Malaria vaccination for progressive paralysis

2021 ◽  
Vol 20 (9) ◽  
pp. 994-994
Author(s):  
V. G.
Keyword(s):  
Therapeutic Purpose

Prof. Weygandt (Klin. Woch., 1923, No. 47) reports about 300 cases of progressive paralysis, where it was produced, with a therapeutic purpose, inoculation of malaria (among these cases, about 200 were traced within 1-4 l.).

Ethnobiological knowledge and socio-biodiversity value among Kutia-Kandha tribe of Odisha, India

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Sajan S K
Keyword(s):  
Endangered Species ◽  
Plant Species ◽  
Mammalian Species ◽  
Age Group ◽  
Wildlife Sanctuary ◽  
Medicinal Purpose ◽  
Therapeutic Purpose ◽  
Secondary Sources ◽  
Alternate Source

A study on the socio-biodiversity was conducted in Kotagarh Wildlife Sanctuary (KWS) and nearby areas of Odisha, where the population of Kutia-Kandha tribe is dominant. It was found that, forest has provided tribes with enough materials traditional used for therapeutic purpose. Information from secondary sources by interviews were conducted in eight villages surrounding Kotagarh Wildlife Sanctuary, in which 34 males, 22 females in the age group of 35 -75 and 8 therapeutic practitioners of Kutia-Kandha tribe of Odisha were consulted. The tribes reported 54 different diseases, cured from 52 plant species belonging to 51 genera and 32 families, which are used for ethnomedicinal practices. The Fabaceae found to be the dominant family among plants used for medicinal purpose, whereas for ethnozoological use, a total of 8 mammalian species were used for curing 17 different diseases, most of them are either threatened or endangered species. This paper narrates the enthnobiology and socio-biodiversity aspects of Kutia-Kandha community of Odisha, along with suggestions for alternate source of medicines for the Kutia-Kandha, to reduce dependency on forest produce and reduce hunting of wildlife.

Microscopic and Phytochemical analysis of Desmodium velutinum (Willd) DC and Desmodium gangeticum (L.) DC. Panchanga powder

2021 ◽  
pp. 2950-2956
Author(s):  
Jigyasa Pathak ◽  
Aswathi M. P. ◽  
B. R. Patel ◽  
Harisha C. R. ◽  
Shukla Vinay J.
Keyword(s):  
Chemical Analysis ◽  
Analytical Study ◽  
Water Soluble ◽  
Wild Edible Plants ◽  
Phytochemical Analysis ◽  
Edible Plants ◽  
Therapeutic Purpose ◽  
Whole Plant ◽  
Physico Chemical ◽  
Collection Practices

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum

scholarly journals Technique and Applications of Biofeedback in Photoplethysmography (For the treatment of migraine)

2013 ◽  
pp. 47-50
Author(s):  
Gautham. R. V ◽  
Akshaya. H
Keyword(s):  
Clinical Significance ◽  
Therapeutic Purpose ◽  
New Methods

The correlation of plethysmography with electrocardiography makes us to explore its clinical significance and its application in detection of cardiovascular ailments. But detailed study on plethysmography also helps us to find new methods for therapeutic purpose. One such application is the treatment of Migraine. The technique, procedure, application and biofeedback in Photoplethysmography(PPG) is thoroughly studied and analyzed here.

A Study on the Characteristics of Healthy Volunteers who Participate in Phase I Clinical Trials in Korea

2021 ◽  
pp. 155626462110342
Author(s):  
Ji-Hye Seo ◽  
Ock-Joo Kim ◽  
Sang-Ho Yoo ◽  
Eun Kyung Choi ◽  
Ji-Eun Park
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Phase I ◽  
Healthy Volunteers ◽  
Health Science ◽  
Trial Participation ◽  
Phase I Clinical Trials ◽  
Financial Reward ◽  
Therapeutic Purpose ◽  
The Republic

The phase I trial is the first step in administering a drug to humans, but it has no therapeutic purpose. Under the absence of therapeutic purpose, healthy volunteers demonstrated different motivations, unlike the actual patients participating in trials. There were many reported motivations, such as financial motivation, contributing to the health science, accessing ancillary health care benefits, scientific interest or interest in the goals of the study, meeting people, and general curiosity. The aim of this study was to identify the motivation and characteristics of healthy volunteers participating in phase I trials in the Republic of Korea. We gave surveys to 121 healthy volunteers to study their demographic characteristics and the reasons of participation. We identified whether the decision to participate in the research was influenced by demographic factors and whether the perception and attitudes toward the research were influenced by the characteristics of the healthy volunteers. After completion of the first survey, 12 healthy volunteers who had participated in a phase I clinical trial were selected to answer the second interview. According to our survey, most healthy volunteers were unmarried men and economically dependent. Most of them participated in the study because of financial reward. The most important factor to measure financial reward was the research period. Also, 43% of the volunteers were university students, 42% answered “university graduation” and 55% were residing in family-owned houses. Many healthy volunteers were found to be living in family homes and to have a student status or lack of economic independence. Results of the survey showed that 64% of respondents indicated having more than one clinical trial participation. In-depth interviews showed that healthy volunteers had diverse motivation to participate in research and that healthy volunteer perceive the clinical trial positively. The main motivation for healthy volunteers’ participation in research was “financial reward.” Healthy volunteers also considered research schedules, processes, and safety, and had a positive perception of clinical trials, but they thought that the public has a negative perception.

scholarly journals Targeting autophagy-related protein kinases for potential therapeutic purpose

2020 ◽  
Vol 10 (4) ◽  
pp. 569-581 ◽  
Author(s):  
Honggang Xiang ◽  
Jifa Zhang ◽  
Congcong Lin ◽  
Lan Zhang ◽  
Bo Liu ◽  
...  
Keyword(s):  
Protein Kinases ◽  
Related Protein ◽  
Therapeutic Purpose

scholarly journals Bronchoscopy for Removal of Foreign Body in Lower Airway: A Retrospective Analysis

2019 ◽  
Vol 18 (4) ◽  
pp. 779-782
Author(s):  
Shankar Ramasundram ◽  
Sharmini Kuppusamy ◽  
Sivakumar Kumarsamy ◽  
Valuyeetham Kamara Ambu ◽  
Irfan Mohamad
Keyword(s):  
Foreign Body ◽  
Retrospective Analysis ◽  
High Mortality ◽  
Medical Science ◽  
Lower Airway ◽  
Mortality And Morbidity ◽  
Therapeutic Purpose ◽  
Audit Data ◽  
Duration Of Ventilation

Bronchoscopy is performed for diagnostic or therapeutic purpose. Therapeutic bronchoscopy is mainly done for removal of foreign body from lower airway. Both the condition and procedure itself are associated with high mortality and morbidity. The aim of the study was to audit data regarding demography, types and location of foreign body, onset of symptom, admission duration, clinical and investigation findings along with duration of ventilation. We also highlight on the complications pertaining to the condition in our series. Bangladesh Journal of Medical Science Vol.18(4) 2019 p.779-782  

scholarly journals Next Generation Delivery System for Proteins and Genes of Therapeutic Purpose: Why and How?

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Ashish Ranjan Sharma ◽  
Shyamal Kumar Kundu ◽  
Ju-Suk Nam ◽  
Garima Sharma ◽  
C. George Priya Doss ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Delivery System ◽  
Delivery Systems ◽  
Therapeutic Protein ◽  
Gene Delivery System ◽  
Next Generation ◽  
Therapeutic Purpose ◽  
Detailed Explanation ◽  
Or Gene

Proteins and genes of therapeutic interests in conjunction with different delivery systems are growing towards new heights. “Next generation delivery systems” may provide more efficient platform for delivery of proteins and genes. In the present review, snapshots about the benefits of proteins or gene therapy, general procedures for therapeutic protein or gene delivery system, and different next generation delivery system such as liposome, PEGylation, HESylation, and nanoparticle based delivery have been depicted with their detailed explanation.

scholarly journals Matrix tablet: a review

2018 ◽  
Vol 6 (02) ◽  
pp. 18-22
Author(s):  
D. Prakash Chandra ◽  
R. Archana ◽  
B. Vinoda ◽  
S. Jakir Hussen ◽  
A. Aejaj ◽  
...  
Keyword(s):  
Active Substance ◽  
Matrix Tablet ◽  
Target Tissue ◽  
Therapeutic Purpose ◽  
Delivery Route ◽  
Active Substances

In order to achieve the therapeutic purpose, the choice of the most suitable delivery route is of indisputable importance. Therefore, certain factors must be taken into consideration when delivering a active substance, namely its own properties, the disease to be diagnosed and the desired beneficial time. The active substances can be directly to the target tissue or organ or can be delivered by systemic routes.

scholarly journals Verification of Internal Oleation Doses mentioned by Vangasena to achieve proper Oleation before Vamana and Virechana

2015 ◽  
Vol 6 (3) ◽  
Author(s):  
Vishakha Rajesh Wetal
Keyword(s):  
Maximum Dose ◽  
Objective Evaluation ◽  
Therapeutic Purpose ◽  
Time Required ◽  
Medium Dose

Background -Maximum(Pradhan), minimum(heena) and medium(madhyam) doses for  internal oleation pursued as preparation, before Vamana (induced vomiting for therapeutic purpose) and Virechana (induced purgation for therapeutic purpose) is mentioned in all three Ayurveda classic texts (Brihat-trayi), on the basis of time required for its digestion and doshavastha.. This method is very subjective contrary to the objective evaluation affirmed in Vangasen-Snehpanadhikar(VS), where evaluator does not make any judgment. The actual dose quantification, in increasing order for shodhan purpose is mentioned in VS. Objective-To verify suitability of internal oleation doses cited in Vangasen to achieve Samyak Snigdha Lakshanani(SSL) and to monitor its complications if any.    Method - This method was applied for 18 patients intended for either Vamana or Virechana to verify its authenticity to achieve SSL. Sixteen patients were given medium dose and two were given maximum dose. Oleation was discontinued as soon as SSL were achieved.Result-Out of 18 patients one achieved SSL in three days, five in four days, six in five days and five patients in six days. One patient took seven days to achieve SSL. Out of 18 patients, on last day one digest sneha in 2 hrs, 3 digest it in 4 to 5 hrs, 9 in 6 to 7 hrs, and 5 patients took 10 to 15 hrs to digest sneha on the day of completion of Snehana. Complications were not observed in any patient.Conclusion-Medium or maximum doses specified in VS, can be used for internal oleation before Vamana and Virechana to achieve SSL without any complication. Thus the method is practical one. 

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