scholarly journals Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instabilityin vivo

Oncotarget ◽  
2016 ◽  
Vol 7 (33) ◽  
pp. 52729-52739 ◽  
Author(s):  
Jing-Jing Yang ◽  
Peng Li ◽  
Fu Wang ◽  
Wen-Jing Liang ◽  
Hui Ma ◽  
...  
Keyword(s):  
Atherosclerotic Plaque ◽  
Activator Protein ◽  
Plaque Growth ◽  
Activator Protein 2

Expression of Activator Protein 2 in Prostate Cancer Is Related to Tumor Differentiation and Cell Proliferation

2000 ◽  
Vol 37 (5) ◽  
pp. 573-578 ◽  
Author(s):  
P. Lipponen ◽  
S. Aaltomaa ◽  
J. Kellokoski ◽  
M. Ala-Opas ◽  
V.-M. Kosma
Keyword(s):  
Prostate Cancer ◽  
Cell Proliferation ◽  
Tumor Differentiation ◽  
Activator Protein ◽  
Activator Protein 2

Induction of cyclooxygenase-2 by staurosporine through the activation of nuclear factor for IL-6 (NF-IL6) and activator protein 2 (AP2) in an osteoblast-like cell line

2002 ◽  
Vol 64 (2) ◽  
pp. 177-184 ◽  
Author(s):  
Chiu-Ya Wang ◽  
Huey-Jing Lei ◽  
Chi-Ying Fred Huang ◽  
Zhongjian Zhang ◽  
Anil B Mukherjee ◽  
...  
Keyword(s):  
Cell Line ◽  
Cyclooxygenase 2 ◽  
Nuclear Factor ◽  
Activator Protein ◽  
Activator Protein 2

Human Carotid Atherosclerotic Plaque Growth Function and Progression Simulation Using Meshless GFD and Statistical Methods Based on Multi-Year In Vivo MRI

2008 ◽  
Author(s):  
Chun Yang ◽  
Joseph D. Petruccelli ◽  
Zhongzhao Teng ◽  
Chun Yuan ◽  
Gador Canton ◽  
...  
Keyword(s):  
Atherosclerotic Plaque ◽  
Wall Thickness ◽  
Vessel Wall ◽  
Plaque Rupture ◽  
Patient Specific ◽  
Tracking Data ◽  
Plaque Progression ◽  
Vessel Wall Thickness ◽  
Plaque Growth

Atherosclerotic plaque rupture and progression have been the focus of intensive investigations in recent years. The mechanisms governing plaque progression and rupture process are not well understood. Using computational models based on patient-specific multi-year in vivo MRI data, our recent results indicated that 18 out of 21 patients studied showed significant negative correlation between plaque progression measured by vessel wall thickness increase (WTI) and plaque wall (structural) stress (PWS) [1]. In this paper, a computational procedure based on meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data was introduced to simulate plaque progression. Participating patients were scanned three times (T1, T2, and T3, at intervals of approximately 18 months) to obtain plaque progression data. Vessel wall thickness (WT) changes were used as the measure for plaque progression. Starting from T2 plaque geometry, plaque progression was simulated by solving the solid model and adjusting wall thickness using plaque growth functions iteratively until time T3 is reached. Numerically simulated plaque progression showed very good agreement with actual plaque geometry at T3 given by MRI data. We believe this is the first time plaque progression simulation results based on multi-year patient-tracking data are reported. Multi-year tracking data and MRI-based progression simulation add time dimension to plaque vulnerability assessment and will improve prediction accuracy.

Activator protein-2 regulates human placental lactogen gene expression

2000 ◽  
Vol 160 (1-2) ◽  
pp. 183-192 ◽  
Author(s):  
B.D Richardson ◽  
R.A Langland ◽  
C.J Bachurski ◽  
R.G Richards ◽  
C.A Kessler ◽  
...  
Keyword(s):  
Gene Expression ◽  
Placental Lactogen ◽  
Human Placental Lactogen ◽  
Activator Protein ◽  
Activator Protein 2

scholarly journals Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells

BMC Cancer ◽  
2009 ◽  
Vol 9 (1) ◽  
Author(s):  
He Ailan ◽  
Xiao Xiangwen ◽  
Ren Daolong ◽  
Gan Lu ◽  
Ding Xiaofeng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Transcription Factor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Target Genes ◽  
Activator Protein ◽  
Activator Protein 2

scholarly journals Yin Yang 1 Cooperates with Activator Protein 2 to StimulateERBB2Gene Expression in Mammary Cancer Cells

2005 ◽  
Vol 280 (26) ◽  
pp. 24428-24434 ◽  
Author(s):  
Dominique Y. Begon ◽  
Laurence Delacroix ◽  
Douglas Vernimmen ◽  
Pascale Jackers ◽  
Rosita Winkler
Keyword(s):  
Cancer Cells ◽  
Mammary Cancer ◽  
Activator Protein ◽  
Yin Yang 1 ◽  
Yin Yang ◽  
Mammary Cancer Cells ◽  
Activator Protein 2
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