scholarly journals Molecular analyses of prostate tumors for diagnosis of malignancy on fine-needle aspiration biopsies

Oncotarget ◽  
2017 ◽  
Vol 8 (62) ◽  
pp. 104761-104771 ◽  
Author(s):  
Menglin Shan ◽  
Qianlin Xia ◽  
Dong Yan ◽  
Yanjun Zhu ◽  
Xuan Zhang ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Prostate Tumors ◽  
Molecular Analyses ◽  
Fine Needle

scholarly journals Prostate Tumors Diagnosis: Place of Fine Needle Aspiration in Congolese Patients

2020 ◽  
Vol 10 (01) ◽  
pp. 1-15
Author(s):  
C. F. S. Ngatali ◽  
S. E. Okouango ◽  
A. F. Bolenga Liboko ◽  
L. M. A. Boumba ◽  
E. Ndounga ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Prostate Tumors ◽  
Fine Needle

scholarly journals Diagnosis of Hodgkin Lymphoma from Cell Block: A Reliable and Helpful Tool in “Selected” Diagnostic Practice

Diagnostics ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 748
Author(s):  
Paola Parente ◽  
Claudia Covelli ◽  
Magda Zanelli ◽  
Domenico Trombetta ◽  
Illuminato Carosi ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Cell Block ◽  
Ultrasound Guided ◽  
Block Method ◽  
Molecular Analyses ◽  
Fine Needle ◽  
Conventional Cytology ◽  
Morphological Evaluation

Background: The diagnosis of lymphoma requires surgical specimens to perform morphological evaluation, immunohistochemical and molecular analyses. Ultrasound-guided fine needle aspiration may represent an appropriate first approach to obtain cytological samples in impalpable lesions and/or in patients unsuitable for surgical procedures. Although cytology has intrinsic limitations, the cell block method may increase the possibility of achieving an accurate diagnosis. Methods: We retrospectively selected a total of 47 ultrasound-guided fine needle aspiration and drainage samples taken from patients with effusion and deep-seated lesions which are clinically suspicious in terms of malignancy. Results: In 27 cases, both cell block and conventional cytology were performed: 21/27 cell blocks were adequate for the diagnosis of lymphoma and suitable for immunocytochemistry and molecular analyses vs. 12/20 samples to which only conventional cytology was applied. Moreover, in five patients we were able to make a diagnosis of Hodgkin lymphoma with the cell block (CB) technique. Conclusions: Contrary to conventional cytology, the cell block method may allow immunocytochemistry and molecular studies providing useful information for the diagnosis and subtypization of lymphoma in patients unsuitable for surgical procedure or with deep-seated lesions or extra-nodal diseases; additionally, it is a daily, simple and helpful approach. Moreover, we describe the usefulness of cell blocks in the diagnosis of Hodgkin lymphoma.

Fine-needle aspiration for nucleic acid-ased molecular analyses in breast cancer

2009 ◽  
Vol 117 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Catherine Uzan ◽  
Fabrice Andre ◽  
Veronique Scott ◽  
Isabelle Laurent ◽  
Elie Azria ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Nucleic Acid ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Molecular Analyses ◽  
Fine Needle
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