scholarly journals Cordycepin and a preparation from Cordyceps militaris inhibit malignant transformation and proliferation by decreasing EGFR and IL-17RA signaling in a murine oral cancer model

Oncotarget ◽  
2017 ◽  
Vol 8 (55) ◽  
pp. 93712-93728 ◽  
Author(s):  
Peng-Yang Hsu ◽  
Yueh-Hsin Lin ◽  
Erh-Ling Yeh ◽  
Hui-Chen Lo ◽  
Tai-Hao Hsu ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Malignant Transformation ◽  
Cordyceps Militaris ◽  
Cancer Model

Hamster Oral Cancer Model

2003 ◽  
pp. 141-171
Author(s):  
Joel Schwartz ◽  
Xinbin Gu
Keyword(s):  
Oral Cancer ◽  
Cancer Model

Luminescent Lanthanide Chelate Contrast Agents and Detection of Lesions in the Hamster Oral Cancer Model

2003 ◽  
Vol 57 (10) ◽  
pp. 1216-1222 ◽  
Author(s):  
Darryl J. Bornhop ◽  
John M. M. Griffin ◽  
Timothy S. Goebel ◽  
Mark R. Sudduth ◽  
Brent Bell ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Contrast Agents ◽  
Cancer Model ◽  
Lanthanide Chelate

scholarly journals IL‐1β Promotes Malignant Transformation and Tumor Aggressiveness in Oral Cancer

2014 ◽  
Vol 230 (4) ◽  
pp. 875-884 ◽  
Author(s):  
Chia‐Huei Lee ◽  
Jeffrey Shu‐Ming Chang ◽  
Shih‐Han Syu ◽  
Thian‐Sze Wong ◽  
Jimmy Yu‐Wai Chan ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Malignant Transformation ◽  
Tumor Aggressiveness

scholarly journals An Update on Precancerous Lesions of Oral Cavity

2018 ◽  
Vol 2 (1) ◽  
pp. 70 ◽  
Author(s):  
Deepak Goyal ◽  
Pardeep Goyal ◽  
Harkanwal Preet Singh ◽  
Chanchal Verma
Keyword(s):  
Head And Neck Cancer ◽  
Survival Rate ◽  
High Risk ◽  
Oral Cancer ◽  
Malignant Transformation ◽  
Death Rate ◽  
Precancerous Lesions ◽  
Correct Diagnosis ◽  
Premalignant Lesions ◽  
Timely Treatment

Oral cancer is the most common head and neck cancer, found in 270,000 patients annually worldwide. Some cancers develop from precancerous lesions; however, there is no definitive clinico pathological factor or biomarker that reliably enables malignant transformation to be predicted in an individual patient. Early detection and early treatment of oral cancer are important for improving the survival rate of patients; prevention of oral cancer will clearly contribute most to decreasing its death rate. So correct diagnosis and timely treatment of premalignant lesions with high risk of malignant transformation may help to prevent malignant transformation.

Induction of invasion in an organotypic oral cancer model by CoCl2, a hypoxia mimetic

2010 ◽  
Vol 118 (2) ◽  
pp. 168-176 ◽  
Author(s):  
Ingvild J. Brusevold ◽  
Camilla Husvik ◽  
Olav Schreurs ◽  
Karl Schenck ◽  
Magne Bryne ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Model

Assessment and Comparison of Salivary Survivin Biomarker in Oral Leukoplakia, Oral Lichen Planus, and Oral Cancer: A Comparative Study

2017 ◽  
Vol 8 (2) ◽  
pp. 73-76 ◽  
Author(s):  
Ruchika Garg ◽  
Arvind V Shetti ◽  
Anjana S Bagewadi
Keyword(s):  
Oral Cancer ◽  
Comparative Study ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Control Group ◽  
Significant Difference ◽  
Potentially Malignant ◽  
Oral Lichen

ABSTRACT Introduction Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity. It is preceded by various potentially malignant conditions like oral leukoplakia and oral lichen planus. Survivin is an inhibitor of apoptosis whose levels have been found increased in oral cancer as well as various potentially malignant conditions. Thus survivin can act as a biomarker and help in early detection of potentially malignant conditions which can prevent its transformation into malignancy. Aim To assess and compare the level of total human salivary survivin in oral leukoplakia, oral lichen planus, oral cancer, and control group. Materials and methods A total of 96 subjects were included in the study, which were further grouped into 24 in each group. The saliva was analyzed for survivin level among all the four groups. Survivin concentration (pg/mL) was studied in relation to clinical data. The results were analyzed using Mann—Whitney U test to derive the statistical difference. Results The average of levels of survivin in control group was 0.199 pg/mL, in oral leukoplakia group 0.312 pg/mL, in oral lichen planus group 0.380 pg/mL, and in oral cancer group 0.430 pg/mL. A comparison of all these groups revealed statistically significant difference among the groups. Conclusion Survivin may not be considered as an independent predictor of the malignant transformation for premalignant lesions but it can be an indicator for an increased risk of malignant transformation. How to cite this article Garg R, Shetti AV, Bagewadi AS. Assessment and Comparison of Salivary Survivin Biomarker in Oral Leukoplakia, Oral Lichen Planus, and Oral Cancer: A Comparative Study. World J Dent 2017;8(2):73-76.

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