scholarly journals Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells

Oncotarget ◽  
2016 ◽  
Vol 7 (45) ◽  
pp. 73607-73617 ◽  
Author(s):  
Li Zhang ◽  
Shudai Lin ◽  
Lilong An ◽  
Jinge Ma ◽  
Fengfang Qiu ◽  
...  
Keyword(s):  
Antisense Transcript ◽  
Natural Antisense Transcript ◽  
Lmh Cells

scholarly journals Natural Antisense Transcript PEBP1P3 Regulates the RNA Expression, DNA Methylation and Histone Modification of CD45 Gene

Genes ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 759
Author(s):  
Zhongjing Su ◽  
Guangyu Liu ◽  
Bin Zhang ◽  
Ze Lin ◽  
Dongyang Huang
Keyword(s):  
Dna Methylation ◽  
Alternative Splicing ◽  
Histone Modification ◽  
Antisense Rna ◽  
Noncoding Rna ◽  
Antisense Transcript ◽  
Natural Antisense Transcript ◽  
Regulation Of Expression ◽  
Splicing Isoforms ◽  
Intron 2

The leukocyte common antigen CD45 is a transmembrane phosphatase expressed on all nucleated hemopoietic cells, and the expression levels of its splicing isoforms are closely related to the development and function of lymphocytes. PEBP1P3 is a natural antisense transcript from the opposite strand of CD45 intron 2 and is predicted to be a noncoding RNA. The genotype-tissue expression and quantitative PCR data suggested that PEBP1P3 might be involved in the regulation of expression of CD45 splicing isoforms. To explore the regulatory mechanism of PEBP1P3 in CD45 expression, DNA methylation and histone modification were detected by bisulfate sequencing PCR and chromatin immunoprecipitation assays, respectively. The results showed that after the antisense RNA PEBP1P3 was knocked down by RNA interference, the DNA methylation of CD45 intron 2 was decreased and histone H3K9 and H3K36 trimethylation at the alternative splicing exons of CD45 DNA was increased. Knockdown of PEBP1P3 also increased the binding levels of chromatin conformation organizer CTCF at intron 2 and the alternative splicing exons of CD45. The present results indicate that the natural antisense RNA PEBP1P3 regulated the alternative splicing of CD45 RNA, and that might be correlated with the regulation of histone modification and DNA methylation.

Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3

2016 ◽  
Vol 43 (5) ◽  
pp. 427-436 ◽  
Author(s):  
Jiabing Sun ◽  
Xuming Wang ◽  
Chunjiang Fu ◽  
Xiaoyu Wang ◽  
Jilong Zou ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Antisense Transcript ◽  
Natural Antisense Transcript

P4-264: A GENE THERAPY APPROACH FOR REDUCTION OF TAU BY TAU LONG NON-CODING RNA GENE (MAPT-AS1 ) NATURAL ANTISENSE TRANSCRIPT

2006 ◽  
Vol 14 (7S_Part_29) ◽  
pp. P1547-P1548
Author(s):  
Rohan de Silva ◽  
Justyna Zareba-Paslawska ◽  
Filipa Almeida ◽  
Per Svenningsson ◽  
Tom Warner ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Antisense Transcript ◽  
Natural Antisense Transcript ◽  
Therapy Approach ◽  
Gene Therapy Approach ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals PTB-AS, a Novel Natural Antisense Transcript, Promotes Glioma Progression by Improving PTBP1 mRNA Stability with SND1

2019 ◽  
Vol 27 (9) ◽  
pp. 1621-1637 ◽  
Author(s):  
Liyuan Zhu ◽  
Qunfang Wei ◽  
Yingjiao Qi ◽  
Xiangbin Ruan ◽  
Fan Wu ◽  
...  
Keyword(s):  
Mrna Stability ◽  
Antisense Transcript ◽  
Natural Antisense Transcript ◽  
Glioma Progression

scholarly journals Natural antisense transcript stabilizes inducible nitric oxide synthase messenger RNA in rat hepatocytes

Hepatology ◽  
2007 ◽  
Vol 47 (2) ◽  
pp. 686-697 ◽  
Author(s):  
Kosuke Matsui ◽  
Mikio Nishizawa ◽  
Takashi Ozaki ◽  
Tominori Kimura ◽  
Iwao Hashimoto ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Messenger Rna ◽  
Antisense Transcript ◽  
Rat Hepatocytes ◽  
Natural Antisense Transcript ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

The effect of temperature on Natural Antisense Transcript (NAT) expression in Aspergillus flavus

2008 ◽  
Vol 54 (5) ◽  
pp. 241-269 ◽  
Author(s):  
Carrie A. Smith ◽  
Dominique Robertson ◽  
Bethan Yates ◽  
Dahlia M. Nielsen ◽  
Doug Brown ◽  
...  
Keyword(s):  
Aspergillus Flavus ◽  
Antisense Transcript ◽  
Effect Of Temperature ◽  
Natural Antisense Transcript
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