scholarly journals The relationship of lymphatic vessel density, lymphovascular invasion, and lymph node metastasis in breast cancer: a systematic review and meta-analysis

Oncotarget ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 2863-2873 ◽  
Author(s):  
Song Zhang ◽  
Dong Zhang ◽  
Shanhong Yi ◽  
Mingfu Gong ◽  
Caibao Lu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Lymph Node ◽  
Lymphatic Vessel ◽  
Lymphovascular Invasion ◽  
Meta Analysis ◽  
Lymphatic Vessel Density ◽  
Node Metastasis ◽  
Relationship Of ◽  
The Relationship

scholarly journals Intratumoral and peritumoral lymphatic vessel density both correlate with lymph node metastasis in breast cancer

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Song Zhang ◽  
Shanhong Yi ◽  
Dong Zhang ◽  
Mingfu Gong ◽  
Yuanqing Cai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Lymphatic Vessel ◽  
Vessel Density ◽  
Lymphatic Vessel Density ◽  
Node Metastasis

scholarly journals LncRNA NORAD as a Novel Predictor of Lymph Node Metastasis and Prognosis in Solid Tumors: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 19 ◽  
pp. 153303382096358
Author(s):  
Tao Ye ◽  
Zhangqun Ye
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Meta Analysis ◽  
Tumor Grade ◽  
Node Metastasis ◽  
Human Cancers ◽  
Non Coding Rna ◽  
Relationship Of ◽  
The Relationship ◽  
Review Manager

Background: Non-coding RNA-activated by DNA damage (NORAD), a novel identified lncRNA, was found to be aberrantly expressed in various types of cancer. This meta-analysis was performed to evaluate the value of lncRNA NORAD as a prognostic biomarker in human cancers. Methods: We searched PubMed, Web of Science, PMC, and Embase databases thoroughly for eligible literatures. Studies which explored the relationship of lncRNA NORAD expression with clinical outcomes in human cancers were included in our meta-analysis. Review Manager version 5.3 and Stata SE 12.0 were used to perform the data analyses. Results: Our meta-analysis results indicated that cancer patients with high lncRNA NORAD expression tended to have unfavorable overall survival (OS) (HR = 1.67; 95% CI, 1.44-1.95; P < 0.00001). Moreover, elevated lncRNA NORAD expression showed a significant relationship with poor tumor grade (OR = 1.61; 95% CI, 1.01-2.56; P = 0.05) and more lymph node metastasis (LNM) (OR = 2.66; 95% CI, 1.60-4.43; P = 0.0002). Conclusions: LncRNA NORAD could serve as a valuable biomarker to predict poor prognosis and LNM in various human tumors.

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