scholarly journals М.Е. Lobashev and The New Chapters in the Science - Biology, Physiology and Genetics of Conditioned Reflex

2007 ◽  
Vol 5 (4) ◽  
pp. 5-10
Author(s):  
Nina G Lopatina

This article covers the ten-year period (1949-1959) of M.E. Lobashev work in the Pavlov Institute of Physiology. During this time he realized his ideas about biological adaptive role of conditioned reflex. According to Lobashev, conditioned reflex is the universal mechanism of interaction between the organism and environment, regulating the realization of genetic information, promoting active adaptation to habitat in ontogenesis and providing the functional continuity between generations ("signal inheritance").

2018 ◽  
Vol 54 (6) ◽  
pp. 78-93
Author(s):  
V. V. Grubinko ◽  
O. I. Bodnar ◽  
A. I. Lutsiv ◽  
G. B. Viniarska
Keyword(s):  

2020 ◽  
Vol 63 (2) ◽  
pp. 46-62
Author(s):  
Suren T. Zolyan

We discuss the role of linguistic metaphors as a cognitive frame for the understanding of genetic information processing. The essential similarity between language and genetic information processing has been recognized since the very beginning, and many prominent scholars have noted the possibility of considering genes and genomes as texts or languages. Most of the core terms in molecular biology are based on linguistic metaphors. The processing of genetic information is understood as some operations on text – writing, reading and editing and their specification (encoding/decoding, proofreading, transcription, translation, reading frame). The concept of gene reading can be traced from the archaic idea of the equation of Life and Nature with the Book. Thus, the genetics itself can be metaphorically represented as some operations on text (deciphering, understanding, code-breaking, transcribing, editing, etc.), which are performed by scientists. At the same time linguistic metaphors portrayed gene entities also as having the ability of reading. In the case of such “bio-reading” some essential features similar to the processes of human reading can be revealed: this is an ability to identify the biochemical sequences based on their function in an abstract system and distinguish between type and its contextual tokens of the same type. Metaphors seem to be an effective instrument for representation, as they make possible a two-dimensional description: biochemical by its experimental empirical results and textual based on the cognitive models of comprehension. In addition to their heuristic value, linguistic metaphors are based on the essential characteristics of genetic information derived from its dual nature: biochemical by its substance, textual (or quasi-textual) by its formal organization. It can be concluded that linguistic metaphors denoting biochemical objects and processes seem to be a method of description and explanation of these heterogeneous properties.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 39-39
Author(s):  
Mark McCully

Abstract The role of the breed association has historically been to keep a registry of a pure breed, aggregate the performance data surrounding that one breed, develop breeding and selection tools, and conduct breed promotion. Larger associations have been able to augment that with operating magazines and other media, running branded beef programs, feeder calf marketing programs, and genetic evaluation for other breeds. The relevance of breed associations is being and will continue to be challenged as genomics and large commercial databases develop and allow for breeding and selection tools to be developed independently by large breeders or private entities. Gene editing and other such technology will also challenge the traditional seedstock models and opens the door for proprietary genetic lines. Breed associations may need to modify their traditional policies to incorporate these innovations. Supply chains will continue to become far more sophisticated and will incorporate more genetic information to guide management decisions and potentially validate brand promises around sustainability. To stay relevant, breed associations of the future will need to do the following: Balance the needs of diverse membership (show, hobby, lifestyle, etc.) with commercial industry value and significance. Have access to large amounts of data and be leaders in adopting the most current technologies. Deliver tools for breeders that enhance the profitability of commercial producers – identify optimum production levels vs maximum outputs. Work collaboratively with multiple supply chains providing the needed genetic information. Be a significant educational resource to breeders and commercial producers. Be a leader in research on breed improvement and genetic advancement. Have value-added programs that create real and sustained pull-through demand for the end product.


2006 ◽  
Vol 38 (3) ◽  
pp. 219-224 ◽  
Author(s):  
Sivia Barnoy ◽  
Dorit Appel ◽  
Chava Peretz ◽  
Hana Meiraz ◽  
Mally Ehrenfeld

Lex Russica ◽  
2019 ◽  
pp. 121-128 ◽  
Author(s):  
M. N. Maleina

The use of modern genomic technologies, along with the benefits to the man and society, can lead to negative consequences. Such risks exist both in the process and after the production, isolation, modification, storage of DNA. Prior to detailed legislative regulation of relations regarding the use of genomic technologies for medicinal purposes and not for medical reasons, legal principles become vital.The paper formulates the following basic legal principles of genomic technologies application: the principle of preventive actions of the state to protect citizens from the risks of using genomic technologies; the principle of preserving the human genome as a special species; the principle of guaranteeing the inviolability of the individual of every citizen when using genomic technologies; the principle of priority of life and health of citizens over the interests of science and society; the principle of equality of citizens regardless of genetic characteristics; the principle of protection of genetic information of every citizen as part of personal data; the principle of guaranteeing access to the citizen’s own genetic information. Legal principles can be used to resolve a dispute by analogy of law.


2019 ◽  
Author(s):  
Benjamin Oosterhoff

This study examined associations among adolescent risk preference and political engagement using nationally representative Monitoring the Future data from high school seniors (N=109,574; modal age=18 years) spanning 1976-2014. Greater risk preference was associated with greater past voting, donating to a campaign, writing government officials, boycotting, and protesting. Greater risk preference was associated with higher future intentions to boycott and protest, but lower intentions to donate to or volunteer for a campaign. In general, associations between risk preference and political engagement became stronger with higher levels of political interest. Results highlight the importance of considering the adaptive role of adolescent risk preference and suggest that political engagement may be a constructive outlet for youth who pursue or are comfortable taking risks.


Author(s):  
A. V. Shashkova ◽  
A. A. Goryaev ◽  
N. I. Smirnova

Presented is the review of literature data on the recently discovered system of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), which takes part in the defense against penetration of alien genetic information in prokaryotes. CRISPR structural peculiarities and functions, and putative mechanism of action are described. Also presented are data on the availability of this system in particularly dangerous infections agents and on the possibility of its application for molecular typing.


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