scholarly journals Multi-tool approach for high risk aspirin desensitization in a pregnant woman

Author(s):  
E Pérez Rodríguez ◽  
JA Martínez Tadeo ◽  
G Hernández Santana ◽  
FJ Iglesias Souto ◽  
E Rodríguez Plata ◽  
...  
Phlebologie ◽  
2015 ◽  
Vol 44 (01) ◽  
pp. 7-13
Author(s):  
R Becker ◽  
M Breitkopf ◽  
S Baumgarten ◽  
G Halis ◽  
A Höhne ◽  
...  

SummaryIntroduction: The efficacy of a therapy with certoparin; also in combination with aspirin and prednisolone; in high-risk pregnancies has been examined prospectively.Method: Data of 616 pregnancies have been analyzed. 238 patients injected Mono Embolex 3000; 239 patients Mono Embolex 8000 only. 62 patients injected Mono Embolex 8000 and took aspirin 50–100 mg daily; 60 Mono Embolex 3000 and aspirin 50–100 mg daily. 30 patients took aspirin 50–100 mg; prednisolone 2.5–5 mg and 17 injected mono Embolex 8000; 13 Mono Embolex 3000 daily from the start of their pregnancy. The target variable was the life birth rate.When given aspirin the HPA-status of the partner is measured if the pregnant woman is negative for HPA 1a or 5b. In HPA-negative mothers and HPA-positive fathers a test for HPA-antibodies is performed posterior week 16.Result: Applied early; a mean life birth rate of 95 % has been achieved in the monotherapy with Mono Embolex. Where heparin and aspirin were applied before pregnancy week 17 a life birth rate of 100 % was achieved. In patientswith a combination of aspirin and prednisolone a life birth rate of 87 % was achieved. Considering the life birth rate the status of thrombophilia gene-polymorphisms is irrelevant. The HPA-status was examined in 139 patients. In one of the HPA 5a-negative and 3 of the HPA 5b-negative women an immunization occurred but the platelet count of the fetus was not decreased. 3.3 % showed local allergic reaction and 0.5 % slight bleeding.Conclusion: Certoparin, aspirin and prednisolone are safe drugs to increase life birth rate.


2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Vidhi Rawat ◽  
Alok Jain ◽  
Vibhakar Shrimali

Ultrasound (US) image segmentation methods, focusing on techniques developed for fetal biometric parameters and nuchal translucency, are briefly reviewed. Ultrasound medical images can easily identify the fetus using segmentation techniques and calculate fetal parameters. It can timely find the fetal abnormality so that necessary action can be taken by the pregnant woman. Firstly, a detailed literature has been offered on fetal biometric parameters and nuchal translucency to highlight the investigation approaches with a degree of validation in diverse clinical domains. Then, a categorization of the bibliographic assessment of recent research effort in the segmentation field of ultrasound 2D fetal images has been presented. The fetal images of high-risk pregnant women have been taken into the routine and continuous monitoring of fetal parameters. These parameters are used for detection of fetal weight, fetal growth, gestational age, and any possible abnormality detection.


2021 ◽  
Vol 20 (2) ◽  
pp. 453-455
Author(s):  
Lau Yee Theng ◽  
Razlina Abdul Rahman ◽  
Iu Kwang Kwok ◽  
Shaiful Bahari Ismail

Ocular sporotrichosis is a relatively rare infection. We report a case of right ocular sporotrichosis in a 35 year-old pregnant woman at 30-week period of gestation with underlying retroviral disease on highly active antiretroviral therapy (HAART). She presented with one month history of unilateral eye redness and itchiness. Her symptoms persisted despite treatment for conjunctivitis. She was subsequently referred to ophthalmology clinic and a diagnosis of ocular sporotrichosis was made based on the culture of excised conjunctival tissues. Her symptoms improved after she was treated with fluconazole eye drops and intralesional amphotericin B. This case highlights the importance of early referral to ophthalmology in the case of unilateral eye redness in a high risk patient with history of exposure to infected cat prior to presentation. Bangladesh Journal of Medical Science Vol.20(2) 2021 p.453-455


1997 ◽  
Vol 26 (4) ◽  
pp. 423-430 ◽  
Author(s):  
Annette Gupton ◽  
Maureen Heaman ◽  
Terri Ashcroft
Keyword(s):  

2015 ◽  
Vol 23 (2) ◽  
pp. 157-166 ◽  
Author(s):  
Karthik Sivashanker ◽  
Michael Mufson ◽  
Leena Mittal ◽  
Edgar Ross ◽  
Joji Suzuki

2014 ◽  
Vol 155 (29) ◽  
pp. 1147-1151
Author(s):  
Petronella Hupuczi ◽  
János Gál

Recently the most frequently applied surgical procedure worldwide has been Cesarean section. It is essential to perform the operation without any complication. In addition, a fast postoperative recovery must be provided, because all mothers must have the chance for being together with their newborn infant even on the first day. The maternal mortality rates of Cesarean section significantly decreased in the last decades due to the planned team work as well as the widely applied regional (spinal and epidural) anesthetic procedures. Apart from the obstetrician and neonatologist the anesthesiologist is the member of the perinatal team, too, who is responsible for the patient’s perioperative care. To prevent complications and have an early successful treatment the anesthesiologist should be informed by the pregnant woman’ s health status in time in order to be able to plan the perioperative management. The high-risk groups of pregnant women, the most common causes of maternal death and possibilities of prevention and treatment are discussed. Orv. Hetil., 2014, 155(29), 1147–1151.


2021 ◽  
pp. 46-48
Author(s):  
Yunus Emre TOPDAĞI

Spontaneous pregnancy in women with Turner syndrome is rare (5%) and relative- ly high risk. A number of methods to preserve fertility in such women have been discussed. Careful follow-up is required during these pregnancies due to the high incidence rates of neonatal, obstetric, maternal, and cardiovascular complications. A 39-year-old multigravid woman (G5, P3, A2) with mosaic Turner syndrome with a history of three spontaneous pregnancies and two miscarriages was evaluated at our clinic. The analysis showed mos 45,X [9]/46,XX [38] mosaic Turner syndrome. Her first and fourth pregnancies resulted in miscarriages during the first trimester. Here, we discuss a pregnant woman with mosaic Turner syndrome with unaffected fertility but with a history of spontaneous pregnancies/miscarriages, with reference to the current literature.


Author(s):  
Troy Fonda ◽  
Hermina Novida

Gestational diabetes mellitus (GDM) is a hyperglycemic condition that is first discovered during pregnancy. GDM is a high-risk condition during pregnancy, for both mother and fetus. GDM affects about 1–14% of pregnancies. In the last 20 years, the incidence of gestational diabetes has been increasing. High iron load and disorders of iron metabolism have been associated with glucose metabolism. The beta thalassemias are a group of hereditary hemoglobinopathies. Treatment for beta thalassemias patients is transfusion, but intensive transfusion can aggravate iron overload in patients. In this study, a case of GDM in a pregnant woman with beta-thalassemia was reported.


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