scholarly journals Clay and Polymer-Based Composites Applied to Drug Release: A Scientific and Technological Prospection

2017 ◽  
Vol 20 ◽  
pp. 115 ◽  
Author(s):  
Lyghia Maria Araújo Meirelles ◽  
Fernanda Nervo Raffin

There has been a growing trend in recent years for the development of hybrid materials, called composites, based on clay and polymers, whose innovative properties render them attractive for drug release. The objective of this manuscript was to conduct a review of original articles on this topic published over the last decade and of the body of patents related to these carriers. A scientific prospection was carried out spanning the period from 2005 to 2015 on the Web of Science database. The technological prospection encompassed the United States Patent and Trademark Office, the European Patent Office, the World International Patent Office and the National Institute of Industrial Property databases, filtering patents with the code A61K. The survey revealed a rise in the number of publications over the past decade, confirming the potential of these hybrids for use in pharmaceutical technology. Through interaction between polymer and clay, the mechanical and thermal properties of composites are enhanced, promoting stable, controlled drugs release in biological media. The most cited clays analyzed in the articles was montmorillonite, owing to its high surface area and capacity for ion exchange. The polymeric part is commonly obtained by copolymerization, particularly using acrylate derivatives. The hybrid materials are obtained mainly in particulate form on a nanometric scale, attaining a modified release profile often sensitive to stimuli in the media. A low number of patents related to the topic were found. The World International Patent Office had the highest number of lodged patents, while Japan was the country which published the most patents. A need to broaden the application of this technology to include more therapeutic classes was identified. Moreover, the absence of regulation of nanomaterials might explain the disparity between scientific and technological output. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

2021 ◽  
Vol 10 (14) ◽  
pp. e333101422076
Author(s):  
Nathália Andrezza Carvalho de Souza ◽  
Victória Laysna dos Anjos Santos ◽  
Tarcísio Cícero de Lima Araújo ◽  
Pedrita Alves Sampaio ◽  
Renata Rivelli Menezes de Souza ◽  
...  

The genus Mikania (Asteraceae) comprises about 450 species of these, 203 are found in Brazil and present several chemical and biological activities. Considering the variety of species and their therapeutic properties, the present study aimed to perform technological prospecting of this genus, since this approach aims to contribute to technological, scientific and innovation research. For this purpose, the patent documents were analyzed, regarding the applicant countries, year of filing and the international classification of patents of the genus Mikania. The search was conducted in the databases World Intellectual Property Organization (WIPO), European Patent Office (EPO) and the National Institute of Industrial Property (INPI) in October 2020, using the descriptor “Mikania”; present in the title and/or abstract in addition, documents that included medicinal approaches were selected. Thus, taking into consideration the filing countries, Japan, Brazil and the United States led the patent deposits, with the first document filed in 1991 and the largest number of applications in the years 2000 and 2010. The data concerning the international patent classification are concentrated in subclass A61K, which deals with preparations for medical, dental or hygienic purposes. These results demonstrated the therapeutic and technological potential of the Mikania species and thus which can be evidenced the potential of this study.


2019 ◽  
Author(s):  
khoiriazulhijah

AbstractPerbedaan sistem hukum perlindungan lingkup paten di berbagai Negara,tidak hanya mengimpor investasi baru namun juga menentukan proses transfer teknologi suatu Negara. Perlindungan yang meluas menyebabkan transfer teknologi tidak mudah walaupun kurangnya perlindungan karena pemilik paten mengalami kerugian.kedua perbedaan niat tersebut menghasilkan perlunya studi komperatif tentang cangkupan perlindungan paten di Negara-negara. Ada dua masalah yang harus dijajaki, pertama apa perbedaan dan kesamaan cakupan perlindungan paten dalam peraturan negara dan yang kedua bagaimana sistem hukum mempengaruhi kejadian yang berbeda? A.INTRODUCTIONPerkembangan Teknologi suatu Negara,tidak lepas dari aspek perlindungan hak paten yang berlaku pada Negara tersebut. Negara jepang sebagai contoh, adalah Negara yang dikenal paling maju teknologinya.Semula Negara ini banyak mencontoh teknologi Negara-negara Eropa dan Amerika, namun dalam perkembangan yang kita ketahui akhir-akhir ini justru jepanglah yang menjadi kiblat dari Negara-negara lain termasuk Eropa dan Amerika.B.CONTENT1.Perlindungan paten di Negara-Negara Eropa Konvensi Paten Eropa, Undang-Undang Paten Jerman, Amerika Serikat, dan Jepang, dalam makalah “Comparative Study on the Japanese, the United States and the European Patent Systems”, oleh Japan Patent Office Asia-Pacific Industrial Property Center di Jepang belum lama ini (tahun 2001), bila ditelaah banyak mengungkap persamaan/perbedaan perlindungan paten negara-negara tersebut. Beberapa pasal konvensi dan undang-undang negara dimaksud, memperkaya isi tulisan ini.C.CONCLUSIONPerlindungan paten baik bagi negara-negara Eropa yang mengikuti Konvensi Paten Eropa, Jepang maupun Indonesia memiliki persamaan dalam memberikan perlindungan paten berdasarkan prinsip first-to-file, yang berbeda dengan Amerika Serikat berdasarkan prinsip first-to-invent. Sekalipun Amerika Serikat menggunakan prinsip first-to-invent, tetapi Amerika Serikat juga mengatur syarat perlindungan sebagaimana negara-negara Eropa, Jepang dan Indonesia yang berupa penemuan baru, mengandung langkah inventif, dan dapat diterapkan dalam industri. D.DISCUSSIONIndonesia yang sekarang ini dalam undang-undangnya masih mengatur secara umum lingkup perlindungan hak paten, disarankan mengikuti prilaku hakim pengadilan Jepang yang mengadopsi doktrin file wrapper estoppel dan equivalent sebagaimana berlaku di Amerika Serikat. Hal ini didasarkan pertimbangan bahwa doktrin yang dimaksud memberikan keseimbangan pada perlindungan pemegang paten, di samping perlindungan kepentingan negara dalam proses alih teknologi. E.REFERENCE [1]O. M. Febriani and A. S. Putra, “Sistem Informasi Monitoring Inventori Barang Pada Balai Riset Standardisasi Industri Bandar Lampung,” J. Inform., vol. 13, no. 1, pp. 90–98, 2014.[2]A. S. Putra, “Paperplain: Execution Fundamental Create Application With Borland Delphi 7.0 University Of Mitra Indonesia,” 2018.[3]A. S. Putra, “2018 Artikel Struktur Data, Audit Dan Jaringan Komputer,” 2018.


2021 ◽  
Author(s):  
Fabio Monteiro dos Santos ◽  
Heleno José Costa Bezerra Netto ◽  
Ricardo Carvalho Rodrigues

The right to appeal exists as a response to the two main characteristics of every human being. The first refers to the attitude of not settling for adverse decisions, which leads people to seek instruments to remediate these decisions, while the second is the possibility that every human being has to make mistakes and the need to correct these mistakes in decision-making acts that may have been mistaken. Therefore, an appeal is an instrument that enables review of a decision by a higher authority to obtain its modification or revocation. In the patent system, appeals are used basically to reverse decisions of patent examiners during the examination procedure as, for example, the decision to reject a patent. Although all patent offices have procedures for appeal against first-instance decisions taken by these offices, there are significant differences as to how this procedure is conducted in each office. This chapter will study the laws and regulations, rules and procedures on appeals in two of the main patent offices in the world – the European Patent Office – EPO and the United States Patent and Trademark Office – USPTO, and in the Brazilian Patent Office – INPI, pointing out the main differences between them.


2019 ◽  
Author(s):  
khoiriazulhijah

AbstractPerbedaan sistem hukum perlindungan lingkup paten di berbagai Negara,tidak hanya mengimpor investasi baru namun juga menentukan proses transfer teknologi suatu Negara. Perlindungan yang meluas menyebabkan transfer teknologi tidak mudah walaupun kurangnya perlindungan karena pemilik paten mengalami kerugian.kedua perbedaan niat tersebut menghasilkan perlunya studi komperatif tentang cangkupan perlindungan paten di Negara-negara. Ada dua masalah yang harus dijajaki, pertama apa perbedaan dan kesamaan cakupan perlindungan paten dalam peraturan negara dan yang kedua bagaimana sistem hukum mempengaruhi kejadian yang berbeda? A.INTRODUCTIONPerkembangan Teknologi suatu Negara,tidak lepas dari aspek perlindungan hak paten yang berlaku pada Negara tersebut. Negara jepang sebagai contoh, adalah Negara yang dikenal paling maju teknologinya.Semula Negara ini banyak mencontoh teknologi Negara-negara Eropa dan Amerika, namun dalam perkembangan yang kita ketahui akhir-akhir ini justru jepanglah yang menjadi kiblat dari Negara-negara lain termasuk Eropa dan Amerika.B.CONTENT1.Perlindungan paten di Negara-Negara Eropa Konvensi Paten Eropa, Undang-Undang Paten Jerman, Amerika Serikat, dan Jepang, dalam makalah “Comparative Study on the Japanese, the United States and the European Patent Systems”, oleh Japan Patent Office Asia-Pacific Industrial Property Center di Jepang belum lama ini (tahun 2001), bila ditelaah banyak mengungkap persamaan/perbedaan perlindungan paten negara-negara tersebut. Beberapa pasal konvensi dan undang-undang negara dimaksud, memperkaya isi tulisan ini.C.CONCLUSIONPerlindungan paten baik bagi negara-negara Eropa yang mengikuti Konvensi Paten Eropa, Jepang maupun Indonesia memiliki persamaan dalam memberikan perlindungan paten berdasarkan prinsip first-to-file, yang berbeda dengan Amerika Serikat berdasarkan prinsip first-to-invent. Sekalipun Amerika Serikat menggunakan prinsip first-to-invent, tetapi Amerika Serikat juga mengatur syarat perlindungan sebagaimana negara-negara Eropa, Jepang dan Indonesia yang berupa penemuan baru, mengandung langkah inventif, dan dapat diterapkan dalam industri. D.DISCUSSIONIndonesia yang sekarang ini dalam undang-undangnya masih mengatur secara umum lingkup perlindungan hak paten, disarankan mengikuti prilaku hakim pengadilan Jepang yang mengadopsi doktrin file wrapper estoppel dan equivalent sebagaimana berlaku di Amerika Serikat. Hal ini didasarkan pertimbangan bahwa doktrin yang dimaksud memberikan keseimbangan pada perlindungan pemegang paten, di samping perlindungan kepentingan negara dalam proses alih teknologi.


2017 ◽  
Vol 17 (3) ◽  
pp. 137-151 ◽  
Author(s):  
Letícia Nonnenmacher ◽  
Marcelo Fabiano Costella ◽  
Monike de Medeiros Costella ◽  
Tarcisio Abreu Saurin

Abstract This article presents a selection method of existing innovations in patents that propose improvements in Temporary Edge Protection Systems (TEPS). The method was divided into three stages. In stage 1, records were collected related to TEPS from the patent filing databases of the Instituto Nacional da Propriedade Industrial (National Institute of Industrial Property, Brazil), the United States Patent and Trademark Office and the European Patent Office. In stage 2, patents were selected based on the TEPS evaluation protocol created by Peñaloza, Formoso and Saurin (2017), which examines safety, efficiency and flexibility criteria. In stage 3, four patents were selected among the 20 patents found related to guard rails and three related to protection nets. Based on the results, one invention stands out that uses hollow posts in protection barriers, which allows for modular movement with safety and flexibility. The framework proposed in this research is a useful resource for disseminating techniques included in TEPS patent databases.


2020 ◽  
Vol 06 ◽  
Author(s):  
Maria Francilene Souza Silva ◽  
Fátima de Cássia E. de Oliveira ◽  
Maria Claudia dos Santos Luciano ◽  
Guilherme J. Zocolo ◽  
Claudia Pessoa

: The genus Phyllanthus belongs to the family Phyllanthaceae with large global distribution, with about 833 species, including Phyllanthus amarus and P. niruri. These species are widely used in traditional medicine because of their pharmacological potential. The objective of this work is to measure the potential of genus Phyllanthus after a technological and scientific monitoring to quantify and evaluate publications and patents related to Phyllanthus spp. with emphasis on P. amarus and P. niruri. The scientific monitoring summarizes morphotaxonomic, pharmacological, chemical, ethnomedicinal and biological aspects. The research was carried out based on papers found in journals deposited in the Web of Science and NCBI (PUBMED) databases and on patents found in the European Patent Office (ESPACENET), Google Patents and the National Institute of Industrial Property (INPI). The results show strong interest in the areas of Pharmacology and Medicinal Chemistry. Patents fall within the Human Necessities section by International Patent Classification as preparations for Medical, Dental or Hygienic Purposes. The summary of monitoring analysis demonstrates the potential pharmacological potential of P. amarus and P. niruri as agents to treat different types of diseases and a range of possibilities for clinical trials in several areas of health.


Author(s):  
V. I. Evdokimov

Relevance. When working in hazardous conditions, eliminating accidents, fires and emergencies, personal respiratory protective equipment (RPE) helps optimize working capacity and preserve the health of workers and the population. The use of RPE is especially important in epidemics spreading by airborne droplets, i.e. in the pandemic of the coronavirus infection SARS-CoV-2. Intention. To analyze the development of patenting and types of inventions in the field of RPE in the world over 20 years from 2000 to 2019.Methodology. The object of the research was patents for inventions, in which headings included the types of respirators and gas masks according to the International Patent Classification (IPC). It should be noted that this classification is somewhat different from that adopted in Russia. Clarivate Analytics’ Derwent Innovations patent database was searched.Results and Discussion. The created search mode made it possible to find 5006 responses to patents for inventions, in which IPC headings were presented by types of respirators and gas masks. Annually, (250 ± 11) inventions with IPC headings by RPE type were paternted worldwide. The dynamics of patenting inventions resembles an inverted U-curve with maximum rates in 2014–2015 and some decrease in the last observation period. The largest contribution to the total array of inventions by RPE type was made by patent families affiliated with the United States (43.9 %), South Korea (22 %), Japan (21.2 %), China (19 %) and the European Patent Office (18.7 %). The structure of the analyzed inventions in the world included RPEs with compressed oxygen or air (7.5 %), with breathing-controlled valves dosing the supply of oxygen or air (4.4 %), with liquid oxygen (0.9 %), with oxygen-releasing chemicals (11.3 %), with filtering elements (20.6 %), hose (2.4 %), for high-altitude aircrafts (4.8%). RPE masks and RPE helmets accounted for 44.1 % and 4 %, respectively. There were regional differences in the patenting of inventions by RPE types.Conclusion. There were quite many domestic inventions on RPE with oxygen-releasing chemicals and with filter elements; the overall contribution of patented inventions in Russia for all RPE types was 6% of the total array.


Author(s):  
Carla Crislan De Souza Bery

The Spondias tuberosa arruda is a fairly integrated type and known in the Brazilian semiarid, being present in the food of the population that lives there. About 18 fruits are in the genus Spondias, and it is known that some of them, like umbu, have antioxidant potential and applicability in several areas. In order to evaluate this potential, it is important a detailed study of all possible applications. This study analyzed the survey results for the bioactive compounds (phenolic compounds and antioxidants) present in umbu pulp (Spondias tuberosa arruda) through patent applications. To perform the patent search was used the bases of the World Intellectual Property Organization (WIPO), the database of the brazilian National Institute of Industrial Property (INPI) and the European Patent Office (Espacenet). This prospect has contributed to the knowledge of researches already developed, especially in order to identify the work in the area of use, characterization, possible applications and potential umbu, focusing on the identification of bioactive compounds and how promising and necessary is a research in that area.


2007 ◽  
Vol 21 (2) ◽  
pp. 169-174
Author(s):  
Mark B. Wilson ◽  
Daniel Alge

Many jurisdictions, including the European Patent Office (EPO), have opposition proceedings in which an interested third party can challenge the validity of the claims of an issued patent. The United States Congress is considering legislation that would introduce opposition proceedings in the USA. This paper reviews the existing EPO and proposed US opposition procedures and provides practical suggestions for dealing with oppositions.


Author(s):  
Melissa M. Hidalgo

Morrissey is a singer and songwriter from Manchester, England. He rose to prominence as a popular-music icon as the lead singer for the Manchester band The Smiths (1982–1987). After the breakup of The Smiths, Morrissey launched his solo career in 1988. In his fourth decade as a popular singer, Morrissey continues to tour the world and sell out shows in venues throughout Europe and the United Kingdom, Asia and Australia, and across North and South America. Although Morrissey enjoys a fiercely loyal global fan base and inspires fans all over the world, his largest and most creatively expressive fans, arguably, are Latinas/os in the United States and Latin America. He is especially popular in Mexico and with Chicanas/os from Los Angeles, California, to San Antonio, Texas. How does a white singer and pop icon from England become an important cultural figure for Latinas/os? This entry provides an overview of Morrissey’s musical and cultural importance to fans in the United States–Mexico borderlands. It introduces Morrissey, examines the rise of Latina/o Morrissey and Smiths fandom starting in the 1980s and 1990s, and offers a survey of the fan-produced literature and other cultural production that pay tribute to the indie-music star. The body of fiction, films, plays, poetry, and fans’ cultural production at the center of this entry collectively represent of Morrissey’s significance as a dynamic and iconic cultural figure for Latinas/os.


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