scholarly journals IgA Nephropathy Precedes the Onset of the Rheumatic Disease in a Female with Ankylosing Spondylitis

2017 ◽  
Vol 1 (1) ◽  
pp. 020-022
Author(s):  
HM Al Attia ◽  
MR Carballo
Keyword(s):  
Ankylosing Spondylitis ◽  
Rheumatic Disease ◽  
Iga Nephropathy

scholarly journals SAT0589 RISK FOR PSYCHIATRIC HOSPITALIZATION FOLLOWING A RHEUMA-RELATED HOSPITALIZATION: RESULTS FROM A CZECH NATIONWIDE, COHORT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1253.2-1254
Author(s):  
T. Formánek ◽  
K. Mladá ◽  
M. Husakova
Keyword(s):  
Rheumatoid Arthritis ◽  
Cohort Study ◽  
Ankylosing Spondylitis ◽  
Rheumatic Disease ◽  
Rheumatic Diseases ◽  
Psychiatric Hospitalization ◽  
Population Based ◽  
Index Hospitalization ◽  
Increased Risk ◽  
History Of

Background:Cohort studies using nationwide health registers have shown an increased risk for affective and anxiety disorders in people with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) (1-3). Moreover, a nationwide cohort study demonstrated an increased risk for mental disorders in people with rheumatic diseases (4).Objectives:We aimed to investigate the risk for psychiatric hospitalization following a hospitalization for rheumatic disease.Methods:Using data from the Czech nationwide register of all-cause hospitalizations, we obtained 4 971 individuals hospitalized (index hospitalization) between 2004 and 2012 for rheumatic diseases - RA, spondyloarthritis (including AS, psoriatic arthritis and undifferentiated spondyloarthritis), systemic lupus erythematosus and systemic sclerodermia, with no history of psychiatric and rheuma-related hospitalization in the previous 10 years from the index hospitalization. On these individuals, we randomly matched (on age, gender and year of index hospitalization) controls that were hospitalized in the same time period for a non-rheumatic disease and have no history of psychiatric and rheumatic hospitalization in the last 10 years from their index hospitalization, in the ratio of 1:5. We employed conditional logistic regression for assessing the risk for psychiatric hospitalization in the subsequent 3 years from the index hospitalization. To strengthen our results, we repeated the matching step 100 times and run the analysis on each resulting dataset separately, and pooled the results. The findings are expressed as odds ratios (OR) with 95% confidence intervals (95% CI).Results:We identified an elevated risk for psychiatric (OR = 1.34, 95% CI = 1; 1.78) and for affective disorders (OR = 2.19, 95% CI = 1.17; 4.1) in people hospitalized for rheumatic diseases. We did not find a statistically significant association with organic, psychotic and anxiety disorders.Conclusion:There is an increased risk for experiencing a psychiatric disorder in the period of 3 years after a rheuma-related hospitalization.References:[1]Shen C-C, Hu L-Y, Yang AC, Kuo BI-T, Chiang Y-Y, Tsai S-J. Risk of Psychiatric Disorders following Ankylosing Spondylitis: A Nationwide Population-based Retrospective Cohort Study. The Journal of Rheumatology. 2016;43(3).[2]Park J-S, Jang H-D, Hong J-Y, Park Y-S, Han K, Suh S-W, et al. Impact of ankylosing spondylitis on depression: a nationwide cohort study. Scientific Reports. 2019;9(1):6736.[3]Hsu C-C, Chen S-C, Liu C-J, Lu T, Shen C-C, Hu Y-W, et al. Rheumatoid Arthritis and the Risk of Bipolar Disorder: A Nationwide Population-Based Study. PLOS ONE. 2014;9(9).[4]Sundquist K, Li X, Hemminki K, Sundquist J. Subsequent Risk of Hospitalization for Neuropsychiatric Disorders in Patients With Rheumatic Diseases: A Nationwide Study From Sweden. Archives of General Psychiatry. 2008;65(5):501-7.Acknowledgments:Supported by the project (Ministry of Health Czech Republic) for conceptual development of research organization 00023728 (Institute of Rheumatology).Disclosure of Interests:Tomáš Formánek: None declared, Karolina Mladá: None declared, Marketa Husakova Speakers bureau: Novartis

Absence of IgA nephropathy in patients with ankylosing spondylitis

1986 ◽  
Vol 6 (4) ◽  
pp. 145-149 ◽  
Author(s):  
A. J. G. Swaak ◽  
I. Frankfort ◽  
R. S. Menon ◽  
J. M. Pekelharing ◽  
O. Planten
Keyword(s):  
Ankylosing Spondylitis ◽  
Iga Nephropathy

IgA Nephropathy in a Young Female with Ankylosing Spondylitis

Rheumatology ◽  
1987 ◽  
Vol 26 (5) ◽  
pp. 396-397 ◽  
Author(s):  
E. KANTEREWICZ ◽  
R. SANMARTI ◽  
A. COLLADO ◽  
M. A. BRANCOS ◽  
A. TORRAS ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Iga Nephropathy ◽  
Young Female

scholarly journals A case of ankylosing spondylitis associated with IgA nephropathy.

1988 ◽  
Vol 77 (12) ◽  
pp. 1888-1889
Author(s):  
Yuji NAKAMURA ◽  
Hiroko UTSUNOMIYA ◽  
Keiko YOSHIMOTO ◽  
Masahiko OKADA ◽  
Shigeki SAIMA
Keyword(s):  
Ankylosing Spondylitis ◽  
Iga Nephropathy

Onset of IgA nephropathy in a patient treated with infliximab for ankylosing spondylitis

2021 ◽  
Vol 14 (1) ◽  
pp. e237713
Author(s):  
Charlotte Anne Baert ◽  
Selda Aydin ◽  
Philippe Leroy ◽  
Patrick Durez
Keyword(s):  
Renal Function ◽  
Ankylosing Spondylitis ◽  
Kidney Disease ◽  
Iga Nephropathy ◽  
Clinical Case ◽  
Urine Analysis ◽  
Immune Dysregulation ◽  
Puncture Biopsy ◽  
Necrosis Factor

We report the case of a 43-year-old man, suffering from ankylosing spondylitis and treated with Infliximab 5 mg/kg every 2 months, with an excellent disease control. During a follow-up consultation, an incipient renal insufficiency is detected. A urine analysis showed haematuria and proteinuria and a renal puncture-biopsy revealed an image of IgA nephropathy.Several cases of IgA nephropathy have been reported in the literature associated with ankylosing spondylitis. Some of them occur in patients treated with antitumour necrosis factor, but it is unclear whether this pathology is caused by the treatment or whether treatment failed to prevent its occurrence.Our clinical case highlights the importance of regular monitoring of renal function in patients with ankylosing spondylitis, as well as urinary spotting.The question of whether the disease itself, the treatment or other factors such as immune dysregulation could be held responsible for kidney disease will be addressed in the discussion.

scholarly journals IgA nephropathy associated with ankylosing spondylitis: occurrence in women as well as in men.

1989 ◽  
Vol 48 (5) ◽  
pp. 435-437 ◽  
Author(s):  
K N Lai ◽  
P K Li ◽  
B Hawkins ◽  
F M Lai
Keyword(s):  
Ankylosing Spondylitis ◽  
Iga Nephropathy

P0136COMPARISON OF SECONDARY IGA NEPHROPATHY OF ANKYLOSING SPONDYLITIS AND PRIMARY IGA NEPHROPATHY IN CLINICAL AND PATHOLOGICAL FEATURES

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Qin Xue ◽  
Guang Li Zhang ◽  
Zebo Tian
Keyword(s):  
Retrospective Study ◽  
Ankylosing Spondylitis ◽  
Iga Nephropathy ◽  
Interstitial Fibrosis ◽  
Renal Involvement ◽  
Control Group ◽  
Pathological Features ◽  
Tubular Atrophy ◽  
The Difference ◽  
Clinical And Pathological Features

Abstract Background and Aims Renal involvement is one of the most common extra-articular complications caused by ankylosing spondylitis (AS). The main pathological manifestation is secondary IgA nephropathy(SIgAN) in Chinese AS patients. The difference between SIgAN and primary IgAN (PIgAN) remains unclear due to the lack of cases. Therefore, the aim of this retrospective study was to compare the clinical and pathological features of SIgAN of AS (SIgAN-AS) and PIgAN, to detect the pathogenesis of SIgAN Method Clinical characteristics and pathological data were collected in patients who were diagnosed with IgAN by renal biopsy in our hospital from Jan 2008 to Oct 2018. Patients with SIgAN-AS were recruited by the ratio 1:5 of patients with primary IgAN as the control group in the study. Fifteen patients with SIgAN-AS and Seventy-five patients with PIgAN were enrolled in this retrospective study. Results There were 15 cases in AS group, including 13 male and 2 female. The cohort of 75 patients with PIgAN included 34 male and 41 female. There were more males in AS group 13/15 (86.7%) vs 37/75(49.3%) ,P < 0.05. Compared with PIgAN patients, SIgAN-AS patients had higher incidences of hematuria( 13/15(86.7%)vs 44/75 (58.7%) , P < 0.05), lower levels of 24-hour urinary protein(0.85±0.68 vs 1.57±1.54g, P < 0.05), but higher levels of eGFR (CKD-MDRD formula) (117.60±37.33 vs 85.35±31.36, P < 0.05),eGFR (CKD-EPI formula) (128.01±41.58 vs 92.75±36.09, P < 0.05), Albumin (44.67±3.48 vs 41.09±7.07 g/L, P < 0.05) ESR (43.20 ±33.94 vs 18.79±16.26mm/h, P < 0.001) , and CRP (21.19±30.61 vs 2.11±4.58mg/L, P < 0.001) . From the perspective of renal pathology of PIgAN, SIgA-AS patients had fewer incidences of renal tubular atrophy / interstitial fibrosis of nephropathy (P <0.05). The immunohistostaining analysis showed higher incidences of dominant deposits of single IgA in mesangial cell area (P < 0.05). Conclusion Patients with SIgAN-AS is more common in male and display a milder progression than those with primary IgAN. Majority of the SIgAN-AS can be improved with early intervention.

Comparison of secondary IgA nephropathy in patients with ankylosing spondylitis and rheumatoid arthritis

2019 ◽  
Vol 30 (4) ◽  
pp. 648-656 ◽  
Author(s):  
Dafeng He ◽  
Rong Wang ◽  
Shaoshan Liang ◽  
Dandan Liang ◽  
Feng Xu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankylosing Spondylitis ◽  
Iga Nephropathy

scholarly journals IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept

2018 ◽  
Vol 33 (1) ◽  
pp. 85
Author(s):  
Do-Hyeong Lee ◽  
Geun-Tae Kim ◽  
Na-Kyoung Hwang ◽  
Eun-Heui Kim
Keyword(s):  
Ankylosing Spondylitis ◽  
Iga Nephropathy
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