scholarly journals High pulse pressure is a risk factor for prodromal Alzheimer’s disease: a longitudinal study

Aging ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 18221-18237
Author(s):  
Wen-Yan Shi ◽  
Zuo-Teng Wang ◽  
Fu-Rong Sun ◽  
Ya-Hui Ma ◽  
Wei Xu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Longitudinal Study ◽  
Pulse Pressure ◽  
High Pulse Pressure ◽  
Prodromal Alzheimer’S Disease ◽  
High Pulse

P4-048: Pulse pressure, dementia and Alzheimer's disease: The Oxford Project to Investigate Memory and Ageing (OPTIMA) Longitudinal Study

2008 ◽  
Vol 4 ◽  
pp. T682-T682
Author(s):  
George Razay ◽  
Jonathon Williams ◽  
Elizabeth King ◽  
A. David Smith ◽  
Gordon Wilcock
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Longitudinal Study ◽  
Pulse Pressure

scholarly journals Late-life obesity is a protective factor for prodromal Alzheimer’s disease: a longitudinal study

Aging ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 2005-2017 ◽  
Author(s):  
Zhen Sun ◽  
Zuo-Teng Wang ◽  
Fu-Rong Sun ◽  
Xue-Ning Shen ◽  
Wei Xu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Longitudinal Study ◽  
Protective Factor ◽  
Late Life ◽  
Prodromal Alzheimer’S Disease

Repurposing Antihypertensive Drugs for the Management of Alzheimer’s Disease

2020 ◽  
Vol 27 ◽  
Author(s):  
Keng Yoon Yeong ◽  
Christine Law
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Literature Review ◽  
Neurodegenerative Disorder ◽  
Antihypertensive Drugs ◽  
Future Prospects ◽  
Short Term

Alzheimer’s disease (AD) is a neurodegenerative disorder that has affected millions of people worldwide. However, currently there is no treatment to cure the disease. The AD drugs available in the market only manage the disease symptomatically and the effects are usually short-term. Thus, there is a need to look at alternatives AD therapies. Mid-life hypertension has not only been recognised as a risk factor for AD, but its relation with AD has also been well established. Thus, antihypertensives are postulated to be beneficial in managing AD. This literature review aims to shed some light on the potential of repurposing antihypertensives to treat AD, considering recent updates. Four classes of antihypertensives, as well as their potential limitations and future prospects in being utilised as AD therapeutics are discussed in this review.

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