scholarly journals Risk of arterial stiffness according to metabolically healthy obese phenotype: a combined cross-sectional and longitudinal study in kailuan cohort

Aging ◽  
2021 ◽  
Author(s):  
Anxin Wang ◽  
Yu Wang ◽  
Yingting Zuo ◽  
Xue Tian ◽  
Shuohua Chen ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Arterial Stiffness ◽  
Cross Sectional ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Risk of Arterial Stiffness According to Metabolically Healthy Obese Phenotype: A Combined Cross-Sectional and Longitudinal Study in Kailuan Cohort

2020 ◽  
Author(s):  
Anxin Wang ◽  
Yu Wang ◽  
Yingting Zuo ◽  
Xue Tian ◽  
Shuohua Chen ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Health Status ◽  
Arterial Stiffness ◽  
Metabolic Health ◽  
Cross Sectional ◽  
Metabolically Healthy Obese ◽  
Increased Risk ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Healthy Participants

Abstract BackgroundTo investigate the risk of incident arterial stiffness according to metabolically healthy obese (MHO) phenotype in Chinese population.Materials and methodsThe Kailuan study is an ongoing prospective cohort study, 37,180 participants with at least one-time measurement of branchial-ankle pulse wave velocity (baPWV) were included in the cross-sectional analysis, and 16,236 participants with repeated measurement of baPWV during the follow-ups were included in the longitudinal study from March 1, 2010, to January 31, 2020. Cross-classification of body mass index (BMI) categories and metabolic health status created six groups. Linear and logistic regression analyses were used to assess the association between BMI-metabolic status phenotypes and baPWV in mono-factor and multi-factor models. ResultsThe results of cross-sectional and longitudinal investigation were basically the same, as the abnormality of baPWV increased with BMI categories in metabolically healthy participants, while the increasing tendency disappeared in metabolically unhealthy participants. A 1.6-fold, 2.8-fold increased risk for the new occurrence of arterial stiffness were documented in MHO and metabolically unhealthy obese participants compared to metabolically healthy normal weight controls in the fully adjusted model. Further stratified analysis shown that metabolic health status was an interaction factor between BMI and arterial stiffness in either study population (P<0.0001 for cross-sectional study and P=0.0003 for longitudinal study).ConclusionsMetabolic health status and BMI categories contribute to the progression of arterial stiffness, while BMI is positively associated with arterial stiffness only in metabolically healthy participants. Moreover, MHO is an intermediate stage between metabolically healthy and unhealthy status.Trial registration: ChiCTR-TNRC-11001489. Registered 24 August 2011 - Retrospectively registered, http://www.chictr.org.cn/showprojen.aspx?proj=8050

Prevalence of metabolically healthy obese phenotype and associated factors in South American overweight adolescents: A cross-sectional study

Nutrition ◽  
2019 ◽  
Vol 60 ◽  
pp. 19-24 ◽  
Author(s):  
Jane Maria Remor ◽  
Wendell Arthur Lopes ◽  
João Carlos Locateli ◽  
Ronano Pereira Oliveira ◽  
Caroline Ferraz Simões ◽  
...  
Keyword(s):  
Associated Factors ◽  
Cross Sectional Study ◽  
South American ◽  
Sectional Study ◽  
Cross Sectional ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Overweight Adolescents ◽  
Obese Phenotype

scholarly journals OR20-4 NMRI-metabolomics Variables Associated With The Metabolically-healthy Obese Phenotype And The Transitions Between Metabolically-healthy And Unhealthy Obesity Phenotypes.

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Arsenio Vargas-Vazquez ◽  
Omar Bello-Chavolla ◽  
Neftali Antonio Villa ◽  
Donaji Veronica Gomez-Velazquez ◽  
Carlos Aguilar Salinas
Keyword(s):  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

scholarly journals Diabetes and Cardiovascular Disease Outcomes in the Metabolically Healthy Obese Phenotype: A cohort study

Diabetes Care ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 2388-2394 ◽  
Author(s):  
S. L. Appleton ◽  
C. J. Seaborn ◽  
R. Visvanathan ◽  
C. L. Hill ◽  
T. K. Gill ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cohort Study ◽  
Metabolically Healthy Obese ◽  
Disease Outcomes ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

scholarly journals A metabolically healthy obese phenotype in hispanic participants in the IRAS family study

Obesity ◽  
2013 ◽  
Vol 21 (11) ◽  
pp. 2303-2309 ◽  
Author(s):  
Xanthia F. Samaropoulos ◽  
Kristen G. Hairston ◽  
Andrea Anderson ◽  
Steven M. Haffner ◽  
Carlos Lorenzo ◽  
...  
Keyword(s):  
Family Study ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Prevalence and characteristics of the metabolically healthy obese phenotype in children and adolescents in a Mexican state

2020 ◽  
Vol 67 (10) ◽  
pp. 625-635
Author(s):  
María Luisa Pizano-Zárate ◽  
Gabriel Horta-Baas ◽  
Jorge A. Nuñez-Hernández ◽  
Álvaro J. Montiel-Jarquín ◽  
Maricruz Tolentino-Dolores ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Metabolically Healthy Obese ◽  
Mexican State ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Preclinical signs of liver and cardiac damage in youth with metabolically healthy obese phenotype

2018 ◽  
Vol 28 (12) ◽  
pp. 1230-1236 ◽  
Author(s):  
P. Di Bonito ◽  
E. Miraglia del Giudice ◽  
C. Chiesa ◽  
M.R. Licenziati ◽  
M. Manco ◽  
...  
Keyword(s):  
Cardiac Damage ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Preserved insulin sensitivity predicts metabolically healthy obese phenotype in children and adolescents

2015 ◽  
Vol 174 (12) ◽  
pp. 1649-1655 ◽  
Author(s):  
Rade Vukovic ◽  
Tatjana Milenkovic ◽  
Katarina Mitrovic ◽  
Sladjana Todorovic ◽  
Ljiljana Plavsic ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Children And Adolescents ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype
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