scholarly journals Diabetes and Cardiovascular Disease Outcomes in the Metabolically Healthy Obese Phenotype: A cohort study

Diabetes Care ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 2388-2394 ◽  
Author(s):  
S. L. Appleton ◽  
C. J. Seaborn ◽  
R. Visvanathan ◽  
C. L. Hill ◽  
T. K. Gill ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cohort Study ◽  
Metabolically Healthy Obese ◽  
Disease Outcomes ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

scholarly journals OR20-4 NMRI-metabolomics Variables Associated With The Metabolically-healthy Obese Phenotype And The Transitions Between Metabolically-healthy And Unhealthy Obesity Phenotypes.

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Arsenio Vargas-Vazquez ◽  
Omar Bello-Chavolla ◽  
Neftali Antonio Villa ◽  
Donaji Veronica Gomez-Velazquez ◽  
Carlos Aguilar Salinas
Keyword(s):  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

scholarly journals A metabolically healthy obese phenotype in hispanic participants in the IRAS family study

Obesity ◽  
2013 ◽  
Vol 21 (11) ◽  
pp. 2303-2309 ◽  
Author(s):  
Xanthia F. Samaropoulos ◽  
Kristen G. Hairston ◽  
Andrea Anderson ◽  
Steven M. Haffner ◽  
Carlos Lorenzo ◽  
...  
Keyword(s):  
Family Study ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Prevalence and characteristics of the metabolically healthy obese phenotype in children and adolescents in a Mexican state

2020 ◽  
Vol 67 (10) ◽  
pp. 625-635
Author(s):  
María Luisa Pizano-Zárate ◽  
Gabriel Horta-Baas ◽  
Jorge A. Nuñez-Hernández ◽  
Álvaro J. Montiel-Jarquín ◽  
Maricruz Tolentino-Dolores ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Metabolically Healthy Obese ◽  
Mexican State ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype

Abstract 163: The Prevalence of the Metabolically Healthy Obese Phenotype in an Aging Population and its Association with Subclinical Cardiovascular Disease: The Brazilian Study on Healthy Aging

2013 ◽  
Vol 33 (suppl_1) ◽  
Author(s):  
Lara L Roberson ◽  
Shozab A Siddiqui ◽  
Michael J Blaha ◽  
Arthur A Agatston ◽  
Roger S Blumenthal ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Waist Circumference ◽  
Healthy Aging ◽  
Subclinical Atherosclerosis ◽  
Aging Population ◽  
Normal Weight ◽  
Metabolically Healthy Obese ◽  
Subclinical Cardiovascular Disease ◽  
Healthy Obese ◽  
Metabolically Healthy

BACKGROUND Obese and overweight individuals have been shown to be at higher risk of CVD events than normal weight individuals. Current literature has elucidated a new phenotype, Metabolically Healthy Obese (MHO), with risks of CVD similar to that of normal weight individuals. Few studies have examined the MHO phenotype in an aging population, especially in association with subclinical cardiovascular disease. METHODS The cross sectional study population consisted of 208 individuals (79% Female), age 80 and older (mean age 84±4, range 80-102). Anthropometrics & biochemical parameters were measured. The Adult Treatment Panel definition of metabolic syndrome (MetS), excluding waist circumference, criteria was used to define metabolically healthy (<3 MetS components) versus unhealthy. A combination of BMI and waist circumference were used to define normal weight and overweight/obese. Multidetector-row cardiac CT for coronary artery calcium score (CACS) was used to detect subclinical atherosclerosis. High reactive C reactive protein (hs-CRP) was measured to assess degree of underlying inflammation. RESULTS The prevalence of MHO defined by BMI≥25 kg/m2 &/or waist circumference >88cm in women, >102cm in men & having 3mg/dl, Uric Acid >6 mg/dl (p=NS). Gender, total cholesterol, HDL, LDL, triglycerides, and SBP was significantly associated with MHO (p<0.05). CONCLUSIONS Our results suggest that the MHO phenotype is still seen in octogenarians, but at lower rates than in the general population suggesting MHO may not simply be an intermediary stage, driven by length of spent in the obese state. Those with this phenotype tended to have lower triglycerides, higher HDL, and lower body fat % than their metabolically at risk obese counterparts (p<0.05), however, degree of subclinical CVD was not different. Further studies are needed to explore the related risk of CVD among MHO octogenarians.

Preclinical signs of liver and cardiac damage in youth with metabolically healthy obese phenotype

2018 ◽  
Vol 28 (12) ◽  
pp. 1230-1236 ◽  
Author(s):  
P. Di Bonito ◽  
E. Miraglia del Giudice ◽  
C. Chiesa ◽  
M.R. Licenziati ◽  
M. Manco ◽  
...  
Keyword(s):  
Cardiac Damage ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Obese Phenotype
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