scholarly journals Dual-Light Photodynamic Therapy Effectively Eliminates Streptococcus Oralis Biofilms

2021 ◽  
Vol 24 ◽  
pp. 484-487
Author(s):  
Jessica Hentilä ◽  
Noora Laakamaa ◽  
Timo Sorsa ◽  
Jukka Meurman ◽  
Hanna Välimaa ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Antibacterial Effect ◽  
Oral Microbiota ◽  
Antibacterial Efficacy ◽  
Radiant Exposure ◽  
Streptococcus Oralis ◽  
Streptococcal Species ◽  
Neutropenic Patients ◽  
Antibacterial Potential

Purpose: During cancer treatment, oral mucositis due to radiotherapy or chemotherapy often leads to disruption of the oral mucosa, enabling microbes to invade bloodstream. Viridans streptococcal species are part of the healthy oral microbiota but can be frequently isolated from the blood of neutropenic patients.  We have previously shown the antibacterial efficacy of dual-light, the combination of antibacterial blue light (aBL) and indocyanine green photodynamic therapy (aPDT). Methods: Here, we investigated the dual-light antibacterial action against four-day Streptococcus oralis biofilm. In addition, while keeping the total radiant exposure constant at 100J/cm2, we investigated the effect of changing the different relative light energies of aBL and aPDT to the antibacterial potential. Results: The dual-light had a significant antibacterial effect in all the tested combinations. Conclusion: Dual-light can be used as an effective disinfectant against S. oralis biofilm.  

“Stealth” dendrimers with encapsulation of indocyanine green for photothermal and photodynamic therapy of cancer

2021 ◽  
Vol 600 ◽  
pp. 120502 ◽  
Author(s):  
Tianming Cui ◽  
Shukai Li ◽  
Shengfu Chen ◽  
Ying Liang ◽  
Haotian Sun ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Photodynamic Therapy Of Cancer

scholarly journals Antibacterial Effect of Amino Acid–Silver Complex Loaded Montmorillonite Incorporated in Dental Acrylic Resin

Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1442
Author(s):  
Kumiko Yoshihara ◽  
Noriyuki Nagaoka ◽  
Aya Umeno ◽  
Akinari Sonoda ◽  
Hideki Obika ◽  
...  
Keyword(s):  
Amino Acid ◽  
Antibacterial Agents ◽  
Antibacterial Effect ◽  
Dental Materials ◽  
Silver Ions ◽  
Acrylic Resin ◽  
Chloride Ions ◽  
Antibacterial Efficacy ◽  
Growth Measurement ◽  
Dental Acrylic

Several dental materials contain silver for antibacterial effect, however the effect is relatively low. The reason for the lower antibacterial efficacy of silver is considered to be the fact that silver ions bind to chloride ions in saliva. To develop new effective silver antibacterial agents that can be useful in the mouth, we synthesized two novel amino acid (methionine or histidine)–silver complexes (Met or His–Ag) loaded with montmorillonite (Mont) and analyzed their antibacterial efficacy. At first the complexes were characterized using nuclear magnetic resonance (NMR), and amino acid–Ag complex-loaded Mont (amino acid–Ag–Mont) were characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The antibacterial efficacy of these materials in dental acrylic resin was then investigated by bacterial growth measurement using a spectrophotometer. As controls, commercially available silver-loaded zeolite and silver-zirconium phosphate were also tested. Dental acrylic resin incorporating His–Ag–Mont strongly inhibited Streptococcus mutans growth. This was explained by the fact that His-Ag complex revealed the highest amounts of silver ions in the presence of chloride. The structure of the amino acid–Ag complexes affected the silver ion presence in chloride and the antibacterial efficacy. His–Ag–Mont might be used as antibacterial agents for dental materials.

Optical profile: A key determinant of antibacterial efficacy of photodynamic therapy in dentistry

2021 ◽  
pp. 102461
Author(s):  
Chuan‐Tsung Su ◽  
Chun‐Ju Chen ◽  
Chung‐Ming Chen ◽  
Chun‐Cheng Chen ◽  
Shih‐Hsin Ma ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Antibacterial Efficacy

Choriocapillaris photodynamic therapy using indocyanine green

2001 ◽  
Vol 132 (4) ◽  
pp. 557-565 ◽  
Author(s):  
Rogério A Costa ◽  
Michel E Farah ◽  
Edna Freymüller ◽  
Paulo H Morales ◽  
Ricardo Smith ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green

scholarly journals Antibacterial Effect of Carvacrol and Coconut Oil on Selected Pathogenic Bacteria

2018 ◽  
Vol 49 (1) ◽  
pp. 46-52 ◽  
Author(s):  
M. Božik ◽  
P. Hovorková ◽  
P. Klouček
Keyword(s):  
Essential Oils ◽  
Lauric Acid ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Antibacterial Effect ◽  
Cocos Nucifera ◽  
Coconut Oil ◽  
High Concentration ◽  
Enterococcus Cecorum ◽  
Antibacterial Potential

AbstractEssential oils play a prominent role as flavouring agents and fragrances in the food and perfume industries. Carvacrol is a major component of various essential oils, such as oregano and thyme oils, and is responsible for their antimicrobial activity. Lauric acid is a medium-chain fatty acid (MCFA) with a high antibacterial potential. Both carvacrol and MCFAs have been used empirically as antimicrobial agents. Here, we tested the inhibitory properties of carvacrol and coconut (Cocos nuciferaL.) oil containing a high percentage of MCFAs against 5 harmful bacterial pathogens:Escherichia coli, SalmonellaEnteritidis,Staphylococcus aureus, Listeria monocytogenes, andEnterococcus cecorum. Gas chromatography (GC-FID) analysis of coconut oil showed a high concentration of lauric acid (41%). Microdilution antimicrobial assays showed that the combination of carvacrol and coconut oil had a stronger antibacterial effect against all tested bacteria than both agents separately. We conclude that carvacrol could significantly improve the antibacterial effect of coconut oil.

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