scholarly journals Small But Powerful Optically: Glass Microcapillaries for Studying Complex Fluids or Biological Systems with Submicrolitre Samples under Harsh Conditions

2020 ◽  
Vol 19 (3) ◽  
pp. 221-227
Author(s):  
Kedi Zhou ◽  
Patrick Bouriat ◽  
Nelly Hobeika ◽  
Abdelhafid Touil ◽  
Anthony Ranchou-Peyruse ◽  
...  
1991 ◽  
Vol 248 ◽  
Author(s):  
Reinhard Lipowsky ◽  
Joanna Cook-RÖder

AbstractMembranes such as lipid bilayers are highly flexible surfaces which determine the architecture of biological systems and provide a basic structural element for the mesophases of complex fluids1. Two aspects of their conformational behavior will be considered. First, the morphology of vesicles and membranes is briefly reviewed. Then, recent theoretical work on adhesion (or cohesion) phenomena which involve whole bunches of membranes will be discussed.


Author(s):  
Yidi Li ◽  
Hang Ping ◽  
Zhaoyong Zou ◽  
Jing-Jing Xie ◽  
Weiming Wang ◽  
...  

The formation of natural structures found in biological systems is wonderful and fabricates biomaterials at ambient temperatures, in contrast to our artificial technologies wherein harsh conditions are common prerequisites. A...


Author(s):  
Henry S. Slayter

Electron microscopic methods have been applied increasingly during the past fifteen years, to problems in structural molecular biology. Used in conjunction with physical chemical methods and/or Fourier methods of analysis, they constitute powerful tools for determining sizes, shapes and modes of aggregation of biopolymers with molecular weights greater than 50, 000. However, the application of the e.m. to the determination of very fine structure approaching the limit of instrumental resolving power in biological systems has not been productive, due to various difficulties such as the destructive effects of dehydration, damage to the specimen by the electron beam, and lack of adequate and specific contrast. One of the most satisfactory methods for contrasting individual macromolecules involves the deposition of heavy metal vapor upon the specimen. We have investigated this process, and present here what we believe to be the more important considerations for optimizing it. Results of the application of these methods to several biological systems including muscle proteins, fibrinogen, ribosomes and chromatin will be discussed.


Sign in / Sign up

Export Citation Format

Share Document