Severe pre-eclampsia: it’s recognition and management

2016 ◽  
Vol 1 (4) ◽  
Author(s):  
Barry NJ Walters ◽  
Theresa Mittermeier
Keyword(s):  
Clinical Manifestations ◽  
Close Monitoring ◽  
Life Threatening Illness ◽  
Life Threatening

<p>This article deals with certain aspects of the disorder that have not been as well covered in the literature as other elements. The clinical manifestations are manifold, variable and sometimes, if unrecognised, can have unfortunate results. The first truism to accept is that there is no such entity as ‘mild’ pre-eclampsia. All cases have the potential to undergo a transition to a life-threatening illness for mother and baby and, therefore, close monitoring as an inpatient is essential. </p>

scholarly journals Oxford-AstraZeneca Coronavirus Disease-2019 Vaccine-Induced Immune Thrombocytopenia on Day Two

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Azhar Kareem Razzaq ◽  
Ameer Al-Jasim
Keyword(s):  
Platelet Count ◽  
Immune Modulation ◽  
Clinical Manifestations ◽  
Resistance Pattern ◽  
Severe Thrombocytopenia ◽  
Close Monitoring ◽  
Severe Haemorrhage ◽  
Life Threatening ◽  
History Of ◽  
Complete Blood Counts

Introduction. Vaccines have been one of the most impactful human discoveries that have significantly changed life expectancy. Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterized by platelet damage, life-threatening thrombocytopenia, and haemorrhage when the platelet count reaches below 20 × 109/mcL. Its pathogenesis involves viral mimicry or T-cell-induced immune destruction in antibody-negative cases. The clinical manifestations of thrombocytopenia vary according to the severity (level of platelets) and range from being asymptomatic to severe haemorrhage. ITP is treated with immunosuppression. Case Presentation. A 26-year-old Iraqi male laboratory analyst with an unremarkable medical history presented with severe thrombocytopenia 2 days after receiving the Oxford-AstraZeneca coronavirus disease-2019 vaccine. The patient was asymptomatic with unremarkable examination findings. However, his low platelet count was discovered accidentally, and the patient did not exhibit the resistance pattern of ITP and recovered successfully with regular immunosuppressant treatment. Conclusion. Patients with a history of thrombocytopenia can develop vaccine-induced thrombocytopenia earlier than the expected onset. Close monitoring, through regular complete blood counts, is highly recommended for patients with previous thrombocytopenia because the immune modulation process of the vaccine can worsen preexisting thrombocytopenia.

scholarly journals Acute encephalitis as initial presentation of leptospirosis

2017 ◽  
Vol 11 (04) ◽  
pp. 361-363 ◽  
Author(s):  
Edmond Puca ◽  
Joana Majko ◽  
Entela Puca ◽  
Elda Qyra ◽  
Arjet Gega ◽  
...  
Keyword(s):  
Acute Inflammation ◽  
Viral Infections ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Initial Presentation ◽  
Viral Pathogens ◽  
Acute Encephalitis ◽  
Life Threatening Illness ◽  
Life Threatening ◽  
The Brain

Encephalitis is an acute inflammation of the brain matter, very often associated with viral infections, but it can also be caused by non-viral pathogens such as leptospirosis. Leptospirosis is a systemic disease caused by bacteria of the Leptospira genus. Leptospiral infection has a broad spectrum of clinical manifestations ranging from subclinical or mild illness to a fulminant life-threatening illness. In this case report we describe a young patient from Southern Albania with isolated encephalitis caused by Leptospira, where acute encephalitis was the initial presentation of the disease.

Review of Adapting to Life-Threatening Illness.

1987 ◽  
Vol 32 (10) ◽  
pp. 906-906
Author(s):  
No authorship indicated
Keyword(s):  
Life Threatening Illness ◽  
Life Threatening

Life-threatening Illness as Precursor to Posttraumatic Growth

2013 ◽  
Author(s):  
Lawrence G. Calhoun ◽  
◽  
Jay Azarow ◽  
Tzipi Weiss ◽  
Joel Millam
Keyword(s):  
Posttraumatic Growth ◽  
Life Threatening Illness ◽  
Life Threatening

Sophistry and Circumstance at the End of Life

2008 ◽  
Vol 5 (1) ◽  
pp. 81-88
Author(s):  
Philip Berry
Keyword(s):  
Liver Failure ◽  
Medical Personnel ◽  
Medical Decision ◽  
Loss Of Consciousness ◽  
Supportive Treatment ◽  
Medical Decisions ◽  
Life Threatening Illness ◽  
Two Factors ◽  
Life Threatening ◽  
Counselling Process

When life-threatening illness robs a patient of the ability to express their desires, medical personnel must work through the issues of management and prognosis with relatives. Management decisions are guided by medical judgement and the relatives’ account of the patient’s wishes, but difficulties occur when distance grows between these two factors. In these circumstances the counselling process may turn into a doctor-led justification of the medical decision. This article presents two strands of dialogue, in which a doctor, counselling for and against continuation of supportive treatment in two patients with liver failure, demonstrates selectivity and inconsistency in constructing an argument. The specific issues of loss of consciousness (with obscuration of personal identity), statistical ‘futility’ and removal of autonomy are explored and used to bolster diametrically opposed medical decisions. By examining the doctor’s ability to interpret these issues according to circumstance, the author demonstrates how it is possible to shade medical facts depending on the desired outcome.

scholarly journals More comprehensively measuring quality of life in life-threatening illness: the McGill Quality of Life Questionnaire – Expanded

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
S. Robin Cohen ◽  
Lara B. Russell ◽  
Anne Leis ◽  
Javad Shahidi ◽  
Pat Porterfield ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Second Order ◽  
Model Fit ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Healthcare Environment ◽  
Life Threatening Illness ◽  
Life Threatening ◽  
Order Factor

Abstract Background Domains other than those commonly measured (physical, psychological, social, and sometimes existential/spiritual) are important to the quality of life of people with life-threatening illness. The McGill Quality of Life Questionnaire (MQOL) – Revised measures the four common domains. The aim of this study was to create a psychometrically sound instrument, MQOL – Expanded, to comprehensively measure quality of life by adding to MQOL-Revised the domains of cognition, healthcare, environment, (feeling like a) burden, and possibly, finance. Methods Confirmatory factor analyses were conducted on three datasets to ascertain whether seven new items belonged with existing MQOL-Revised domains, whether good model fit was obtained with their addition as five separate domains to MQOL-Revised, and whether a second-order factor representing overall quality of life was present. People with life-threatening illnesses (mainly cancer) or aged > 80 were recruited from 15 healthcare sites in seven Canadian provinces. Settings included: palliative home care and inpatient units; acute care units; oncology outpatient clinics. Results Good model fit was obtained when adding each of the five domains separately to MQOL-Revised and for the nine correlated domains. Fit was acceptable for a second-order factor model. The financial domain was removed because of low importance. The resulting MQOL-Expanded is a 21-item instrument with eight domains (fit of eight correlated domains: Comparative Fit Index = .96; Root Mean Square Error of Approximation = .033). Conclusions MQOL-Expanded builds on MQOL-Revised to more comprehensively measure the quality of life of people with life-threatening illness. Our analyses provide validity evidence for the MQOL-Expanded domain and summary scores; the need for further validation research is discussed. Use of MQOL-Expanded will enable a more holistic understanding of the quality of life of people with a life-threatening illness and the impact of treatments and interventions upon it. It will allow for a better understanding of less commonly assessed but important life domains (cognition, healthcare, environment, feeling like a burden) and their relationship to the more commonly assessed domains (physical, psychological, social, existential/spiritual).

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