scholarly journals Fulminant Guillain-Barré Syndrome (GBS) with a Constellation of Uncommon Clinical Manifestations: Differential Diagnosis and Treatment Challenges

2019 ◽  
pp. 157-161
Author(s):  
Youssef Ghosn ◽  
Mohammed Hussein Kamareddine ◽  
Hilal Abdessamad ◽  
Tarek Safi ◽  
Carmen Adem ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain-Barré Syndrome

2019 ◽  
pp. 193-207
Author(s):  
Matthew J. G. Burford ◽  
Richard A. Lewis
Keyword(s):  
Differential Diagnosis ◽  
Immune Therapy ◽  
Treatment Options ◽  
General Pattern ◽  
Clinical Manifestations ◽  
Sudden Onset ◽  
Guillain Barre Syndrome ◽  
Clinical Scenario ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

This chapter begins by outlining the origin of Guillain-Barré syndrome (GBS). It looks at the epidemiology and antecedent events. It also considers clinical manifestations. The classic clinical scenario is one of acute, symmetric, progressive, ascending weakness, and areflexia, with or without sensory symptoms days to weeks after a preceding infection. Next differential diagnosis is examined. The differential diagnosis of GBS is quite broad and includes disorders leading to sudden onset of weakness. The general pattern of clinical involvement and medical history helps to hone the differential. Finally, the chapter looks at management of the syndrome and treatment options for various different groups, such as immune therapy.

scholarly journals Co-Occurrence of Guillain-Barre Syndrome and Multiple Sclerosis: A Rare Case Report

2021 ◽  
pp. 1-5
Author(s):  
Amr Hassan ◽  
Alaa El-Mazny ◽  
Mohammed Saher ◽  
Ismail Ibrahim Ismail ◽  
Mohammed Almuqbil
Keyword(s):  
Multiple Sclerosis ◽  
Differential Diagnosis ◽  
Case Report ◽  
Rare Case ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Rare Case Report ◽  
Central Nervous Systems ◽  
Guillain Barré ◽  
Demyelinating Disorders

Guillain-Barre syndrome (GBS) and multiple sclerosis (MS) are autoimmune demyelinating disorders of the peripheral and central nervous systems, respectively. The co-occurrence of these 2 conditions is rare in the literature. Herein, we present a rare case of GBS and MS in a 19-year-old female who presented initially with GBS followed by MS, and we provide a literature review. Despite being rare, it should be kept in mind in the differential diagnosis of patients with atypical and usual presentation of both diseases.

OVERLAP NEUROLOGICAL SYNDROMES ASSOCIATED WITH ANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE: CLINICAL OBSERVATION

2021 ◽  
Vol 100 (2) ◽  
pp. 284-287
Author(s):  
E.S. Druzhinina ◽  
◽  
R.T. Bembeeva ◽  
D.S. Druzhinin ◽  
U.M. Azizova ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Clinical Observation ◽  
Clinical Manifestations ◽  
Overlap Syndrome ◽  
Guillain Barre Syndrome ◽  
Acid Decarboxylase ◽  
Pediatric Practice ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

The article presents a description of an overlap syndrome, rare in pediatric practice, associated with antibodies to glutamic acid decarboxylase in a 4-year-old child, which was initially regarded as a variant of Guillain–Barré syndrome due to the similarity of clinical manifestations.

scholarly journals Atypical Lyme Neuroborreliosis, Guillain-Barré Syndrome or Conversion Disorder: Differential Diagnosis of Unusual Neurological Presentations

2019 ◽  
Vol 11 (1) ◽  
pp. 142-147
Author(s):  
Tomás Teodoro ◽  
Renato Oliveira ◽  
Pedro Afonso
Keyword(s):  
Differential Diagnosis ◽  
Conversion Disorder ◽  
Skin Lesions ◽  
Response To Therapy ◽  
Guillain Barre Syndrome ◽  
Functional Improvement ◽  
Test Results ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Typical Skin

Nervous system Lyme disease and Guillain-Barré syndrome are common neurological conditions that may present with unusual symptoms rendering differential diagnosis difficult. We report the case of a 62-year-old woman presenting with asymmetrical tetraparesis and hyporeflexia. Initially the presumed diagnosis of Guillain-Barré syndrome with a possible functional component was suspected and treatment with intravenous immunoglobulin was initiated. Due to partial response to therapy and further test results including positive serologies and cerebrospinal fluid antibodies for Borrelia, the diagnosis of neuroborreliosis was considered. Further exploring revealed the possibility of exposure to ticks although there was no report of typical skin lesions. Daily physical therapy and appropriate antibiotic treatment with parenteral ceftriaxone resulted in significant improvement of motor symptoms and functional status. The patient was discharged with marked functional improvement and indication for further physical rehabilitation.

scholarly journals A Multicentric Prospective Incidence Study of Guillain-Barré Syndrome in Italy. The ITANG Study

2015 ◽  
Vol 45 (2) ◽  
pp. 90-99 ◽  
Author(s):  
Maria Donata Benedetti ◽  
Maura Pugliatti ◽  
Roberto D''Alessandro ◽  
Ettore Beghi ◽  
Adriano Chiò ◽  
...  
Keyword(s):  
Influenza Vaccination ◽  
Rate Ratio ◽  
Telephone Survey ◽  
Clinical Manifestations ◽  
Guillain Barre Syndrome ◽  
Annual Incidence Rate ◽  
Italian Studies ◽  
Italian Regions ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Background: To assess Guillain-Barré syndrome (GBS) incidence we relied on the Italian Network for the study of GBS (ITANG) established in 2010 in 7 Italian regions to analyse the association between influenza vaccination and GBS. Methods: All individuals aged ≥18 years, presenting with clinical manifestations that suggested GBS according to the universally accepted Asbury's diagnostic criteria (1990) were prospectively notified to a centralised database by ITANG neurologists over the period October 1, 2010-September 30, 2011. Through a telephone survey, 9 trained interviewers followed up the cases to diagnosis and then for 1 year since hospital discharge. Validation of case reporting was performed with the support of administrative data in 5 regions. Results: We found 365 cases fulfilling the definition for GBS or one of its variants over 19,846,068 population ≥18 years of age, yielding an annual incidence rate of 1.84 per 100,000 (95% CI 1.65-2.03), 2.30 (95% CI 1.99-2.60) in men and 1.41 (95% CI 1.18-1.64) in women. A highly significant peak of incidence was observed in February 2011 as compared to reference month (September 2011, rate ratio 3.3:1, p < 0.01). Conclusions: In Italy, GBS incidence was among the highest reported in Europe and higher than previously observed in Italian studies.

Sign in / Sign up

Export Citation Format

Share Document