scholarly journals Dietary fat and fatty acid intake and epithelial ovarian cancer risk: evidence from epidemiological studies

Oncotarget ◽  
2015 ◽  
Vol 6 (40) ◽  
pp. 43099-43119 ◽  
Author(s):  
Rui Hou ◽  
Qi-Jun Wu ◽  
Ting-Ting Gong ◽  
Luo Jiang
Keyword(s):  
Ovarian Cancer ◽  
Fatty Acid ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Dietary Fat ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk ◽  
Fatty Acid Intake ◽  
Acid Intake

scholarly journals Dietary fat intake and ovarian cancer risk: a meta-analysis of epidemiological studies

Oncotarget ◽  
2016 ◽  
Vol 7 (24) ◽  
pp. 37390-37406 ◽  
Author(s):  
Wenlong Qiu ◽  
Heng Lu ◽  
Yana Qi ◽  
Xiuwen Wang
Keyword(s):  
Ovarian Cancer ◽  
Cancer Risk ◽  
Dietary Fat ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk ◽  
Fat Intake ◽  
Dietary Fat Intake

scholarly journals Circulating Insulin-Like Growth Factor-1 Level and Ovarian Cancer Risk

2016 ◽  
Vol 38 (2) ◽  
pp. 589-597 ◽  
Author(s):  
Yiyang Li ◽  
Yang Li ◽  
Jialing Zhang ◽  
Changjun Zheng ◽  
He Zhu ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Growth Factor ◽  
Cancer Risk ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk ◽  
Insulin Like Growth Factor ◽  
Summary Odds Ratio

Background/Aims: Insulin-like growth factor-1 (IGF-1) has an important role in cells' proliferation, differentiation and apoptosis, and it may be involved in carcinogenesis. Several epidemiological studies assessed the association between circulating IGF-1 level and ovarian cancer risk, but there was still no conclusive finding. Methods: A meta-analysis of published studies was performed to assess the association between circulating IGF-1 level and ovarian cancer risk. The summary odds ratio (OR) with 95% confidence interval (95%CI) was calculated through meta-analysis to evaluate the strength of the association. Results: Five eligible studies were included into the meta-analysis, which involved a total of 2,028 cases of ovarian cancer and 4,625 controls. Meta-analysis of total 5 studies showed that high circulating IGF-1 level was correlated with decreased risk of ovarian cancer (OR = 0.84, 95%CI 0.74-0.97, P = 0.013). After adjusting for heterogeneity, high circulating IGF-1 level was still correlated with decreased risk of ovarian cancer (OR = 0.83, 95%CI 0.72-0.95, P = 0.007). Subgroup analysis by age showed that circulating IGF-1 level was not correlated with ovarian cancer risk in women both less than 55 years and more than 55 years. However, after adjusting for heterogeneity, high circulating IGF-1 level was correlated with decreased ovarian cancer risk in women less than 55 years (OR = 0.82, 95%CI 0.72-0.94, P = 0.004). Conclusion: Our meta-analysis suggests that high circulating IGF-1 level may be correlated with decreased ovarian cancer risk, especially in women less than 55 years. More studies are needed to further assess the association between circulating IGF-1 level and ovarian cancer risk in the future.

scholarly journals Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

PLoS Medicine ◽  
2019 ◽  
Vol 16 (8) ◽  
pp. e1002893 ◽  
Author(s):  
James Yarmolinsky ◽  
Caroline L. Relton ◽  
Artitaya Lophatananon ◽  
Kenneth Muir ◽  
Usha Menon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ovarian Cancer ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Mendelian Randomization ◽  
Ovarian Cancer Risk ◽  
Mendelian Randomization Analysis ◽  
Randomization Analysis

scholarly journals Consumption of Fish and ω-3 Fatty Acids and Cancer Risk: An Umbrella Review of Meta-Analyses of Observational Studies

2020 ◽  
Vol 11 (5) ◽  
pp. 1134-1149 ◽  
Author(s):  
Keum Hwa Lee ◽  
Hyo Jin Seong ◽  
Gaeun Kim ◽  
Gwang Hun Jeong ◽  
Jong Yeob Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Cancer Risk ◽  
Observational Studies ◽  
Fatty Acid Intake ◽  
Umbrella Review ◽  
Acid Intake ◽  
Weak Evidence ◽  
Meta Analyses

ABSTRACT Multiple studies have suggested that ω-3 fatty acid intake may have a protective effect on cancer risk; however, its true association with cancer risk remains controversial. We performed an umbrella review of meta-analyses to summarize and evaluate the evidence for the association between ω-3 fatty acid intake and cancer outcomes. We searched PubMed, Embase, and the Cochrane Database of Systematic Reviews from inception to December 1, 2018. We included meta-analyses of observational studies that examined associations between intake of fish or ω-3 fatty acid and cancer risk (gastrointestinal, liver, breast, gynecologic, prostate, brain, lung, and skin) and determined the level of evidence of associations. In addition, we appraised the quality of the evidence of significant meta-analyses by using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. We initially screened 598 articles, and 15 articles, including 57 meta-analyses, were eligible. Among 57 meta-analyses, 15 reported statistically significant results. We found that 12 meta-analyses showed weak evidence of an association between ω-3 fatty acid intake and risk of the following types of cancer: liver cancer (n = 4 of 6), breast cancer (n = 3 of 14), prostate cancer (n = 3 of 11), and brain tumor (n = 2 of 2). In the other 3 meta-analyses, studies of endometrial cancer and skin cancer, there were no assessable data for determining the evidence levels. No meta-analysis showed convincing, highly suggestive, or suggestive evidence of an association. In the sensitivity analysis of meta-analyses by study design, we found weak associations between ω-3 fatty acid intake and breast cancer risk in cohort studies, but no statistically significant association in case-control studies. However, the opposite results were found in case of brain tumor risk. Although ω-3 fatty acids have been studied in several meta-analyses with regard to a wide range of cancer outcomes, only weak associations were identified in some cancer types, with several limitations. Considering the nonsignificant or weak evidence level, clinicians and researchers should cautiously interpret reported associations between ω-3 fatty acid consumption and cancer risks.

Adult lifetime alcohol consumption and invasive epithelial ovarian cancer risk in a population-based case–control study

2016 ◽  
Vol 140 (2) ◽  
pp. 277-284 ◽  
Author(s):  
Linda S. Cook ◽  
Andy C.Y. Leung ◽  
Kenneth Swenerton ◽  
Richard P. Gallagher ◽  
Anthony Magliocco ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Ovarian Cancer Risk ◽  
Invasive Epithelial Ovarian Cancer ◽  
Control Study

scholarly journals Evidence of Differential Effects of Vitamin D Receptor Variants on Epithelial Ovarian Cancer Risk by Predicted Vitamin D Status

2014 ◽  
Vol 4 ◽  
Author(s):  
Jennifer Prescott ◽  
Kimberly A. Bertrand ◽  
Brett M. Reid ◽  
Jennifer Permuth-Wey ◽  
Immaculata De Vivo ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Vitamin D Receptor ◽  
Ovarian Cancer Risk ◽  
Vitamin D Status ◽  
Differential Effects

Abstract 2829: Recreational physical activity and epithelial ovarian cancer risk in the California Teachers Study

2010 ◽  
Author(s):  
Yani Lu ◽  
Jane Sullivan-Halley ◽  
Ellen T. Chang ◽  
Katherine D. Henderson ◽  
James Lacey ◽  
...  
Keyword(s):  
Physical Activity ◽  
Ovarian Cancer ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Ovarian Cancer Risk ◽  
Recreational Physical Activity

Shift Work Patterns, Chronotype, and Epithelial Ovarian Cancer Risk

2019 ◽  
Vol 28 (5) ◽  
pp. 987-995 ◽  
Author(s):  
Lisa Leung ◽  
Anne Grundy ◽  
Jack Siemiatycki ◽  
Jocelyne Arseneau ◽  
Lucy Gilbert ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Risk ◽  
Epithelial Ovarian Cancer ◽  
Shift Work ◽  
Ovarian Cancer Risk ◽  
Work Patterns
Sign in / Sign up

Export Citation Format

Share Document