Results of clinical observations of the course of female genital gonorrhea processes under the control of the Bordet-Gengou reaction

1936 ◽  
Vol 32 (7) ◽  
pp. 853-857
Author(s):  
N. A. Lvov
Keyword(s):  
Blood Serum ◽  
Diagnostic Method ◽  
The Body ◽  
Foreign Protein ◽  
Serological Method ◽  
Scientific Thought ◽  
Specific Antibodies ◽  
Clinical Observations ◽  
Female Genital

Due to special difficulties often associated with complicated diagnostics, the so-called. closed gonorrhea of ​​the female genital organs with the presence of encapsulated foci in them, the scientific Thought of the researchers was tirelessly directed towards the search for such a diagnostic method that the establishment of the gonorrhea etiology of the disease would be beyond any doubt. One of these methods is the serological method, based on the well-known phenomenon discovered by the Belgian scientists Bogdet and Gengou in 1898. Its essence lies in the fact that specific antibodies are formed in the blood serum of an animal to which a foreign protein is parenterally administered. The detection of these specific antibodies in the blood serum of an animal makes it possible to judge the penetration of certain microbes into the body. This serological method, called the Bordet-Gengou reaction (B. G.), has now become widespread in the clinic of female gonorrhea and has the same significance for recognizing gonorrhea as Wasserman's reaction in syphilis.

scholarly journals The formation of colostral immunity and its duration in calves during the first months of life

2019 ◽  
Vol 2 (1) ◽  
pp. 3-6
Author(s):  
D. M. Masiuk ◽  
A. V. Kokariev ◽  
T. O. Vasilenko ◽  
K. O. Krutii
Keyword(s):  
Blood Serum ◽  
The Body ◽  
Specific Antibodies ◽  
Viral Diarrhea ◽  
Newborn Calves

The paper presents the results of a study on the formation of colostral immunity and the determination of its duration during the first months of life of calves according to the indications of the level of total IgG and antigen-specific antibodies to pathogens of рarainfluenza 3, respiratory syncytial infection and viral diarrhea of cattle. It has been established that blood serum of newborn calves does not contain antigen-specific immunoglobulins of class G to pathogens of viral diarrhea, respiratory syncytial infection and parainfluenza-3, and the level of total IgG is 2.2 ± 0.61 g/dm3. The concentration of total IgG is increased to 50.50 ± 6.33 g/dm3, and decreases to 27.25 ± 5.82 g/dm3 for 28 days, which contributes to the formation of the immunosuppressive state at the 7th day of a calf life. Starting from 35th day, there is an increase in the concentration of total IgG due to seroconverting of its own antibodies by the body of calves. Immunization of cows-mothers against viral diarrhea, respiratory syncytial infection and parainfluenza-3 contributes to the formation of antigen-specific colostral immunity in calves in the first days of life, which is preserved in diagnostic titers during 63 days after birth.

Possibilities for treating aspirin-i lesions of the stomach and duodenum in patients with chronic coronary heart disease

2020 ◽  
Vol 98 (3) ◽  
pp. 231-235
Author(s):  
N. Yu. Borovkova ◽  
M. V. Buyanova ◽  
T. E. Bakka ◽  
M. P. Nistratova ◽  
T. V. Vlasova ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Proton Pump Inhibitor ◽  
Blood Serum ◽  
Proton Pump ◽  
The Body ◽  
Control Group ◽  
Pge2 Level ◽  
Endogenous Prostaglandins ◽  
Chronic Coronary Heart Disease

To evaluate possibilities of aspirin-induced gastroduodenopathy treatment in the patients with chronic ischemic heart disease by means of applying the internal endogenous prostaglandins stimulant.  Material and methods. 340 patients suffering from chronic coronary heart disease and receiving a long-term acetylsalicylic acid (ASA) therapy were examined on the base of the cardiovascular care unit of The Nizhny Novgorod Regional Clinical Hospital named after N.A. Semaschko. There were evaluated frequency, nature and severity of the aspirin-induced gastroduodenopathy. The patients with coronary heart disease and aspirin-induced gastroduodenopathy were divided in two groups. In the first group of patients there was applied rebamipide therapy (in a single daily dose 300 mg) in combination with the proton pump inhibitor (PPI) — pantoprazole. In the second group there was applied only pantoprazole therapy. For the purpose of specification of AIG pathogenetic mechanisms development, all the examined chronic coronary heart disease cases were tested on the prostaglandin E2 (PGE2) level in blood serum before the therapy beginning and after the treatment. The control group was formed of chronic coronary heart disease patients showing no AIG evidence. Statistical processing of the received data was fulfilled with the program «Statistika 10.0». Results. AIG was registered in 15% out of 340 chronic coronary heart disease patients. According to the endoscopic examination erosive disease of the body and antrum prevailed among the patients. The PGE2 level in the blood serum was significantly lower (р = 0,00087) in these patients in comparison with the control group. In association with PPI and rebamipide mixed therapy, esophagogastroduodenoscopy results showed no pathological findings in gastrointestinal mucosa and statistically significant (р = 0,00067) blood serum PGE2 level growing in all the treated patients. As a result of exclusive PPI therapy there was marked positive dynamics in endoscopic view in 19 out of 25 patients and a tendency to normalization of PGE2 level in the blood serum. However, PGE2 level growing was insignificant. Conclusion. The presented research demonstrates the possibility of AIG treatment with the use of internal endogenous prostaglandins stimulant — rebamipide in complex with proton pump inhibitor PPI therapy.

scholarly journals Severe Fever with Thrombocytopenia Syndrome in Cats and Its Prevalence among Veterinarian Staff Members in Nagasaki, Japan

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1142
Author(s):  
Tsuyoshi Ando ◽  
Takeshi Nabeshima ◽  
Shingo Inoue ◽  
Mya Myat Ngwe Tun ◽  
Miho Obata ◽  
...  
Keyword(s):  
Cell Cultures ◽  
Phylogenetic Analyses ◽  
The Body ◽  
Virus Growth ◽  
Specific Antibodies ◽  
Staff Members ◽  
Zoonotic Risk ◽  
Sentinel Animals ◽  
Animal Care ◽  
Severe Fever

In this study, we investigated severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) infection in cats in Nagasaki, Japan. In total, 44 of 133 (33.1%) cats with suspected SFTS were confirmed to be infected with SFTSV. Phylogenetic analyses of SFTSV isolates from cats indicated that the main genotype in Nagasaki was J1 and that unique reassortant strains with J2 (S segment) and unclassified genotypes (M and L segments) were also present. There were no significant differences in virus growth in cell cultures or fatality in SFTSV-infected mice between the SFTSV strains that were isolated from recovered and fatal cat cases. Remarkably, SFTSV RNAs were detected in the swabs from cats, indicating that the body fluids contain SFTSV. To evaluate the risk of SFTSV infection when providing animal care, we further examined the seroprevalence of SFTSV infection in veterinarian staff members; 3 of 71 (4.2%) were seropositive for SFTSV-specific antibodies. Our results provide useful information on the possibility of using cats as sentinel animals and raised concerns of the zoonotic risk of catching SFTSV from animals.

scholarly journals A REPORT ON ANTIMENINGITIS VACCINATION AND OBSERVATIONS ON AGGLUTININS IN THE BLOOD OF CHRONIC MENINGOCOCCUS CARRIERS

1918 ◽  
Vol 28 (4) ◽  
pp. 449-474 ◽  
Author(s):  
Frederick L. Gates
Keyword(s):  
Blood Serum ◽  
Salt Solution ◽  
Blood Stream ◽  
Severe Reaction ◽  
Meningeal Irritation ◽  
Specific Antibodies ◽  
Individual Susceptibility ◽  
Normal Controls

1. A meningococcus vaccine suspended in salt solution has been given subcutaneously as a prophylactic to about 3,700 volunteers in three injections of 2,000 million, 4,000 million, and 4,000 or 8,000 million cocci at weekly intervals. 2. These doses rarely caused more than the mildest local and general reactions. Exceptionally a more severe reaction emphasized the presence of an unusual individual susceptibility to the vaccine. In such instances the symptoms were in part those of meningeal irritation and sometimes simulated the onset of meningitis. 3. Specific meningococcus agglutinins have been demonstrated in the blood serum of vaccinated men as compared with normal controls. 4. Moreover, agglutinins have been demonstrated in the blood serum of chronic carriers of the meningococcus. Evidence is thus brought forward that the relative immunity of chronic carriers to epidemic meningitis may be due to the presence of specific antibodies in the blood stream.

scholarly journals The Limits of Constructivism: Can Rawls Condemn Female Genital Mutilation?

2009 ◽  
Vol 71 (3) ◽  
pp. 459-482 ◽  
Author(s):  
Andrew Koppelman
Keyword(s):  
John Rawls ◽  
The Body ◽  
Political Life ◽  
The Good Life ◽  
Political Aspect ◽  
Genital Mutilation ◽  
Theory Of Justice ◽  
The Face ◽  
Acceptable Theory ◽  
Female Genital

AbstractConstructivist political theory, championed most prominently by John Rawls, builds up a conception of justice from the minimal requirements of political life. It has two powerful attractions. It promises a kind of civic unity in the face of irresolvable differences about the good life. It also offers a foundation for human rights that is secure in the face of those same differences. The very parsimony that is its strength, however, deprives it of the resources to condemn some atrocities. Because it focuses on the political aspect of persons, it has difficulty cognizing violence done to those aspects of the person that are not political, preeminently the body. Constructivism thus can be only a part of an acceptable theory of justice.

Isolation of myosalvarsan'a

1930 ◽  
Vol 26 (9) ◽  
pp. 942-942
Author(s):  
H. Bauer
Keyword(s):  
Maximum Amount ◽  
The Body ◽  
Drug Excretion ◽  
Clinical Observations ◽  
Short Time ◽  
Detailed Technique ◽  
Cessation Of Treatment

Abstracts. Venereology and Dermatology. Hugo Bauer (D. Z. Bd. 57, H. 4, 29), aiming to study the secretion of myosalvarsan'a, took under observation 4 syphilitics treated with injections of the drug. Excretion of myosalvarsan'a, as well as its absorption, is similar to 'neo' and sulfoxylsalvarsan'y. Most of the arsenobenzol'a introduced into the body is released within a "short time" after injection; four weeks after the cessation of treatment, the body is freed from the maximum amount of introduced As. The author believes that the clinical observations, on the basis of which it is argued that if certain intervals are observed between courses, the cumulative action of As does not occur, are completely fair. The author gives a detailed technique for determining As in selections and supplies the article with visual tables and curves of his own observations.

Determination of albumin content in blood serum based on the results of dynamic surface tension

2021 ◽  
Vol 1 (6) ◽  
pp. 68-73
Author(s):  
M. S. Tsarkova ◽  
◽  
I. V. Milaeva ◽  
S. Yu. Zaytsev ◽  
◽  
...  
Keyword(s):  
Surface Tension ◽  
Blood Serum ◽  
Objective Assessment ◽  
Dynamic Surface Tension ◽  
The Body ◽  
Maximum Pressure ◽  
Dynamic Surface ◽  
Good Convergence ◽  
Albumin Content

The blood test allows you to give an objective assessment of the state of health of animals and timely identify changes occurring in the body. To assess the content of albumins in the blood serum, the method of measuring the dynamic surface tension on the VRA-1P device, which works according to the method of maximum pressure in the bubble, was used. Based on the results of the measurements, a mathematical model was proposed, and using the regression analysis method, formulas for determining the concentration of albumins were developed, which showed good convergence with other measurement methods.

scholarly journals XXVI.—Treatment of Aneurysm by Electrolysis.

1908 ◽  
Vol 28 ◽  
pp. 400-402
Author(s):  
Dawson Turner
Keyword(s):  
Surgical Treatment ◽  
Blood Serum ◽  
The Body ◽  
The Other ◽  
Difficult Question ◽  
Actual Effect

MANY attempts have been made to utilise electrolysis in aneurysms, especially in those thoracic ones that are not amenable to ordinary surgical treatment; it has been hoped that the clotting which occurs around the poles might serve as a nucleus for further coagulation and deposits of fibrin, and that the aneurysm cavity might in this way become partially filled up. Such attempts have not met with much success hitherto, and the purpose of this research has been to endeavour to determine by experiments on blood serum outside the body what the actual effect of electrolysis is so far as regards clotting. Various methods of electrolysing the blood in an aneurysm have been used by surgeons. Ciniselli introduced needles connected with both poles, and reversed the direction of the current every five minutes; of 38 cases so treated, 27 were ameliorated, but none were cured. In the unipolar method one pole only was introduced, and the other was connected with an indifferent pad placed in the vicinity. The difficult question was which pole to introduce. The positive pole gave the firmest clot, but it was thought that it might be difficult to withdraw, and that hæmorrhage or even rupture of the vessel might follow.

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