scholarly journals Preoperative Neutrophil-to-Lymphocyte Ratio as a New Prognostic Marker in Hepatocellular Carcinoma after Curative Resection

2014 ◽  
Vol 7 (2) ◽  
pp. 248-255 ◽  
Author(s):  
Weijia Liao ◽  
Jingmei Zhang ◽  
Qun Zhu ◽  
Liling Qin ◽  
Wenmin Yao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Marker ◽  
Curative Resection ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Preoperative Neutrophil-to-Lymphocyte Ratio Plus Platelet-to-Lymphocyte Ratio Predicts the Outcomes after Curative Resection for Hepatocellular Carcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
T. Kabir ◽  
M. Ye ◽  
N. A. Mohd Noor ◽  
W. Woon ◽  
S. P. Junnarkar ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Resection ◽  
Curative Resection ◽  
Scoring Systems ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet To Lymphocyte Ratio ◽  
Roc Curve Analysis ◽  
Curative Intent ◽  
Lymphocyte Ratio

Background. In recent years, inflammation-based scoring systems have been reported to predict survival in Hepatocellular Carcinoma (HCC). The aim of our study was to validate combined preoperative Neutrophil-to-Lymphocyte ratio (NLR)-Platelet-to-Lymphocyte ratio (PLR) in predicting overall survival (OS) and recurrence free survival (RFS) in patients who underwent curative resection for HCC. Methods. We conducted a retrospective study of HCC patients underwent liver resection with curative intent from January 2010 to December 2013. Receiver-operating characteristic (ROC) curve analysis was used to determine the optimal cut-off values for NLR and PLR. Patients with both NLR and PLR elevated were allocated a score of 2; patients showing one or neither of these indices elevated were accorded a score of 1 or 0, respectively. Results. 132 patients with a median age of 66 years (range 18-87) underwent curative resection for HCC. Overall morbidity was 30.3%, 30-day mortality was 2.3%, and 90-day mortality was 6.8%. At a median follow-up of 24 months (range 1-88), 25% patients died, and 40.9% had recurrence. On multivariate analysis, elevated preoperative NLR-PLR was predictive of both OS (HR 2.496; CI 1.156-5.389; p=0.020) and RFS (HR 1.917; CI 1.161-3.166; p=0.011). The 5-year OS was 76% for NLR-PLR=0 group, 21.7% for the NLR-PLR=1 group, and 61.1% for the NLR-PLR=2 group, respectively. The 5-year RFS was 39.3% for the NLR-PLR=0 group, 18.4% for the NLR-PLR=1 group, and 21.1% for the NLR-PLR=2 group, respectively. Conclusion. The preoperative NLR-PLR is predictive of both OS and RFS in patients with HCC undergoing curative liver resection.

Impact of neutrophil to lymphocyte ratio on survival for hepatocellular carcinoma after curative resection

2017 ◽  
Vol 24 (10) ◽  
pp. 559-569 ◽  
Author(s):  
Hao-Chien Hung ◽  
Jin-Chiao Lee ◽  
Chih-Hsien Cheng ◽  
Tsung-Han Wu ◽  
Yu-Chao Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Curative Resection ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Neutrophil -To- Lymphocyte Ratio [NLR] as A Promising Prognostic Marker in Critically Ill Septic Patients

2022 ◽  
Vol 86 (1) ◽  
pp. 242-249
Author(s):  
Khaled Ali Esmaeil Ali Shalaby ◽  
Afaf Abdel Hafez Abdel Mageed ◽  
Tarek Elsayed Gouda
Keyword(s):  
Critically Ill ◽  
Prognostic Marker ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio
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