Huang ◽  
Yixin Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Curative Resection ◽  
Hydroxypyruvate Reductase ◽  
Glyoxylate Reductase

scholarly journals ATAD2 as a Poor Prognostic Marker for Hepatocellular Carcinoma after Curative Resection

2015 ◽  
Vol 47 (4) ◽  
pp. 853-861 ◽  
Author(s):  
Hye Won Hwang ◽  
Sang Yun Ha ◽  
Heejin Bang ◽  
Cheol-Keun Park
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Curative Resection
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