Hemodynamic monitoring on the background of intensive therapy in newborns

2017 ◽  
Vol 8 (5) ◽  
pp. 74-82 ◽  
Author(s):  
Irina V. Boronina ◽  
Yury S. Aleksandrovich ◽  
Irina N. Popova ◽  
Ludmila S. Oshanova

The article deals with the problem of early neonatal and infant mortality. It is pointed out that recent advances in emergency and intensive care therapy have provided decline in early neonatal and infant mortality. Hemodynamic disorders are reported to be associated with any severe pathology in patients of all age groups including newborns, significantly influence quality of life of patients having experienced a critical condition. Clinical manifestations of hemodynamic disorders in infants are not considered to be specific; they are critically delayed and are not timely recognized. The article describes peculiarities of the cardio-vascular system of newborns that are responsible for the necessity of thorough hemodynamic profile monitoring in order to provide detection of vital function alterations at the early stages, ensure timely onset of intensive therapy and its qualitative performance. Special attention is paid to current methods of determination of central hemodynamic parameters, which are stated to be divided into invasive and non-invasive. The paper also highlights some peculiarities of evaluation of hemodynamic findings using specific monitoring methods and factors influencing the outcome. The article specifies increased interest towards non-invasive monitoring tools of hemodynamic profile in recent years; their relevance is stated to be doubtless in both pediatric and neonatal practice. The main task of any monitoring procedure is reported to be hemodynamic findings analysis, “trend tracking” in the process of monitoring a patient and intensive therapy performance.

2017 ◽  
Vol 90 (1) ◽  
pp. 33-39
Author(s):  
Renata Nicula ◽  
Doru Diculescu ◽  
Codruţa Claudia Lencu ◽  
Răzvan Ciortea ◽  
Carmen Elena Bucuri ◽  
...  

Background and aims. Perimenopause is marked by clinical manifestations which disturb everyday life and which may also hide a pathomorphological, more precisely endometrial, substrate. An accurate early diagnosis established by accessible, non-invasive methods is very important for the therapeutic management.Method. The study included 103 patients aged between 41.5–55.11 years, divided into 3 age groups: 40-44 years (n=10), 45-49 years (n=54) and ≥50 years (n=39).Results. Certain risk factors of endometrial neoplasm or premalignant conditions were evidenced, their accurate identification being useful in limiting the number of patients with abnormal uterine bleeding (AUB) submitted to diagnostic screening. The most common cause of AUB in our study was fibroma, followed by functional causes.Conclusions. Transvaginal ultrasound (TVUS) represents a minimally invasive method for the screening of perimenopausal patients with AUB, especially to rule out endometrial adenocarcinoma (EAC). TVUS sensitivity was higher than clinical diagnosis in case of leiomioma, polypi and EAC. TVUS was more accurate in the diagnosis of EAC, polypi and leiomioma.


2015 ◽  
Vol 22 (3) ◽  
pp. 15-20
Author(s):  
Еськов ◽  
Valeriy Eskov ◽  
Филатова ◽  
O. Filatova ◽  
Еськов ◽  
...  

The identification of parameters of the cardio-vascular system has not only medical but also social and economic aspects. The work affects the age-related aspects of the state of the cardio-vascular system at different age groups of the female population of Ugra. It was demonstrated the increase in aboriginal and migrant populations of sympathetic activity status autonomous nervous system with age, but a separate component - cardiointervals - operates in different ways in these two groups. The volume of the quasi-attractors for the cardiointervals exponentially decreases in Khanty with age. In the immigrant population an increase in the area of quasi-attractors for parabolic type is observed. The increase with age is a poor prognosis for longevity and the age.


2019 ◽  
Vol 12 (2) ◽  
pp. 94-99
Author(s):  
Rene D. Mileva-Popova ◽  
Nina Y. Belova

Summary Vascular-ventricular coupling is a major determinant of left ventricular load. The aim of our study was to assess non- invasively left ventricular load and its dependency on central hemodynamics. Sixty-five healthy and gender-matched individuals were divided in two groups according to their age: 20y/o and 50y/o. Applanation tonometry was performed using the Sphygmocor device. Central pressures and pulse wave analysis indices were computed. Central systolic (120±3 vs. 98±2 mm Hg) and pulse pressures (43±3 vs. 29±1 mm Hg) as well as the augmentation index (AIx75) (23±3 vs. 6±2%) were significantly higher in the 50y/o group (p<0.01). These parameters are relevant markers of arterial stiffness and evidenced the development of central arterial morphological and functional alterations in the older subjects. The time-tension index (TTI) computed from the systolic pressure area was significantly higher in the 50y/o subjects as compared to the 20y/o group (2378±66 vs. 1954±73 mmHg×s, p<0.01). Moreover, we have shown the presence of significant correlation between TTI and AIx75 (p<0.01) in both age groups. This finding confirmed the contribution of arterial stiffness for the impaired vascular-ventricular coupling. In conclusion, applanation tonometry might be utilized for non-invasive evaluation of the left ventricular load, which is an important parameter of cardiovascular risk.


2017 ◽  
Vol 2 (2) ◽  
pp. 66-70
Author(s):  
N. A. Vaschuk ◽  
◽  
M. U. Prudenko ◽  
N. S. Hloba ◽  
A. A. Kurbel

Author(s):  
L. Yu. Orekhova ◽  
A. A. Petrov ◽  
E. S. Loboda ◽  
I. V. Berezkina ◽  
K. V. Shadrina

Relevance. The study of age-related features of microcirculation in periodontal tissues, using non-invasive functional research methods, allows us to develop the optimal range of therapeutic measures, as well as form a “personalized therapeutic case”.Purpose. Study of the functional state of the microvasculature in the tissues of the parodont in individuals of various age groups.Materials and methods. A standard dental examination of 80 patients was carried out, the sample of participants was ranked in 4 groups by age: 1 group – 12 years old, 2 group – 15 years old, 3 group – from 16 to 18 years old, 4 group – from 22 to 24 years old. Hygiene and periodontal indices were determined for all patients, such as papillarymarginal-alveolar (PMA) in the Parma modification, the Mulleman bleeding index in the Cowell modification (SBI), and the simplified Green Vermillion index of oral hygiene (OHI–s), caries intensity indicators for a permanent bite (CPI), as well as ultrasound dopplerography of periodontal tissues using the apparatus "Minimax-Doppler-K".Results. When studying microcirculation in periodontal tissues, distinctive characteristics of linear (Vas) and volumetric (Qas) blood flow rates, as well as indicators of pulsation indices (PI) and peripheral resistance (RI) in people of different age groups were recorded.Conclusions. This study confirms the presence of various hemodynamic indicators of periodontal tissues in the studied groups, which is due to structural features of the circulatory system in age periods.


2015 ◽  
Vol 27 (03) ◽  
pp. 1550021
Author(s):  
S. Mohanalakshmi ◽  
A. Sivasubramanian

Arterial stiffness, resulting in loss of the elastic properties of arteries walls, is an indicator of cardiovascular risk, though the presence of disease is not clinically evident. Augmentation index is an important biomarker of arterial stiffness by which the cardiac risk of the patient can be diagnosed. The current paper outlines the non-invasive assessment of arterial stiffness by analyzing the morphology or contour of PhotoPlethysmoGraph (PPG) signal. PPG pulse was optically acquired with the developed photometric measurement device and the desired features were extracted to determine PPG augmentation Index (PAI) through advanced signal processing implemented in MATLAB. PAI was quantified by the fourth derivative of the signal by enhancing the location of inflection point (augmentation point) after conditioning the signal by efficient pre-processing and filtering techniques. The results reveal that the statistical distribution of PAI for healthy subjects presents a very low value and a very tight distribution. On the contrary, patients have a higher value of PAI and a wide asymmetrical shape of distribution. This work also establishes the usefulness of PPG contour analysis in the investigation of changes in the elastic properties of the vascular system. In conclusion, PAI has revealed to be a non-invasive indicator for arterial stiffness assessments.


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