scholarly journals Dietary fat intake and ovarian cancer risk: a meta-analysis of epidemiological studies

Oncotarget ◽  
2016 ◽  
Vol 7 (24) ◽  
pp. 37390-37406 ◽  
Author(s):  
Wenlong Qiu ◽  
Heng Lu ◽  
Yana Qi ◽  
Xiuwen Wang
Keyword(s):  
Ovarian Cancer ◽  
Cancer Risk ◽  
Dietary Fat ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk ◽  
Fat Intake ◽  
Dietary Fat Intake

scholarly journals Adult dietary fat intake and ovarian cancer risk

2020 ◽  
Vol 146 (10) ◽  
pp. 2756-2772 ◽  
Author(s):  
Megan S. Rice ◽  
Elizabeth M. Poole ◽  
Walter C. Willett ◽  
Shelley S. Tworoger
Keyword(s):  
Ovarian Cancer ◽  
Cancer Risk ◽  
Dietary Fat ◽  
Ovarian Cancer Risk ◽  
Fat Intake ◽  
Dietary Fat Intake

scholarly journals Circulating Insulin-Like Growth Factor-1 Level and Ovarian Cancer Risk

2016 ◽  
Vol 38 (2) ◽  
pp. 589-597 ◽  
Author(s):  
Yiyang Li ◽  
Yang Li ◽  
Jialing Zhang ◽  
Changjun Zheng ◽  
He Zhu ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Growth Factor ◽  
Cancer Risk ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk ◽  
Insulin Like Growth Factor ◽  
Summary Odds Ratio

Background/Aims: Insulin-like growth factor-1 (IGF-1) has an important role in cells' proliferation, differentiation and apoptosis, and it may be involved in carcinogenesis. Several epidemiological studies assessed the association between circulating IGF-1 level and ovarian cancer risk, but there was still no conclusive finding. Methods: A meta-analysis of published studies was performed to assess the association between circulating IGF-1 level and ovarian cancer risk. The summary odds ratio (OR) with 95% confidence interval (95%CI) was calculated through meta-analysis to evaluate the strength of the association. Results: Five eligible studies were included into the meta-analysis, which involved a total of 2,028 cases of ovarian cancer and 4,625 controls. Meta-analysis of total 5 studies showed that high circulating IGF-1 level was correlated with decreased risk of ovarian cancer (OR = 0.84, 95%CI 0.74-0.97, P = 0.013). After adjusting for heterogeneity, high circulating IGF-1 level was still correlated with decreased risk of ovarian cancer (OR = 0.83, 95%CI 0.72-0.95, P = 0.007). Subgroup analysis by age showed that circulating IGF-1 level was not correlated with ovarian cancer risk in women both less than 55 years and more than 55 years. However, after adjusting for heterogeneity, high circulating IGF-1 level was correlated with decreased ovarian cancer risk in women less than 55 years (OR = 0.82, 95%CI 0.72-0.94, P = 0.004). Conclusion: Our meta-analysis suggests that high circulating IGF-1 level may be correlated with decreased ovarian cancer risk, especially in women less than 55 years. More studies are needed to further assess the association between circulating IGF-1 level and ovarian cancer risk in the future.

scholarly journals Breastfeeding and Ovarian Cancer Risk: a Systematic Review and Meta-analysis of 40 Epidemiological Studies

2014 ◽  
Vol 15 (12) ◽  
pp. 4829-4837 ◽  
Author(s):  
Da-Peng Li ◽  
Chen Du ◽  
Zuo-Ming Zhang ◽  
Guang-Xiao Li ◽  
Zhi-Fu Yu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Cancer ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Ovarian Cancer Risk
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