scholarly journals Impact of an at home exercise program in the pediatric, adolescent, and young adult cancer population newly diagnosed with acute lymphoblastic leukemia

2020 ◽  
Vol 3 ◽  
Author(s):  
Punit Vyas ◽  
Danielle Halsey ◽  
Nicholas Kelly ◽  
Melissa Sherman ◽  
Brooklyn Herbert ◽  
...  
Keyword(s):  
Physical Activity ◽  
Exercise Intervention ◽  
Lymphoblastic Leukemia ◽  
Exercise Program ◽  
Adult Survivors ◽  
Home Exercise ◽  
Control Group ◽  
Newly Diagnosed ◽  
At Home

Background: Over 30,000 cases of leukemia are diagnosed each year in the United States. For individuals ages 0-39, the one-year relative survival rate is 84.5%, and the 5-year survival is 94%. Improved survival rates come with long-term health challenges due to treatment, including cardiovascular disease, obesity, diabetes, fatigue,  low quality of life (QOL), and reduced physical activity (PA). Current literature shows structured exercise in adult survivors can be beneficial for improving the long-term health effects resulting from treatment. Exercise induces the release of many growth factors into the bloodstream that aid in repair of the body following insult. Three factors specific to nerve damage is brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and Platelet-derived growth factor (PDGF). The benefits of exercise seen in adult survivors may translate to young survivors. We hypothesized that an 8-week at home exercise program in newly diagnosed acute lymphoblastic leukemia (ALL) patients (ages 5-25) would improve outcomes compared to baseline or a control group. The preliminary findings presented are based on the initial ten subjects and include physical, biomarker and self-reported outcomes.  Experimental Methods: Newly diagnosed ALL patients were assigned to an 8-week at home exercise intervention during the consolidation phase of treatment. Fitbit activity tracker data and questionnaires were used for assessing adherence and feasibility. Blood samples were taken at baseline and at week eight.  Results:  Subjects were not able to complete over 75% of the exercise intervention; however, they did increase their overall physical activity and their neuropathy scores decreased compared to baseline. BDNF significantly increased in the control group, but not in the exercise group.  Conclusion: The results indicate that an exercise program in this population during the consolidation phase may not be feasible. It also supports the association between neuropathy, physical activity, and BDNF levels after long term exercise. 

scholarly journals Role and effectiveness of complex and supervised rehabilitation on overall and hand function in systemic sclerosis patients—one-year follow-up study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Michał Waszczykowski ◽  
Bożena Dziankowska-Bartkowiak ◽  
Michał Podgórski ◽  
Jarosław Fabiś ◽  
Arleta Waszczykowska
Keyword(s):  
Systemic Sclerosis ◽  
Hand Function ◽  
Exercise Program ◽  
Rehabilitation Program ◽  
Long Term Results ◽  
Home Exercise ◽  
Control Group ◽  
Study Group

AbstractThe aim of this study was to estimate the long-term results of complex and supervised rehabilitation of the hands in systemic sclerosis (SSc) patients. Fifty-one patients were enrolled in this study: 27 patients (study group) were treated with a 4-week complex, supervised rehabilitation protocol. The control group of 24 patients was prescribed a home exercise program alone. Both groups were evaluated at baseline and after 1-, 3-, 6-, and 12-months of follow-up with the Disability of the Arm, Shoulder and Hand Questionnaire (DAHS) as the primary outcome, pain (VAS—visual analog scale), Cochin Hand Function Scale (CHFS), Health Assessment Questionnaire Disability Index (HAQ-DI), Scleroderma-HAQ (SHAQ), range of motion (d-FTP—delta finger to palm, Kapandji finger opposition test) and hand grip and pinch as the secondary outcomes. Only the study group showed significant improvements in the DASH, VAS, CHFS and SHAQ after 1, 3 and 6 months of follow-up (P = 0.0001). Additionally, moderate correlations between the DASH, CHFS and SHAQ (R = 0.7203; R = 0.6788; P = 0.0001) were found. Complex, supervised rehabilitation improves hand and overall function in SSc patients up to 6 months after the treatment but not in the long term. The regular repetition of this rehabilitation program should be recommended every 3–6 months to maintain better hand and overall function.

scholarly journals Delivering an In-Home Exercise Program via Telerehabilitation: A Pilot Study of Lung Transplant Go (LTGO)

2016 ◽  
Vol 8 (2) ◽  
pp. 15-26 ◽  
Author(s):  
JiYeon Choi ◽  
Andrea L. Hergenroeder ◽  
Lora Burke ◽  
Annette DeVito Dabbs ◽  
Matthew Morrell ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Function ◽  
Lung Transplant ◽  
Exercise Intervention ◽  
Exercise Program ◽  
Integrated System ◽  
Home Exercise ◽  
Transplant Recipients ◽  
Walk Distance ◽  
Lung Transplant Recipients

We evaluated the feasibility, safety, system usability, and intervention acceptability of Lung Transplant Go (LTGO), an 8-week in-home exercise intervention for lung transplant recipients using a telerehabilitation platform, and described changes in physical function and physical activity from baseline to post-intervention. The intervention was delivered to lung transplant recipients in their home via the Versatile and Integrated System for TeleRehabilitation (VISYTER). The intervention focused on aerobic and strengthening exercises tailored to baseline physical function. Participants improved walk distance (6-minute walk distance), balance (Berg Balance Scale), lower body strength (30-second chair stand test) and steps walked (SenseWear Armband®). No adverse events were reported. Participants rated the program highly positively in regard to the technology and intervention. The telerehabilitation exercise program was feasible, safe, and acceptable. Our findings provide preliminary support for the LTGO intervention to improve physical function and promote physical activity in lung transplant recipients. 

Serum Myostatin Levels Are Higher in Fitter, More Active, and Non-Frail Long-Term Nursing Home Residents and Increase after a Physical Exercise Intervention

Gerontology ◽  
2018 ◽  
Vol 65 (3) ◽  
pp. 229-239 ◽  
Author(s):  
Haritz Arrieta ◽  
Gotzone Hervás ◽  
Chloe Rezola-Pardo ◽  
Fátima Ruiz-Litago ◽  
Miren Iturburu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Nursing Home ◽  
Physical Fitness ◽  
Physical Activity Level ◽  
Exercise Intervention ◽  
Nursing Home Residents ◽  
Exercise Program ◽  
Activity Level

Background: Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. Objective: To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and frailty in long-term nursing home residents. We also aimed to ascertain the effect of an exercise program on myostatin levels. Methods: We obtained study data on 112 participants from long-term nursing homes. Participants were randomly assigned to a control or an intervention group and performed a 6-month multicomponent exercise program. Serum myostatin levels were analyzed by ELISA. Assessments also included body composition (anthropometry and bioelectrical impedance), physical fitness (Senior Fitness Test), physical activity level (accelerometry), and frailty (Fried frailty criteria, Clinical Frailty Scale, and Tilburg frailty indicator). Results: The concentration of myostatin at baseline was positively correlated with: a leaner body composition (p < 0.05), and a higher number of steps per day and light and moderate-vigorous physical activity in women (p < 0.005); greater upper and lower limb strength, endurance, and poorer flexibility (p < 0.05) in men; and better performance (less time) in the 8-ft timed up-and-go test in both women (p < 0.01) and men (p < 0.005). We observed higher concentrations of serum myostatin in non-frail than in frail participants (p < 0.05). Additionally, we found that the implemented physical exercise intervention, which was effective to improve physical fitness, increased myostatin concentration in men (p < 0.05) but not in women. The improvements in physical condition were related with increases in serum myostatin only in men (p < 0.05–0.01). Conclusions: Higher serum levels of myostatin were found to be associated with better physical fitness. The improvements in physical fitness after the intervention were positively related to increases in myostatin concentrations in men. These results seem to rule out the idea that high serum myostatin levels are indicative of frailty in long-term nursing home residents. However, although the direction of association was opposite to that expected for the function of myostatin, the use of this protein as a biomarker for physical fitness, rather than frailty, merits further study.

Physical Activity Across the Cancer Journey: Experiences and Recommendations From People Living With and Beyond Cancer

2019 ◽  
Vol 100 (3) ◽  
pp. 575-585
Author(s):  
Mairéad Cantwell ◽  
Deirdre Walsh ◽  
Bróna Furlong ◽  
Lisa Loughney ◽  
Noel McCaffrey ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sense Of Self ◽  
Exercise Program ◽  
Well Being ◽  
Home Exercise ◽  
Program Success ◽  
Rehabilitation Programs ◽  
Cancer Support ◽  
And Control

Abstract Background The majority of individuals living with and beyond cancer are not sufficiently active to achieve health benefits. Objective The aim of this study was to explore individuals’ experiences of physical activity (PA) behavior across the cancer journey and to ask individuals living with and beyond cancer to identify strategies to support habitual PA. Design An exploratory, descriptive, qualitative design was used. Methods Purposive sampling methods were used to recruit individuals living with and beyond cancer who had been referred to, and/or participated in, a community-based exercise program or were attending a cancer support center. The focus group discussions were audio recorded, transcribed verbatim, and analyzed using a thematic analysis approach. Results Seven focus groups were conducted with 41 participants. Many individuals reported that regular PA provided a vehicle for recovery that created a sense of “self-power,” defined as taking ownership and control of one’s health to increase well-being. Barriers to PA participation included environmental-, patient-, and treatment-related challenges. Recommendations to support long-term adherence to PA included completion of fitness assessments at regular intervals and provision of a home exercise program. Limitations The benefits and barriers to PA participation for individuals diagnosed with cancers that were not represented may not have been identified. The strategies recommended to support habitual PA may be salient only to individuals whose cancer diagnoses were represented. Conclusions Exercise is seen as a vehicle for recovery from cancer but long-term adherence for individuals is complex. The findings from this study can inform the development of exercise oncology rehabilitation programs and could support a greater likelihood of program success, thereby optimizing the health, well-being, and quality of life of survivors of cancer.

scholarly journals Response to Long Term Exercise Training in COPD

2021 ◽  
Vol 10 (11) ◽  
pp. 849-851
Author(s):  
Renukadevi Mahadevan ◽  
Chaya Sindaghatta ◽  
Vijay Samuel Raj Victor
Keyword(s):  
Exercise Training ◽  
Perceived Exertion ◽  
Exercise Intervention ◽  
Exercise Program ◽  
Home Exercise ◽  
Chronic Obstructive ◽  
Peripheral Oxygen Saturation ◽  
Obstructive Pulmonary Disease ◽  
Long Acting

The patient is a 64-year-old male. He presented with difficulty in breathing and was diagnosed with COPD (chronic obstructive pulmonary disease) ten years back. He is a farmer and an active smoker, of 18 packs / year for 35 years. He began to experience dyspnoea when performing moderate exertion, dyspnoea grading of 3 as denoted by modified medical research council mMRC (Modified Medical Research Council) and productive cough with sputum, usually in the morning. He is on long-term oxygen therapy of 4 litres of oxygen for 16 hours per day for 2 years. He has a history of hospitalisation six times and 5 - 6 emergency consultations for acute exacerbation in the last 3 years. The patient was on regular treatment with long-acting inhaled beta-2 agonist (LABA) inhaler and long-acting anticholinergics or long-acting muscarinic receptor antagonists (LAMA) and corticosteroid (ICS) inhalers 200-400 micrograms (μg) three times a day and mometasone 400 μg, continuously. The patient’s body mass index (BMI) was 20.3 Kg / m2. His blood pressure was 140 / 80 mmHg, heart rate (HR) 74 bpm, respiratory rate (RR) 22 rpm and peripheral oxygen saturation (SpO2) at rest was 95 %. Pulmonary auscultation revealed a diffusely reduced breath sounds, and no alterations were found in cardiac auscultation. The patient’s post-bronchodilator pulmonary function test was 52.2 % of forced expiratory volume in 1 second (FEV1). In the six-minute walk test(6mwt), the patient walked a total distance of 294.4 meters, with variations in heart rate from 74bpm to 128bpm. Whenever peripheral oxygen saturation was reduced to 88 %, the patient had taken rest. The patient took rest two times, at the end of the second minute thirtyfive seconds and the end of the fourth minute forty-five seconds. The body-mass index, airflow obstruction, dyspnoea and exercise (BODE) mortality index were used to measure 4 years survival interpretation.1 Saint George’s Respiratory Questionnaire chronic obstructive pulmonary disease (COPD) version (SGRQ-C) was used to measure the quality of life (QoL). After the initial assessment, the patient was enrolled in the pulmonary rehabilitation program. The first three months were supervised, exercise training constituted weekly educational sessions and meeting with the psychology support group and nutrition advice before beginning the exercise intervention. 2 The patient visited the institution three days per week for exercise training. The exercise constituted aerobic on the treadmill and intensity, in the beginning, was 80 % of the 6MWT speed, and Borg’s scale of perceived exertion was 4 as prescribed by American Thoracic Society (ATS). 3 The components of the program were warm-up sessions, conditioning, resistance exercise and a cool-down session. The patient was also advised home exercise program, which included resistance training using weighted sandbags for three sessions per week. The resistance added was based on 1 repetition maximum (RM) and 10RM. 80 % of 10 RM was the training intensity for resistance training for a larger group of muscles. 4 The weight was added gradually and ensured their rated perceived exertion (RPE) was at 4 during exercise. The patient’s outcomes were recorded after three months of training. After 12 weeks of supervised outpatient exercise intervention, the patient was advised home exercise program for the next 6 months. 5

Home Based Exercise Intervention in Pregnant Indian Women: Effects on Weight and Obesity Markers

2018 ◽  
Vol 25 (2) ◽  
pp. 131-139
Author(s):  
Alka Pawalia ◽  
Sivachidambaram Kulandaivelan ◽  
Satya Savant ◽  
Vikram Singh Yadav
Keyword(s):  
Physical Activity ◽  
Exercise Intervention ◽  
Physical Activity Intervention ◽  
Exercise Group ◽  
Home Exercise ◽  
Control Group ◽  
Weight Retention ◽  
Singleton Pregnancy ◽  
Supervised Exercise ◽  
Home Based

Abstract Background and Aims: The purpose of this study was to investigate the effect of a home based physical activity intervention during pregnancy on weight and various obesity markers resulting in metabolic syndrome in future. Methods: The paper presents a pilot experimental study (pre-post comparison) from a larger ongoing trial, with40 pregnant women (20 each) having singleton pregnancy of >16 weeks of gestation, BMI >18.5 Kg/m2 and declared fit by gynecologist for physical activity during pregnancy. They were assigned to either home exercise group receiving antenatal weight loss intervention delivered via 2 exercise demonstration sessions and informative brochures with advised regular 30 minutes walking during pregnancy, while control group was advised once at initial recruitment for maintaining active lifestyle during pregnancy. The data was analyzed using IBM-SPSS-(version 21) software. Results: Though the exercise group had less weight gain and weight retention than the control group, the pregnancy home intervention alone was not effective in controlling obesity parameters like body mass index (BMI), waist circumference (WC), hip circumference (HC) and waist to hip ratio (W/H).Conclusion: Home based pregnancy exercise intervention should include other adjunct components, which could be diet advice or timely supervised exercise sessions to have appreciable obesity control during pregnancy.

scholarly journals Effect of Motivation by “Instagram” on Adherence to Physical Activity among Female College Students

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Einas Al-Eisa ◽  
Asma Al-Rushud ◽  
Ahmad Alghadir ◽  
Shahnawaz Anwer ◽  
Bashayer Al-Harbi ◽  
...  
Keyword(s):  
Physical Activity ◽  
College Students ◽  
Intervention Group ◽  
Exercise Program ◽  
Female College Students ◽  
Home Exercise ◽  
Control Group ◽  
Home Exercise Program ◽  
Female College ◽  
Activity Program

Objective.To investigate the efficacy of using “Instagram application” with a “home-exercise program” as a motivational stimulus in improving physical activity (PA) adherence levels among female college students.Methods.Fifty-eight female undergraduate students with the mean age20.3±0.96years participated. Participants were divided into two groups: intervention and the control group; both the groups received an exercise program and the intervention group was additionally motivated by “Instagram.” Adherence to PA was measured by using an adherence sheet. The Exercise Motivation Inventory (EMI-2) was used to assess the motivational factors.Results.The most frequent motivational factors were extrinsic as assessed using the EMI-2. “Positive health” was the most frequent factor mentioned of the two types with 47% of the sample. The intervention group adhered with 17% more to the activity program compared to the control group. Moreover, 72% of the participants in the intervention and control groups found the activity program flexible enough to be performed at home; they agreed about its effectiveness on adherence (53%).Conclusions.The use of Instagram with the home exercise program as a motivational modality could be attractive and effective to reinforce adherence and maintain an appropriate PA level.

scholarly journals Effectiveness of a Targeted Exercise Intervention in Reversing Older People's Mild Balance Dysfunction: A Randomized Controlled Trial

2012 ◽  
Vol 92 (1) ◽  
pp. 24-37 ◽  
Author(s):  
Xiao Jing Yang ◽  
Keith Hill ◽  
Kirsten Moore ◽  
Susan Williams ◽  
Leslie Dowson ◽  
...  
Keyword(s):  
Older People ◽  
Exercise Intervention ◽  
Physical Therapist ◽  
Controlled Trial ◽  
Intervention Group ◽  
Exercise Program ◽  
Home Exercise ◽  
Control Group ◽  
Home Exercise Program ◽  
Randomized Controlled

Background Previous research has mainly targeted older people with high risk of falling. The effectiveness of exercise interventions in older people with mild levels of balance dysfunction remains unexplored. Objective This study evaluated the effectiveness of a home balance and strength exercise intervention in older people systematically screened as having mild balance dysfunction. Design This was a community-based, randomized controlled trial with assessors blinded to group allocation. Participants Study participants were older people who reported concerns about their balance but remained community ambulant (n=225). After a comprehensive balance assessment, those classified as having mild balance dysfunction (n=165) were randomized into the trial. Intervention Participants in the intervention group (n=83) received a 6-month physical therapist–prescribed balance and strength home exercise program, based on the Otago Exercise Program and the Visual Health Information Balance and Vestibular Exercise Kit. Participants in the control group (n=82) continued with their usual activities. Outcome Measures Laboratory and clinical measures of balance, mobility, and strength were assessed at baseline and at a 6-month reassessment. Results After 6 months, the intervention group (n=59) significantly improved relative to the control group (n=62) for: the Functional Reach Test (mean difference=2.95 cm, 95% confidence interval [CI]=1.75 to 4.15), the Step Test (2.10 steps/15 seconds, 95% CI=1.17 to 3.02), hip abductor strength (0.02, 95% CI=0.01 to 0.03), and gait step width (2.17 cm, 95% CI=1.23 to 3.11). There were nonsignificant trends for improvement on most other measures. Fourteen participants in the intervention group (23.7%) achieved balance performance within the normative range following the exercise program, compared with 3 participants (4.8%) in the control group. Limitations Loss to follow-up (26.6%) was slightly higher than in some similar studies but was unlikely to have biased the results. Conclusions A physical therapist–prescribed home exercise program targeting balance and strength was effective in improving a number of balance and related outcomes in older people with mild balance impairment.

scholarly journals The Effects of Baduanjin Exercise on BMI, Waist-Hip Ratio and Lipids Among Perimenopausal Women

2020 ◽  
Vol 5 (1) ◽  
pp. 29
Author(s):  
Li-Yun Szu ◽  
Lee-Ing Tsao
Keyword(s):  
Metabolic Syndrome ◽  
Exercise Intervention ◽  
Home Exercise ◽  
Control Group ◽  
Positive Effects ◽  
Waist Hip Ratio ◽  
Perimenopausal Women ◽  
Experimental Group ◽  
At Home

Background: The Prevalence of metabolic syndrome is increasing in perimenopausal women. BMI, waist-hip ratio (WHR) and lipids are important factors for controlling metabolic syndrome. The Baduanjin exercise is a traditional Chinese exercise that promotes the integration of physical and mental health, and it is easy to practice at home and fit for busy perimenopausal women. However, the health effects needed to be evaluated.Aim: The purpose of this quasi-experimental research was to evaluate the effects, after twelve weeks of practicing Baduanjin exercise.Methods: This study was conducted at two Buddhism painting clubs, using a parallel-design, control trial recruiting perimenopausal women. There were three instruments: (1) BMI, (2) Waist-Hip Ratio, (3) Lipids—HDL and LDL. The intervention effects from the study baseline to a twelve weeks follow-up were estimated using T-test to evaluate the effectiveness of Baduanjin exercise. The Baduanjin exercise intervention included one-on-one teaching and telephone follow-up to help women practice Baduanjin exercise of 10-15 minutes twice per day for twelve weeks at home. Result: A total of 54 women aged 40 to 60 were recruited from two Buddhism painting clubs. Twenty-seven women were in the experimental group, while 27 women were in the control group. Positive effects were found after 12 weeks doing Baduanjin exercise of 10-15 minutes twice per day at home. In the experimental group, women improved their health by significantly decreasing BMI, increasing HDL, decreasing LDL and more slowly increasing WHR compared with the control group. Conclusion: Baduanjin exercise is a good home exercise to suggest perimenopausal women to improve their BMI, waist-hip ratio and lipid

Sign in / Sign up

Export Citation Format

Share Document