Characteristic of the immune status in persons working with videoterminals

1993 ◽  
Vol 74 (3) ◽  
pp. 220-222
Author(s):  
N. H. Amirov ◽  
L. M. Fatkhutdinova ◽  
V. N. Krasnoshchokova
Keyword(s):  
Immune System ◽  
Psychosocial Factors ◽  
Immune Complexes ◽  
Immune Status ◽  
Work Satisfaction ◽  
Circulating Immune Complexes ◽  
Considerable Influence ◽  
Basic Group

The content of immunoglobulins (IgG, IgA, IgM) as well as circulating immune complexes (CIC) is determined in the blood scrum of 58 programmers working with videodisolay terminals (VDT) and 19 employees not working or seldom using VDT. The higher IgG and IgA levels are revealed, with most of the persons having the exceeding norm of IgA and CIC values in the basic group. The considerable influence of work satisfaction on IgA and IgM levels and expression degree of working and chronic organization stress on CIC levels is revealed: index levels being lower at work satisfaction and at low values of stress scales. The influence of the electromagnetic 9200 kHz range fields on the indices of the immune status is not detected. It is concluded that the immune system is made more active at work with VDT and the psychosocial factors are of great importance in this process.

scholarly journals Influence of Melatonin on the state of immunity at psoriasis

2009 ◽  
Vol 8 (4) ◽  
pp. 148-151
Author(s):  
V. S. Dmitruk ◽  
L. V. Striga
Keyword(s):  
Immune System ◽  
Polyethylene Glycol ◽  
Immune Complexes ◽  
Combined Treatment ◽  
Circulating Immune Complexes ◽  
Selective Precipitation ◽  
Exogenous Melatonin ◽  
Immunomodulatory Action ◽  
Immunofluorescent Method

The influence of the chronopharmacological scheme of treatment with the use of exogenous Melatonin in the form of the Melaksen drug on the immunity status of psoriasis patients has been studied. The study of the immunity status consisted in determination of the main Manchini classes of immunoglobulins A, M, G, the level of circulating immune complexes by the method of selective precipitation in 3% polyethylene glycol. In addition, we determined the subpopulation of lymphocytes carrying CD3, CD4, CD8, CD16, CD 25, and CD72 antigens by the immunofluorescent method. In has been found that Melatonin in psoriasis patients exerts the immunomodulatory action on the immune system at the combined treatment (due to an increase in the number of -lymphocytes with cytotoxic-suppressive properties at obvious signs of immune disbalance in the form of the increased ratio of Т CD4+ and CD8+).

Dynamics of immunologic parameters in elder children with atopic dermatitis

1999 ◽  
Vol 80 (4) ◽  
pp. 253-255
Author(s):  
В. А. Shamov ◽  
A. G. Shamova ◽  
T. G. Malanicheva
Keyword(s):  
Atopic Dermatitis ◽  
Immune Complexes ◽  
Immune Status ◽  
Circulating Immune Complexes ◽  
Natural Killers ◽  
Cd8 Cells ◽  
Immunologic Parameters

In children aged 10 to 17 with atopic dermatitis the following changes are revealed: the decrease of the content of CD3+-cells, CD8+-cells, natural killers, CH50, the increase of immunoregulator index indicators, CD19+-cells, igg, ige circulating immune complexes. More pronounced disorders of the immune status are found in boys and girls aged 13 to 17 than in children aged 10 to 12. After the treatment the favourable dynamics of the indicators of CD8+-cells, immunoregulator index, concentration of igg, ige and circulating immune complexes is found.

scholarly journals ОСОБЛИВОСТІ ІМУННОГО ГОМЕОСТАЗУ В ДИНАМІЦІ РОЗВИТКУ ЕКСПЕРИМЕНТАЛЬНОЇ БРОНХІАЛЬНОЇ АСТМИ

2018 ◽  
Author(s):  
M. S. Reheda ◽  
L. A. Lubinets ◽  
B. F. Shchepanskyi
Keyword(s):  
Immune System ◽  
B Lymphocytes ◽  
Immune Complexes ◽  
Guinea Pigs ◽  
Circulating Immune Complexes ◽  
System Response ◽  
Control Group ◽  
Modeling Process ◽  
Immune System Response

In this paper, it is shown that the modeling process of bronchial asthma (BA ) is accompanied by changes, in comparison with the control group, in the indicators of immune system response: T- & B-lymphocytes, circulating immune complexes in blood of guinea pig males on the 4th, 18th, 25th day of experiment.The aim of the study – determination of some indices of immune system in blood of guinea pigs in the modeling process of BA on 4th, 18th, 25th day of the experiment.Materials and Methods. Experiments were conducted on 40 guinea pigs (males), with body weight 0.25–0.27 kg. Animals were divided into four groups of ten animals in each. Intact guinea pigs were the first group. Animals with experimental BA – the second, third, fourth group respectively on the 4th, 18th, 25th day of the experiment. Experimental BA was reproduced by V. I. Babych method. In blood of intact guinea pigs and animals with experimental BA , the number of T- and B-lymphocytes was determined by the method of E. F. Chernushenko, L. S. Kohosov, determination of the level of circulating immune complexes was carried out by the method of V. Haskova and co-authors. The results of the study were processed by the method of variation statistics using Student's criterion.Results and Discussion. The results of the studies showed unidirectional changes in individual parameters of the immune system, depending on the periods of the formation of BA : an increase in the number of B-lymphocytes and circulating immune complexes, a decrease in the number of T-lymphocytes for all of the studied days of the experiment.Conclusions. The obtained results indicate significant changes in the immune system parameters in the blood of experimental animals with BA and are important for understanding the pathogenesis of BA . These studies provide an opportunity to find the more perfect and effective methods of diagnosis of BA.

scholarly journals The effect of interferons-α and –γ and their combination with dimethyl dipyrazolyl selenide on the immune status and functional state of the reproductive system of cows in adverse ecological conditions

2019 ◽  
pp. 53-57
Author(s):  
A. G. Shakhov ◽  
I. T. Shaposhnikov ◽  
Yu. N. Brigadirov ◽  
V. N. Kotsarev ◽  
V. N. Skorikov ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Functional State ◽  
Reproductive System ◽  
Immune Complexes ◽  
Immune Status ◽  
Lysozyme Activity ◽  
Circulating Immune Complexes ◽  
Control Group ◽  
Ecological Conditions ◽  
Positive Effect

The results of studying the effect of interferons alpha and gamma and their combination with dimethyl dipyrazolyl selenide on the immune status and functional state of the reproductive system of cows in adverse ecological conditions are presented. The positive effect of the drugs, especially their combination, on erythropoiesis and the immune status of animals, which was manifested by an increase in the content of erythrocytes, hemoglobin, hematocrit, leukocytes, total immunoglobulins, serum bactericidal and lysozyme activity, absorptive function of phagocytes, relative amount of T lymphocytes, and a decrease in the level of circulating immune complexes was stated. An increase in the immune status of animals at the effect of immunocorrecting drugs was accompanied by a decrease in the pathology of calving and postpartum complications and favorably affected the functional state of their reproductive system. The cows which were introduced interferons and their combination with dimethyl dipyrazolyl selenide demonstrated a shorter period from calving to successful insemination, as well as the insemination index and fertility, compared with the animals of the control group, which were not introduced any drugs.

scholarly journals Clinical and immunological features of opisthorchiasis

2021 ◽  
Vol 102 (5) ◽  
pp. 626-635
Author(s):  
A U Sabitov ◽  
D A Soldatov ◽  
Yu B Khamanova
Keyword(s):  
Immune System ◽  
Immune Complexes ◽  
Statistical Significance ◽  
Rank Correlation ◽  
Statistical Processing ◽  
Circulating Immune Complexes ◽  
Control Group ◽  
Cytotoxic Lymphocytes ◽  
Spearman’S Rank Correlation ◽  
Diagnostic Center

Aim. To assess the clinical and immunological features in patients with chronic opisthorchiasis, depending on the duration of the infection. Methods. The first group consisted of 19 patients with the duration of the infection up to 1 year, the second group consisted of 21 patients with the duration of the infection between 1 and 5 years, the third group was formed of 23 patients with the duration of the disease more than 5 years, the control group 20 healthy individuals. Immunological research was carried out at the Clinical Diagnostic Center. Statistical processing was performed using Microsoft Excel 2010 and Statistica 6.0 software. The statistical significance of differences was determined by using the MannWhitney test (U-test) at the level of significance of p 0.05. The correlations were assessed by calculating Spearman's rank correlation coefficients.Results Clinical features of chronic opisthorchiasis were revealed in the disease duration groups of up to 1 year, from 1 year to 5 years, more than 5 years: the subclinical course was most common in the group of up to 1 year; cholangiohepatitis prevailed in the group of between 1 to 5 years, allergic skin syndrome, cholangiocholecystitis and pancreatitis dominated in the group of more than 5 years. The immune response in chronic opisthorchiasis was characterized by: up to 1 year lymphocytosis, increased levels of immunoglobulins M (IgM) and circulating immune complexes (CIC), a decrease in the number of T-lymphocytes (CD3+), as well as an increase in bactericidal activity of leukocytes (BAL); between 1 and 5 years monocytosis, increased levels of immunoglobulins M, immunoglobulins G and circulating immune complexes, a decrease in T-cytotoxic lymphocytes (CD8+) and nitro blue tetrazolium (NBT test), as well as an increase in NK cells and phagocytic activity of monocytes, more than 5 years eosinophilia. Conclusion. Common features of rearrangement of the immune system in opisthorchiasis: inflammatory changes in the hemogram, activation of humoral immunity with parallel suppression of the cellular component of the immune system, and increased phagocytosis.

scholarly journals Immune related prognosis biomarkers for outcomes of joint preservation surgery in children with ischemic deformity of the proximal femur (preliminary results)

2020 ◽  
Vol 26 (4) ◽  
pp. 516-520
Author(s):  
M.P. Teplenky ◽  
◽  
M.V. Chepeleva ◽  
E.I. Kuznetsova ◽  
◽  
...  
Keyword(s):  
Proximal Femur ◽  
Immune Complexes ◽  
Immune Status ◽  
Circulating Immune Complexes ◽  
Immunological Parameters ◽  
Humoral Immune ◽  
Joint Preservation ◽  
Group I ◽  
Low Levels ◽  
Group Ii

Objective Assess the immune status of children with ischemic deformity of the proximal femur taking into account the treatment outcome. Material and methods Preoperative assessment of the immune status was performed for 16 adolescents with ischemic deformity of the proximal femur. Patients' age was 14.4 ± 0.45 years. Immunological parameters of 12 adolescents with satisfactory (group I) and 4 patients with poor (group II) anatomical and functional outcome of surgical treatment were compared. Peripheral blood lymphocyte typing was produced with laser cytometry assay, and IgA, IgM, IgG, IgE, IL-18, IFNγ and circulating immune complexes were quantified with enzyme-linked immunoassay. Results Сomparative analysis of preoperative immunological parameters showed statistically significant decline of Т-helper cells (СD3+СD4+), high levels of activated СD3+CD25 and СD3+HLADR T lymphocytes, low levels of activated NК cells (СD8dimCD38+) and IFNγ in group II. Humoral immune parameters indicated to low levels of IgA, IgM, IgG and higher levels of circulating immune complexes in group II relative to group I. Conclusion Preliminary data obtained suggest that cellular and humoral immune deficiency can be associated with unfavorable outcome of joint preservation procedure. Such immunological parameters as T lymphocytes subpopulation, immunoglobulins, circulating immune complexes and IFNγ can be used as significant prognostic factors for preoperative planning and postoperative rehabilitation of adolescents with ischemic deformity of the proximal femur.

scholarly journals Immune complexes in blood serum of calves with clinical symptoms of bronchopneumonia

2011 ◽  
Vol 65 (1-2) ◽  
pp. 13-24
Author(s):  
Natalija Fratric ◽  
Dragan Gvozdic ◽  
Olivera Savic ◽  
Ivana Jaglicic ◽  
Vesna Ilic
Keyword(s):  
Immune Complexes ◽  
Immune Status ◽  
Clinical Symptoms ◽  
Electrophoretic Analysis ◽  
Circulating Immune Complexes ◽  
Infectious Agents ◽  
Diagnostic Parameter ◽  
Environment Management ◽  
Additional Diagnostic Parameter

Pneumonia in preruminant calves is a multifactorial disease. Infectious agents, the environment, management and the immune status of the calves are all important factors in determining the outcome of an infection. Until today, the level and composition of circulating immune complexes in preruminant calves with pneumonia have not been studied in detail. We performed this work with the aim to determine whether pneumonia in three-month-old calves is followed by changes in the immune complex level and changes in the ?-globulin level as their possible constituents. Immune complexes from the calves? sera were isolated by polyethylene glycol (PEG) precipitation methods. Optical density at 350 nm (OD350) of redissolved precipitates was measured to determine the circulating immune complexes level. The OD350 level of PEG precipitates of calves with pneumonia at the time of diagnosis was 0.577?0.206 and it was statistically significantly higher (p<0.001) than OD350 the level of PEG precipitates of healthy calves (0.286?0.080). Electrophoretic analysis of sera and PEG precipitates showed that both slow and fast ?-globulins are found among serum and immune-complexes' ?-globulins, but the concentration of fast ?-globulins was significantly lower in sera of diseased calves. The level of PEG precipitable immune complexes was not correlated with the concentration of serum and PEG precipitable g-globulins. The results of this study have shown that by relatively simple PEG precipitation assay it is possible to detect an increased level of circulating immune complexes in calves with pneumonia. This can be used as an additional diagnostic parameter for the detection and follow up of the disease.

Assessment of the immunological status in patients of a surgical hospital

1993 ◽  
Vol 74 (3) ◽  
pp. 218-219
Author(s):  
I. V. Klyushkin ◽  
E. E. Krasnoshchekova ◽  
K. T. Valeeva ◽  
M. N. Nasrullaev
Keyword(s):  
Immune System ◽  
Blood Serum ◽  
Conventional Method ◽  
Bactericidal Activity ◽  
Immune Complexes ◽  
Clinical Picture ◽  
Circulating Immune Complexes ◽  
Immunological Status ◽  
Serum Immunoglobulins

In patients with a surgical profile, the humoral link of the immune system was studied for the production of 3 classes of immunoglobulins (IgA, IgM, IgG), the formation of circulating immune complexes (CIC), bactericidal activity of blood serum (BASK) in comparison with the clinical picture of the disease. Serum immunoglobulins were determined according to Mancini, CEC by the conventional method according to D. K. Novikov (1987), BASK by the method of V. I. Nikitenko and O. V. Bukharin.

scholarly journals Порушення імунного гомеостазу в ранній період розвитку виразкової хвороби шунка на тлі експериментальної пневмонії

2017 ◽  
Author(s):  
L. O. Furdychko
Keyword(s):  
Gastric Ulcer ◽  
Immune System ◽  
T Lymphocytes ◽  
B Lymphocytes ◽  
Immune Complexes ◽  
Experimental Studies ◽  
Early Period ◽  
Circulating Immune Complexes ◽  
Immune Homeostasis ◽  
Experimental Pneumonia

Introduction. The article adduces the obtained results of the indices of immune homeostasis in the development of combined pathology (experimental pneumonia (EP) and gastric ulcer (GU) of the stomach). The immune system is characterized by the number of T-lymphocytes since they are the basis of the cellular component of the immuneresponse and the concentration of b-lymphocytes and circulating immune complexes (CIC), which are responsible for cellular immunity.The aim of the study – the content of T-lymphocytes, CEC to assess the immune system in the development of EP and GU.Materials and Methods. This experimental study was conducted on 39 guinea pigs-males. Experimental pneumonia caused by the method of V. N. Shliapnikova, T. L. Solodova [et al.] Gastric ulcer of the stomach wassimulated by the method of V. I. Komarova. We determined the content of T- and B-lymphocytes (SD3 and SD19) in the blood by the method of E. F. Chernushenko, L. S. Kohosova. The level of circulating immune complexes (CIC) in the blood by the method of Haskova V., Kaslik J..Results and Discussion. The results of experimental studies established that early period of development (4th and 8th day) of gastric ulcer and pneumonia is characterized by the following changes of immune homeostasis: decrease in the level of T-lymphocytes and elevated levels of lymphocytes and circulating immune complexes in the blood of Guinea pigs.Conclusion. A depression of cell growth and humoral types of immunity in terms of experimental pneumoniaand gastric ulcer was revealed.  

scholarly journals The evolution of the immune status in patients with chronic obstructive pulmonary disease after using enterosorption

2015 ◽  
Vol 17 (3) ◽  
Author(s):  
S. V. Lototska ◽  
S. M. Andreychyn ◽  
V. M. Meretskyi
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Immune Complexes ◽  
Immune Status ◽  
Immunoglobulin E ◽  
Circulating Immune Complexes ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Serum Lysozyme ◽  
Positive Effect

<p>The are presented the results of research indicators of immunological status in patients with chronic obstructive<br />pulmonary disease after incluing in the complex therapy of diseases enterosorbents “Enterosgel” or “Karbolayn”.<br />Received results showed that the disease is accompanied by increased levels of circulating immune complexes<br />and immunoglobulin E content and a decrease in serum lysozyme. Enterosorption marked positive effect on the<br />background of the basic treatment of patients with chronic obstructive pulmonary disease as evidenced by the reduction<br />of circulating immune complexes and immunoglobulin E and rising of lysozyme. After conducting a comparative<br />analysis of two sorbents we found that carbon sorbent was more efficient.</p>

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