scholarly journals Femoston 1/5 as a preparation continuous combined hormonotherapy in pre- and postmenopausal patients

2003 ◽  
Vol 52 (2) ◽  
pp. 101-106
Author(s):  
Margarita A. Repina

The paper presents the results of a study of a low-dose drug for continuous HRT - Femoston 1/5. The drug quite effectively eliminates (reduces) psychoemotional and vegetative-vascular symptoms of peri- and postmenopause, eases the course of hypertension, does not affect body weight gain, actually does not cause breakthrough bleeding, growth of myomatous nodes, does not affect the size of the uterus and the thickness of the endometrium (within a year reception). Taking the drug is accompanied by positive dynamics of the level of glycemia, high and low density lipoproteins, the degree of aggregation and intravascular activation of platelets, which improves the state of peripheral blood flow. The presented data allow us to recommend Femoston 1/5 as a means of HRT for postmenopausal and perimenopausal patients with concomitant uterine myoma and endometriosis.

2019 ◽  
Vol 15 (2) ◽  
pp. 140-147
Author(s):  
Magdy M. Ismail ◽  
El-Tahra M. Ammar ◽  
Abd El-Wahab E. Khalil ◽  
Mohamed Z. Eid

Background and Objective: Yoghurt, especially bio-yoghurt has long been recognized as a product with many health benefits for consumers. Also, honey and olive oil have considerable nutritional and health effects. So, the effect of administration of yoghurt made using ABT culture and fortified with honey (2 and 6%), olive oil (1 and 4%) or honey + olive oil (2+1 and 6+4% respectively) on some biological and hematological properties of rats was investigated.Methods:The body weight gain, serum lipid level, blood glucose level, serum creatinine level, Glutamic Oxaloacetic Transaminase (GOT) activity, Glutamic Pyruvic Transaminase (GPT) activity, leukocytes and lymphocytes counts of rats were evaluated.Results:Blending of bio-yoghurt with rats' diet improved body weight gain. Concentrations of Total plasma Cholesterol (TC), High-Density Lipoprotein cholesterol (HDL), Low-Density Lipoprotein cholesterol (LDL), Very Low-Density Lipoprotein cholesterol (VLDL) and Triglycerides (TG) significantly lowered in plasma of rats fed bio-yoghurt. Levels of TC, LDL, VLDL, and TG also decreased in rat groups feed bio-yoghurt supplemented with honey and olive oil. LDL concentrations were reduced by 10.32, 18.51, 34.17, 22.48, 43.30% in plasma of rats fed classic starter yoghurt, ABT yoghurt, ABT yoghurt contained 6% honey, ABT yoghurt contained 4% olive oil and ABT yoghurt contained 6% honey + 4% olive oil respectively. The blood glucose, serum creatinine, GOT and GPT values of rats decreased while white blood cells and lymphocytes counts increased by feeding bioyoghurt contained honey and olive oil.Conclusion:The findings enhanced the multiple therapeutic effects of bio-yoghurt supplemented with honey and olive oil.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ganesha Ade Riemas ◽  
Iman Hernaman ◽  
Diky Ramdani ◽  
Bambang Nurhadi

ABSTRAK. Tujuan penelitian ini untuk mengukur seberapa besar pengaruh minyak ikan yang sudah terenkapsulasi terhadap kolesterol darah dan performa pada Domba. Penelitian telah dilakukan di Sub Unit Pelayanan Pengembangan Pembibitan Ternak Domba dan Kambing (SUPPPTDK) Bunihayu, Subang pada tanggal 20 Januari 2020 sampai 27 Maret 2020. Sebanyak 18 ekor domba Ekor Tipis jantan dengan bobot 15,99±0,98 kg dialokasikan ke dalam 3 perlakuan secara acak. Domba tersebut diberi ransum perlakuan yang disuplementasi dengan mikroenkapsulasi minyak ikan sebanyak 0% (P0), 2,5% (P1), dan 5% (P2). Data yang terkumpul dilakukan analisis ragam dan bila hasil berbeda nyata maka dilanjutkan dengan uji Duncan. Hasil menunjukkan bahwa mikroenkapsulasi minyak ikan dapat menurunkan kolesterol darah (P0,05), namun tidak berpengaruh nyata terhadap pertambahan bobot badan, konsumsi dan konversi ransum (P0,05). Penurunan kadar kolesterol terjadi pada kelompok domba dengan perlakuan mikroenkapsulasi sebanyak 2,5% (P1) dan mikroenkapsulasi 5% (P2). Kadar kolesterol darah masing-masing perlakuan berturut-turut adalah 100,70 mg/dl (P0); 96,20 mg/dl (P1); dan 78,76 mg/dl (P2). Rataan yang terbaik pada pertambahan bobot badan, konsumsi bahan kering harian, dan konversi ransum terdapat pada P2 yaitu 63,96 g/hari, 574,13 g/hari, dan 9,08. Hasil penelitian dapat disimpulkan bahwa mikroenkapsulasi minyak ikan dapat menurunkan kolesterol darah, dengan penurunan tertinggi pada pemberian 5%.  (The impact of microencapsulation fish oil in feed on blood cholesterols and performance on sheep) ABSTRAK. This study measured the effect of encapsulated fish oil on blood cholesterol and sheep performance. The study was conducted at the Bunihayu Sheep and Goat Breeding Services Bunihayu, Subang on January 20, 2020 to March 27, 2020. A total of 18 male thin-tailed sheep 15.99±0.98 kg were allocated randomly into 3 treatments. The sheep were given feed supplemented with fish oil microencapsulation of 0% (P0), 2.5% (P1), and 5% (P2). The data were collected and analyzed by analysis of variance and, if the result is significantly different, continued by Duncan's test. The results showed that fish oil microencapsulation decreased blood cholesterol levels (P0.05). However, it did not affect body weight gain, consumption, and feed conversion (P0.05). Decreased levels of cholesterol occurred in the group of sheep with 2.5% microencapsulation (P1) and 5% microencapsulation (P2). Blood cholesterol levels of each treatment were 100.70 mg/dl (P0); 96.20 mg/dl (P1); and 78.76 mg/dl (P2), respectively. Averagely, the highest body weight gain, dry matter intake and feed conversion were found in P2 as much as 63.96 g/day, 574.13 g/day, and 9.08, respectively. The results can be concluded that microencapsulation of fish oil can reduce blood cholesterol, with the highest decrease at the level of 5%.


2017 ◽  
Vol 10 (2) ◽  
pp. 64
Author(s):  
Martha Kayadoe ◽  
O R Faidiban ◽  
Purwaningsih Purwaningsih ◽  
Dwi Nurhidayati

<p>The objective of this study was to investigate the performances of rabbit using several levels of Kebar grass in concentrate, i.e. 0, 5, 10 and 15%, according to protein requirement 19%. Research designed by using Randomized Design Group and each treatment was replicated two times. Data were analyzed using Analysis of Variance and Continued with LSD test. The addition of kebar grass concentrates had no effect in ration and feed efficiency, but significantly affect body weight gain in treatment of 10% and 15% compared to without addition (0%) of kebar grass and 5%. The addition of kebar grass did not affect palatability.</p><p>Key words : kebar grass, rabbit, concentrate, formulations</p>


2017 ◽  
Vol 10 (2) ◽  
pp. 64
Author(s):  
Martha Kayadoe ◽  
O R Faidiban ◽  
Purwaningsih Purwaningsih ◽  
Dwi Nurhidayati

<p>The objective of this study was to investigate the performances of rabbit using several levels of Kebar grass in concentrate, i.e. 0, 5, 10 and 15%, according to protein requirement 19%. Research designed by using Randomized Design Group and each treatment was replicated two times. Data were analyzed using Analysis of Variance and Continued with LSD test. The addition of kebar grass concentrates had no effect in ration and feed efficiency, but significantly affect body weight gain in treatment of 10% and 15% compared to without addition (0%) of kebar grass and 5%. The addition of kebar grass did not affect palatability.</p><p>Key words : kebar grass, rabbit, concentrate, formulations</p>


2013 ◽  
Vol 4 (4) ◽  
pp. 226-232 ◽  
Author(s):  
Hiroki Kumagai ◽  
Naoto Kubota ◽  
Tetsuya Kubota ◽  
Takehiro Takahashi ◽  
Mariko Inoue ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 408 ◽  
Author(s):  
Miguel Z Martín-González ◽  
Héctor Palacios ◽  
Miguel A Rodríguez ◽  
Lluís Arola ◽  
Gerard Aragonès ◽  
...  

Conjugated linoleic acid (CLA) is a dietary supplement that has been shown to improve obesity. However, some authors have associated high doses of CLA supplementation with liver impairment and insulin resistance. The aim of this study was to assess whether the consumption of low doses of CLA maintained the beneficial effects on the main metabolic disturbances associated with metabolic syndrome (MetS) but prevented the occurrence of non-desirable outcomes associated with its consumption. Male Wistar rats, fed standard or cafeteria (CAF) diet for 12 weeks, were supplemented with three different low doses of CLA in the last three weeks. Both biochemical and H1 NMR-based metabolomics profiles were analysed in serum and liver. The consumption of 100 mg/kg CLA, but not doses of 200 and 300 mg/kg, ameliorated the increase in body weight gain as well as the serum concentrations of glucose, insulin, cholesterol, triglyceride, diglyceride, and total phospholipid induced by a CAF diet. In turn, CLA reverted the increase in lactate, alanine, and glucose concentrations in the liver of these animals, but enhanced hepatic cholesterol accumulation without any detrimental effect on liver function. In conclusion, a low dose of CLA corrected the adverse effects associated with MetS without compromising other metabolic parameters.


2012 ◽  
Vol 108 (12) ◽  
pp. 2166-2175 ◽  
Author(s):  
Su-Jung Cho ◽  
Un Ju Jung ◽  
Myung-Sook Choi

Consumption of a high-fat diet (HFD) enriched in saturated fat induces excessive weight gain due to adiposity, which can lead to metabolic complications, as well as increased risk of fatty liver disease and CVD. The present study investigated the underlying mechanism and dose–response effects of resveratrol (RV) on obesity, hepatic steatosis and dyslipidaemia in mice fed a HFD. Male C57BL/6J mice were fed a normal diet or a HFD (20 % fat, w/w) combined with 0·005 or 0·02 % (w/w) RV for 10 weeks. As expected, mice fed a HFD developed obesity, as shown by increased body weight gain, visceral fat, hepatic fat and plasma cholesterol. RV significantly reduced visceral fat and plasma NEFA. In the liver of HFD-fed mice, RV significantly reduced TAG and cholesterol, as well as lipid droplet number and size. A low dose of RV (0·005 %) appeared to be more effective than a higher dose of RV (0·02 %) for suppressing adiposity and hepatic steatosis development with a significant decrease in body weight gain, plasma TAG and total cholesterol levels. These changes were seemingly attributable to a suppression of the fatty acid (FA) synthase, glucose-6-phosphate dehydrogenase, and phosphatidate phosphohydrolase and/or an activation of FA oxidation in the liver and epididymal adipose tissue. In conclusion, daily consumption of a low dose of RV is effective for protecting against diet-induced obesity, hepatic steatosis and dyslipidaemia in HFD-fed mice.


2021 ◽  
Vol 5 (1) ◽  
pp. 31-36
Author(s):  
Syifa Nurjannah ◽  
Ikhsan Kholiq ◽  
Tedi Akhdiat ◽  
Nilawati Widjaya

The purpose of this research was to determine field grass substitution by hay African Star Grass (Cynodon plectostachyus) on the productivity of local male rabbits with an age of 3 months old. The research was conducted in October-November 2020 in Central Pojok Village, Cikahuripan, Lembang, West Bandung Regency. The research method used a completely randomized design with five treatments which were P0: 80% field grass + 20% concentrate; P1: 60% field grass + 20% hay African Star Grass + 20% concentrate; P2: 40% field grass + 40% hay African Star Grass + 20% concentrate; P3: 20% field grass + 60% hay African Star Grass + 20% concentrate; P4: 80% African Star Grass hay + 20% concentrate, and each treatment was repeated five times so that the number of rabbits used were 25 heads. Data obtained were analyzed using SPSS software and Duncan's multiple range test. The results showed that the substitution of field grass by Afrikan Star Grass affected ration consumption (P<0.05) with an average of 150.79-185.78 grams/head/day, but did not affect body weight gain and feed conversion (P>0.05) with an average of 14.64-19.78 grams/head/day and 7.94-11.60, respectively. This study concluded that the provision of hay African Star Grass at the level of 20% showed more optimal results.


1968 ◽  
Vol 8 (33) ◽  
pp. 405
Author(s):  
P McInnes ◽  
BC Roberts ◽  
PM Finlayson ◽  
JV Russel

Summary-The response to supplementary feeding of weaners was studied at Condobolin, New South Wales. Three equal groups of 120, 3-4-month-old Merino weaners were rotated every six weeks for 18 weeks in a three-paddock system. The pasture consisted mainly of relatively dry heliotrope (Heliotropitlm europaetm) but there was some green fodder provided by other pasture species. Unsupplemented weaners gained 54 g per day and a group supplemented with unrestricted amounts of a hammerrnilled mixture of three parts chopped lucerne hay and one part oat grain gained an additional 7 g per day (P<0.05). The mean greasy fleece growth of the supplemented group (2.86 kg) between birth and approximately 10 months of age was greater than the unsupplemented group (2.68 kg, P*lt;0.05). The cost of the supplement would appear to be greater than the increased returns. Weaners allowed unrestricted access to a mineral feeding block gained a mean weight of 42 g per day which was significantly less than the unsupplemented group (P<0.05) and failed to maintain weight during the last six weeks of the trial. Selenium and cobalt treatments, which were given to some sheep in all groups, did not affect body weight gain or wool production.


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