scholarly journals Multi-targeting therapeutic mechanisms of the Chinese herbal medicine QHD in the treatment of non-alcoholic fatty liver disease

Oncotarget ◽  
2017 ◽  
Vol 8 (17) ◽  
pp. 27820-27838 ◽  
Author(s):  
Qin Feng ◽  
Wensheng Liu ◽  
Susan S. Baker ◽  
Hongshan Li ◽  
Cheng Chen ◽  
...  
Keyword(s):  
Liver Disease ◽  
Herbal Medicine ◽  
Fatty Liver ◽  
Chinese Herbal Medicine ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Chinese Herbal ◽  
Therapeutic Mechanisms ◽  
Alcoholic Fatty Liver Disease

scholarly journals Acupuncture combined with Chinese herbal medicine on non-alcoholic fatty liver disease

Medicine ◽  
2021 ◽  
Vol 100 (51) ◽  
pp. e28083
Author(s):  
Yuan Ma ◽  
Kewei Sun ◽  
Jianzhong Cao ◽  
Xiaowu Qin ◽  
Jiaoling Shi ◽  
...  
Keyword(s):  
Liver Disease ◽  
Herbal Medicine ◽  
Fatty Liver ◽  
Chinese Herbal Medicine ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Chinese Herbal ◽  
Alcoholic Fatty Liver Disease

scholarly journals Protective effects of the herbal medicine goshajinkigan in a rat model of non-alcoholic fatty liver disease

2012 ◽  
Vol 33 (6) ◽  
pp. 373-376 ◽  
Author(s):  
Yoshihiko Hirotani ◽  
Ayae Doi ◽  
Tomoki Takahashi ◽  
Hanako Umezawa ◽  
Yoko Urashima ◽  
...  
Keyword(s):  
Liver Disease ◽  
Herbal Medicine ◽  
Fatty Liver ◽  
Rat Model ◽  
Fatty Liver Disease ◽  
Protective Effects ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals Effect of Chinese Herbal Medicine Mixture 919 Syrup on Regulation of the Ghrelin Pathway and Intestinal Microbiota in Rats With Non-alcoholic Fatty Liver Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Manman Chen ◽  
Jingwei Xing ◽  
Danqing Pan ◽  
Pengfei Gao
Keyword(s):  
Body Weight ◽  
Liver Disease ◽  
Herbal Medicine ◽  
Fatty Liver ◽  
Intestinal Microbiota ◽  
Feed Intake ◽  
Fatty Liver Disease ◽  
Therapeutic Drug ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

As a manifestation of metabolic syndrome in the liver, non-alcoholic fatty liver disease (NAFLD) has become the top cause of liver disease in many countries. Recent studies have shown that intestinal microbiota disorder plays an important role in the occurrence and development of NAFLD and that regulating intestinal microbiota provides a new option for NAFLD treatment. In addition, research indicates that risk of NAFLD increases as body mass index rises, and interventions that reduce body weight and change diet can help to lower the incidence of NAFLD. Studies have found that 919 syrup may effectively treat NAFLD in rats by improving liver function and lipid metabolism and regulating body weight and feed intake, however, its potential toxicity and the specific mechanism by which it controls this disease require further exploration. This study assesses both the toxicity of 919 syrup and its regulatory effect on the appetite-related Ghrelin pathway and intestinal microbiota of rats with NAFLD. Results indicate that 919 syrup has no obvious side-effects on body weight, feed intake, blood glucose level, hepatorenal function, and liver tissue structure of normal rats. Moreover, 919 syrup can reverse abnormal changes to expression of Ghrelin pathway genes related to appetite in both the brain and stomach and repair alterations to the intestinal microbiota in rats with NAFLD. This herbal medicine is a safe and promising therapeutic drug for the treatment of NAFLD.

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