External respiration function in children with atopic dermatitis

1998 ◽  
Vol 79 (4) ◽  
pp. 282-285
Author(s):  
A. M. Potemkin ◽  
T. V. Klykova ◽  
I. A. Blonde
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Preventive Measures ◽  
External Respiration ◽  
Respiration Function

The data on the frequency of revealing the bronchial permeability disorders are presented and the mechanisms of its development in children with atopic dermatitis not having clinically bronchoobstructive syndrome in anamnesis are studied. In children with atopic dermatitis the main risk factors of the bronchial asthma development are shown and the possibilities of revealing its early preclinical signs are determined. It is significant in prevention of the bronchial asthma development in timely performance of specific preventive measures.

scholarly journals Clinical and laboratory features in young patients with bronchial asthma and obesity

2015 ◽  
Vol 12 (5) ◽  
pp. 9-16
Author(s):  
I V Demko ◽  
E A Sobko ◽  
I A Soloveva ◽  
A Yu Kraposhina ◽  
O P Ishenko ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Cellular Structure ◽  
Young Patients ◽  
External Respiration ◽  
Laboratory Features ◽  
Alimentary Obesity ◽  
Functional Features ◽  
Body Weight Index ◽  
Respiration Function ◽  
Healthy Persons

Background. To study the clinical and functional features in interrelationship between the level of proinflammatory and antiinflammatory cytokines in young patients with bronchial asthma and alimentary obesity for optimization of therapy. Methods. 133 persons were examined: 93 patients with bronchial asthma were divided into 2 groups depending on body weight index (BWI): the 1st group included patients with bronchial asthma with BWI less than 25 kg/m2, the 2nd group included patients with bronchial asthma with BWI 30 kg/m2 and more. The group of control included 40 almost healthy persons. We studied external respiration function, cellular structure of the induced sputum, the level of TNFα, IL-2, IL-4, IL-6, IL-15, Creactive protein in blood. Results. The results of cytokines at patients with bronchial asthma depending on BWI out of an exacerbation of the disease within the last 2 months. We found the signs of more significant systemic inflammation in the group with obesity the increasing of the level of IL2, IL6, TNFa and Creactive protein in plasma was found. Conclusion. We found that there was more sever course of bronchial asthma in young patients with obesity, decreased external respiration functions, increased level of proinflammatory cytokines and proteins of acute phase in peripheral blood.

From atopic dermatitis to asthma: The risk factors and preventive measures

1997 ◽  
Vol 23 (S16) ◽  
pp. 19-20 ◽  
Author(s):  
L. Businco ◽  
P. Falconieri ◽  
A. Di Rienzo ◽  
G. Bruno
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Preventive Measures

scholarly journals Pulmonary hypertension in patients with systemic scleroderma

2017 ◽  
Vol 94 (12) ◽  
pp. 918-923
Author(s):  
N. A. Karoli ◽  
Andrei P. Rebrov
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypertension ◽  
Clinical Features ◽  
Clinical Condition ◽  
Regional Hospital ◽  
Systemic Scleroderma ◽  
Advanced Age ◽  
External Respiration ◽  
Left And Right ◽  
Respiration Function

Aim. To evaluate the frequency of pulmonary hypertension (PH) in patients with systemic scleroderma (SSD) and elucidate clinical features of SSD with and without concomitant PH. Materials and methods. The study included 206 patients (189 women and 17 men) with SSD treated in Rheumatological Department, Saratov Regional Hospital. Clinical features, results of echocardiography and external respiration function (ERF) studies were analyzed in SSD patients with and without concomitant PH. Results. PH was documented in 33% of the patients. Their clinical condition, changes in left and right hear as well as ERF were elucidated. Conclusion. The study confirmed the high informative value of echocardiography used to evaluate ERF in patients with SSD and the possibility to apply this method for screening PH in SSD patients. The risk factors of PH in SSD patients include advanced age, apnoea, disturbed ERF, and sclerodactylia.

Atopic dermatitis: new horizons of therapy

2019 ◽  
Vol 1 (7) ◽  
pp. 29-32 ◽  
Author(s):  
L. S. Kruglova ◽  
E. M. Gensler
Keyword(s):  
Blood Pressure ◽  
Immune Response ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Targeted Therapy ◽  
Inflammatory Response ◽  
Bronchial Asthma ◽  
New Horizons ◽  
The Past

Over the past decades, the first breakthrough milestone in the treatment of severe forms of atopic dermatitis (AD) has been targeted therapy aimed at inhibiting IL-4 and IL-13. This was made possible thanks to advances in the understanding of the pathogenesis of AD, the driver of which is the Th2-type immune response, which also underlies such manifestations of atopy as bronchial asthma, allergic rhinitis, and polynosis. In the case of the Th2-type immune response, cytokines IL-4 and IL-13 are secreted, which are the main promoters of the inflammatory response in AD. Inhibition of IL-4 and IL-13 leads to the prevention of inflammation and is an effective approach to therapy. The use of therapy aimed at inhibition of cytokines allows you to effectively cope with the manifestations of severe and moderately severe blood pressure.

Graft detachments in endothelial keratoplasty

2021 ◽  
pp. bjophthalmol-2020-318092
Author(s):  
Rashmi Deshmukh ◽  
Sridevi Nair ◽  
Darren Shu Jeng Ting ◽  
Tushar Agarwal ◽  
Jacqueline Beltz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preventive Measures ◽  
Endothelial Keratoplasty ◽  
Common Complication ◽  
Prevention Measures ◽  
Descemet Stripping Endothelial Keratoplasty ◽  
Secondary Interventions ◽  
Different Types ◽  
Incidence Risk ◽  
Donor Graft

Graft detachment is the most common complication of endothelial keratoplasty. With the ongoing advancements in the field of endothelial keratoplasty, our understanding of risk factors of graft detachments and its management has been evolving. Various prevention measures have been described in literature including presoaking the donor graft, anterior chamber tamponade, venting incisions, sutures to prevent dislocation of graft. Management of a detached graft involves secondary interventions such as rebubbling, suturing and regrafts. In this review, we discuss graft detachment in different types of endothelial keratoplasty techniques including Descemet stripping endothelial keratoplasty, Descemet stripping automated endothelial keratoplasty and Descemet’s membrane endothelial keratoplasty; with emphasis on incidence, risk factors, preventive measures and their management.

scholarly journals Analysis of Risk Factors for African Swine Fever in Lombardy to Identify Pig Holdings and Areas Most at Risk of Introduction in Order to Plan Preventive Measures

Pathogens ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1077
Author(s):  
Silvia Bellini ◽  
Alessandra Scaburri ◽  
Marco Tironi ◽  
Stefania Calò
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
European Union ◽  
Preventive Measures ◽  
Descriptive Analysis ◽  
African Swine Fever ◽  
The European Union ◽  
Z Score ◽  
Pork Products ◽  
Pig Farms

In 2019, the area of the European Union (EU) affected by African swine fever (ASF) expanded progressively in a southwestern direction from Baltic and eastern countries. The disease can severely affect and disrupt regional and international trade of pigs and pork products with serious socioeconomic damages to the pig industry. Lombardy is one of the most important European pig producers and the introduction of ASF into the pig population could adversely affect the entire sector. A study was carried out to identify the farms and territories in the region most at risk of ASF introduction to plan preventive measures. The pig holdings were identified through a descriptive analysis of pig movements and Social Network Analysis (SNA), while, for the identification of the most exposed municipalities, an assessment of risk factors was carried out using the ranking of summed scores attributed to the Z-score. From the analysis, it was found that 109 municipalities and 297 pig holdings of the region were potentially more at risk, and these holdings were selected for target surveillance. This information was provided to veterinary authority to target surveillance in pig farms, in order to early detect a possible incursion of ASF and prevent its spread.

Risk factors associated with toxoplasmosis and toxocariasis in populations of children from nine cities in southern Brazil

2014 ◽  
Vol 89 (4) ◽  
pp. 428-432 ◽  
Author(s):  
A.A. Marchioro ◽  
C.M. Colli ◽  
É.C. Ferreira ◽  
B.M. Viol ◽  
S.M. Araújo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preventive Measures ◽  
Enzyme Linked Immunosorbent Assay ◽  
Multiple Logistic Regression ◽  
Southern Brazil ◽  
Parasite Control ◽  
Igg Antibodies ◽  
Positive Serology ◽  
Factors Associated ◽  
Epidemiological Factors

AbstractThis study investigated the epidemiological factors that contribute to the seroprevalence of Toxoplasma gondii and Toxocara spp. in children from Paraná state, Brazil. Immunoglobulin G (IgG) antibodies to T. gondii were detected using indirect immunofluorescence, and IgG antibodies to Toxocara were detected using an enzyme-linked immunosorbent assay. For each individual, a questionnaire was completed that contained epidemiological and clinical data. The data analysis was performed using multiple logistic regression. Of the 544 children investigated, 3.2% presented co-infection with T. gondii and Toxocara spp. Of this total, 7.4% were positive for antibodies to T. gondii, and 25% were positive for antibodies to Toxocara spp. The presence of antibodies to Toxocara spp. increased the risk of T. gondii infection (P= 0.029). Children who were 1–8 years of age were less infected by T. gondii than those who were 9–12 years of age. The variables that influenced positivity for anti-Toxocara spp. were the origin of the children and contact with sand. Children with positive serology for Toxocara spp. presented more eosinophilia compared with those with non-reactive serology. Infection with both parasites reveals the need for preventive measures, such as guidance about modes of infection, parasite control and monitoring recreational areas.

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