scholarly journals Differential ultrasound diagnostics of the changes of endometrium atthe women of reproductive age

2004 ◽  
Vol 53 (2) ◽  
pp. 36-40
Author(s):  
Lidia E. Sharova ◽  
Marina M. Safronova
Keyword(s):  
Menstrual Cycle ◽  
Russian Patent ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ultrasound Diagnostics

In article outcomes of a research of 294 women with clinical displays of infringement menstrual cycle, shown developing as disfunctional changes in endometrium, resemble reminding polyps are submitted. For specification of character of a pathology is used the functional farmakodinamic oxytocin test (the Russian patent for the invention № 2126653). After statement of the diagnosis and assignment corresponding therapy during 36 months, restoration ultrasonography picture of endometrium was observed according to a phase of menstrual cycle.

scholarly journals Possible impact of variations in some Cytokine levels during menstrual cycle in women of reproductive age infected with Pulmonary Tuberculosis at Nnewi, Nigeria'

2018 ◽  
Vol 08 (02) ◽  
Author(s):  
Nkiruka Rose Ukibe ◽  
Solomon Nwabueze Ukibe ◽  
Emmanuel Ikechukwu Onwubuya ◽  
Chinedum Charles Onyenekwe ◽  
Ifeoma Nwamaka Monago ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Pulmonary Tuberculosis ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Cytokine Levels

scholarly journals Plasma Volume, Hydration and Nutritional Biomarker Concentrations Across the Menstrual Cycle (P24-052-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Sixtus Aguree ◽  
Hilary Bethancourt ◽  
Leigh Taylor ◽  
Asher Yoel Rosinger ◽  
Lacy M Alexander ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Plasma Volume ◽  
Plasma Osmolality ◽  
Reproductive Age ◽  
Magnesium Concentration ◽  
Women Of Reproductive Age ◽  
Blood Draw ◽  
Healthy Women ◽  
Markers Of Inflammation ◽  
Concentration Changes

Abstract Objectives To examine changes in plasma volume, hydration, and micronutrient concentrations across the menstrual cycle among healthy women of reproductive age. Methods Healthy women aged 18 to 44 years were studied longitudinally across a single menstrual cycle (n = 35). Women made three visits (v1, v2, and v3) to the study center around cycle days 2, 12 and 21 (adjusted for individual cycle length) representing early follicular, late follicular and midluteal phases, respectively. At each visit, blood samples were collected before and after injection of indocyanine green (ICG). ICG in plasma was measured with a spectrophotometer within 2 hours of blood draw, to estimate plasma volume. Urine specific gravity (USG) was measured with a hand-held refractometer; urine and plasma osmolality were measured using freezing point depression osmometry. Serum ferritin was measured by ELISA; serum concentrations for 5 minerals were measured by inductively coupled plasma mass spectrometry. A mixed-effects model was used to examine changes in plasma volume and biomarker concentrations across the menstrual cycle; plasma volume and biomarker associations were tested with Spearman's correlation. Results Participants had a mean (SD) BMI of 21.6 (1.9) kg/m2. Plasma volume showed a non-significant decrease of 122 mL from v1 to v2 (P = 0.165; Table 1) and remained stable from v2 to v3 (P = 0.900). However, plasma osmolality decreased throughout the cycle from v1 to v3 (P < 0.001). Urine osmolality fell slightly from v1 to v2 (P = 0.214) followed by a significant rise from v2 to v3 (P = 0.026) but USG was constant across the cycle. From v1 to v3, serum magnesium concentration declined by 4.5% (P = 0.001); zinc had a similar decline that did not reach statistical significance (P = 0.057). Mean copper, calcium, manganese, ferritin, and hemoglobin concentrations did not change across the cycle (all P > 0.05). Adjusting for markers of inflammation (α1-acid glycoprotein and C-reactive protein) and plasma volume did not affect biomarker concentration changes. Plasma volume was not correlated with nutritional biomarkers at any timepoint (all P > 0.05, Table 2). Conclusions Concentrations of micronutrients were not related to plasma volume. Some hydration and micronutrient biomarkers changed across the menstrual cycle, which could have implications for the timing of measurements in women of reproductive age. Funding Sources The Pennsylvania State University. Supporting Tables, Images and/or Graphs

scholarly journals Menstrual cycle and gynecologic pathology in menstrual-related migraine

2021 ◽  
Vol 13 (4) ◽  
pp. 12-17
Author(s):  
E. A. Kiryanova ◽  
G. R. Tabeeva
Keyword(s):  
Menstrual Cycle ◽  
Cycle Length ◽  
Hormonal Contraception ◽  
Reproductive Age ◽  
Patient Evaluation ◽  
Women Of Reproductive Age ◽  
Endometrial Polyps ◽  
Leading Role ◽  
Prospective Comparative Study ◽  
Group 2

Migraine is the first most frequent cause of disability among women of reproductive age globally, and up to 60% of patients note the association of headache attacks with menstruation.Objective: to determine the features of menstrual cycle and gynecologic pathology in women with menstrual-related migraine (MRM).Patients and methods. A prospective comparative study included 69 women of reproductive age with a migraine diagnosis who did not receive hormonal contraception. Depending on the association of migraine attacks with menstruation (according to headache diaries), the patients were divided into two groups: the 1st group consisted of 44 patients with MRM; group 2 — 25 patients with non-menstrual migraine (without the association of attacks with menstruation).Results and discussion. Patients with MRM had heavier menstrual bleeding, longer menstruations (more than six days), abnormal menstrual cycle length and regularity, dysmenorrhea. In addition, the obtained data indicate a comorbid estrogen-associated gynecological pathology (endometriosis, adenomyosis, endometrial polyps, myoma) in MRM.Conclusion. Presumably, the hypothalamic-pituitary-ovarian axis dysfunction plays the leading role in the MRM. It presents with menstrual cycle abnormalities and increased presence of estrogen-associated gynecological pathology, which should be considered during patient evaluation and suggesting recommendations.

scholarly journals Clinical features of polycystic ovary syndrome phenotypes in women with normogonadotropic anovulation in reproductive age

2019 ◽  
Vol 68 (3) ◽  
pp. 7-14
Author(s):  
Elena I. Abashova ◽  
Maria A. Shalina ◽  
Elena V. Misharina ◽  
Natalia N. Tkachenko ◽  
Olga L. Bulgakova
Keyword(s):  
Menstrual Cycle ◽  
Polycystic Ovary Syndrome ◽  
Carbohydrate Metabolism ◽  
Clinical Features ◽  
Endometrial Hyperplasia ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Chronic Endometritis

Hypothesis/aims of study. Polycystic ovary syndrome (PCOS) is a common disease, the frequency of which ranges from 8 to 13% in women of reproductive age. PCOS is a complex polygenic endocrine disorder with reproductive, metabolic, and psychological features. Currently, four PCOS phenotypes are identified that are associated with metabolic disorders, insulin resistance, impaired glucose tolerance (IGT), diabetes mellitus, and an increase in the number of risk factors for cardiovascular diseases. The aim of this study was to investigate the clinical features of PCOS phenotypes in women with normogonadotropic anovulation in reproductive age. Study design, materials, and methods. The study included 60 women of reproductive age from 24 to 37 years (mean age 28 ± 4 years) with PCOS and normogogonadotropic, normoprolactinemic anovulation. We studied the levels of anti-mullerian, follicle-stimulating, luteinizing hormone, prolactin, estradiol, and androgens from days 2 to 5 of the menstrual cycle. The serum progesterone level was studied by ELISA using test systems manufactured by Alkor Bio Ltd. (Russia) on days 20–23 of the menstrual cycle for three consecutive cycles. The average level of progesterone in the blood on days 20–23 of the menstrual cycle was 3.1 ± 1.5 nM. Echographic methods for diagnosing polycystic ovaries were used. All women included in the study underwent hysteroscopy on days 18–22 of the menstrual cycle, followed by a histological and immunohistochemical study of the endometrium. Results. In women with anovulatory PCOS phenotypes, phenotype A (classical) was detected in 32 (53.3%) women; phenotype B (anovulatory) in 18 (30%) women; phenotype D (non-androgenic) in 10 (16.7%) women with. In 32 (53.3%) patients, changes in carbohydrate metabolism (IGT) were found. Clinical and biochemical manifestations of androgen-dependent dermopathy (acne, oily seborrhea, and hirsutism) were significantly (p < 0.05) more often observed in PCOS patients with phenotypes A (84.4%) and B (88.9%) than in women with phenotype D (30%). In the majority (93.8%) of patients with IGT, the androgenic-anovulatory PCOS phenotypes were detected: phenotype A in 20 (62.5%) women and phenotype B in 10 (31.3%) women. Phenotype D (non-androgenic) was present only in two women with PCOS and IGT. As a result of complex histological and immunohistochemical studies of endometrial biopsy specimens, chronic endometritis was detected in 44 (73.3%) examined women with PCOS and simple glandular endometrial hyperplasia was diagnosed in 13 (21.7%) PCOS patients. The incidence of chronic endometritis and simple glandular endometrial hyperplasia in women with normogonadotropic anovulation and PCOS directly depended (r = 0.35; p < 0.05) on disorders of carbohydrate metabolism and was detected more often in patients with PCOS and IGT. Conclusion. The differential approach to the examination of patients with various PCOS phenotypes allows personalizing the therapy of this disease and determining the complex of preventive measures to improve the quality of life of women of reproductive age.

scholarly journals The scent of attractiveness: levels of reproductive hormones explain individual differences in women's body odour

2018 ◽  
Vol 285 (1886) ◽  
pp. 20181520 ◽  
Author(s):  
Janek S. Lobmaier ◽  
Urs Fischbacher ◽  
Urs Wirthmüller ◽  
Daria Knoch
Keyword(s):  
Individual Differences ◽  
Menstrual Cycle ◽  
Mate Choice ◽  
Reproductive Fitness ◽  
Reproductive Hormones ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Hormone Levels ◽  
Body Odour ◽  
Cortisol Levels

Individuals are thought to have their own distinctive body odour which reportedly plays an important role in mate choice. In the present study we investigated individual differences in body odours of women and examined whether some women generally smell more attractive than others or whether odour preferences are a matter of individual taste. We then explored whether levels of reproductive hormones explain women's body odour attractiveness, to test the idea that body odour attractiveness may act as a chemosensory marker of reproductive fitness. Fifty-seven men rated body odours of 28 healthy, naturally cycling women of reproductive age. We collected all odours at peak fertility to control for menstrual cycle effects on body odour attractiveness. Women's salivary oestradiol, progesterone, testosterone and cortisol levels were assessed at the time of odour collection to test whether hormone levels explain body odour attractiveness. We found that the men highly agreed on how attractive they found women's body odours. Interestingly, women's body odour attractiveness was predicted by their oestradiol and progesterone levels: the higher a woman's levels of oestradiol and the lower her levels of progesterone, the more attractive her body odour was rated. In showing that women's body odour attractiveness is explained by levels of female reproductive hormones, but not by levels of cortisol or testosterone, we provide evidence that body odour acts as a valid cue to potential fertility.

scholarly journals Modern approaches to the diagnosis of malignant trophoblastic tumors

2021 ◽  
Vol 23 (2) ◽  
pp. 345-348
Author(s):  
Siusan N. Mamedli ◽  
Marina A. Chekalova ◽  
Liudmila A. Meshcheriakova
Keyword(s):  
Ultrasound Examination ◽  
Reproductive Age ◽  
Tumor Resistance ◽  
Women Of Reproductive Age ◽  
Pelvic Organs ◽  
National Medical ◽  
Ultrasound Diagnostics ◽  
Trophoblastic Tumors ◽  
Unique Experience ◽  
Onset Of Remission

Malignant trophoblastic tumors (TO) include invasive and metastatic cystic drift, choriocarcinoma, TO of the placental bed, and epithelioid TO. They are rare, mainly in women of reproductive age, and most importantly, they are always associated with pregnancy. To date, the Blokhin National Medical Research Center of Oncology has accumulated a large and unique experience of modern diagnostics and treatment of patients with various forms of malignant TO. An obligatory stage of the examination is ultrasound diagnostics of the pelvic organs. In addition, performing an ultrasound examination during the treatment period, along with monitoring the level of chorionic gonadotropin, makes it possible to assess the effectiveness of treatment, diagnose tumor resistance and ascertain the onset of remission.

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