scholarly journals Effect of estrogen receptor, follicle stimulating hormone and myogenin genes on the performance of Large White sows

2008 ◽  
Vol 52 (No. 10) ◽  
pp. 334-340 ◽  
Author(s):  
P. Humpolíček ◽  
T. Urban ◽  
V. Matoušek ◽  
Z. Tvrdoň
Keyword(s):  
Estrogen Receptor ◽  
Litter Size ◽  
Growth Traits ◽  
Receptor Gene ◽  
Follicle Stimulating Hormone ◽  
Average Daily Gain ◽  
Large White ◽  
Meat Content ◽  
Reproduction Traits ◽  
Stimulating Hormone

The study was designed to determine the associations between the Estrogen Receptor Gene (<i>ESR - PvuII</i>), Follicle Stimulating Hormone Gene (<i>FSHB - HaeIII</i>) and Myogenin Gene (<i>MYOG - MspI</i>) with traits characterizing the sow efficiency comprehensively. Concretely, the age of the first conception (AFC), service period (SP), insemination interval (InI), total number of piglets born (TNB), number of piglets born alive (NBA), number of piglets weaned (NW), lean meat content (LMC), backfat thickness (BFT) and average daily gain (ADG) were included in the study. Significant effects of <i>ESR</i> and <i>FSHB</i> genes on litter size (particularly in the second parity) and on reproduction traits were found in the investigated population. The influence of <i>MYOG</i> gene on reproduction traits was observed but there was no effect of this gene on litter size. None of the included genes had an effect on growth traits. The results outline the possible application of the above-mentioned genes in selection of Large White sows.

scholarly journals Porcine prolactin receptor genotypes and production and reproduction traits in Hungarian Large White and Landrace sows (Brief Report)

2010 ◽  
Vol 53 (4) ◽  
pp. 497-499
Author(s):  
K. Kovacs ◽  
L. Fesus ◽  
A. Zsolnai ◽  
A. Nyiri ◽  
I. Anton
Keyword(s):  
Litter Size ◽  
Receptor Gene ◽  
Mammalian Species ◽  
Prolactin Receptor ◽  
Reproductive Traits ◽  
Pituitary Hormone ◽  
Chromosome 16 ◽  
Large White ◽  
Anterior Pituitary Hormone ◽  
Reproduction Traits

Abstract. Prolactin is an anterior pituitary hormone involved in many endocrine activities and plays and essential role in reproduction. Its receptor (PRLR) was detected in various tissues including brain, ovary, placenta, an uterus in several mammalian species (BOLE-FEYSOT et al. 1998). Reproductive performance of sows is a crutial point in pig production with significant economic importance and may be estimated with the help of markers. Porcine prolactin receptor gene is said to be a candidate genetic marker for reproductive traits. It has been mapped to porcine chromosome 16 (Vincent et al. 1997). There is a C/G SNP in PRLR gene (KMIEC et al. 2001) at the position of 203 (GAN: U96306) which eliminates an AluI cleavage site. The effect of this polymorphism on litter size in various breeds has been estimated (VINCENT et al. 1998, ROTHSCHILD et al. 1998, VAN RENS et al. 2002, KMIEC and TERMAN, 2004, DRÖGEMÜLLER et al. 2001, KORWIN-KOSSAKOWSKA et al. 2003). The influence of the bovine hormone variant was also estimated (RATNA-KUMARI et al. 2008). The aim of the study was to estimate PRLR AluI polymorphism effects on litter size in Hungarian Large White (HLW) and Hungarian Landrace (HL) breeds.

scholarly journals Missense mutations in exon 2 of the porcine leptin receptor gene and their associations with litter size and body weight

2009 ◽  
Vol 54 (No. 5) ◽  
pp. 210-216 ◽  
Author(s):  
C. Sun ◽  
L. Wang ◽  
D.F. Jiang ◽  
B. Zhang
Keyword(s):  
Litter Size ◽  
Leptin Receptor ◽  
Receptor Gene ◽  
Average Daily Gain ◽  
Live Weight ◽  
Gene Marker ◽  
Missense Mutations ◽  
Production Traits ◽  
Large White ◽  
Exon 2

Leptin receptor (<I>LEPR</I>) gene is regarded as a “candidate-gene” of production traits. The aims of this study were to detect polymorphisms of exon 2 within <I>LEPR</I> gene and to investigate their associations with production traits, litter size and live weight in Luchuan and Large White pig breeds. For this purpose, the single nucleotide polymorphisms (SNPs) of exon 2 within <I>LEPR</I> were detected using the PCR-SSCP procedure and their association with litter size and live weight was also analysed in Luchuan (<I>n</I> = 446) and Large White pigs (<I>n</I> = 405). The results showed that the C155T mutation was found in exon 2 of porcine <I>LEPR</I> gene in analyzed populations, which caused a missense mutation (Met to Thr). The different genotypes of this locus had the effects on total number of piglets born, born alive of the first (1<sup>st</sup>) and the first to the fourth (1<sup>st</sup>–4<sup>th</sup>) litters. The individuals with allele <I>A</I> had a higher number of total piglets born and a higher number of born alive piglets in the first litter (<I>P</I> < 0.05) while the differences in birth weight, weaning weight and average daily gain were not significant among different genotypes of this locus in analyzed populations. It implies that the exon 2 (Thr/Met) mutation of <I>LEPR</I> gene is a potential gene marker of pig reproduction. Therefore, it can be used in the marker-assisted selection (MAS) of pig breeding work.

scholarly journals Simultaneous estimation of genetic parameters for production and litter size traits in Czech Large White and Czech Landrace pigs

2013 ◽  
Vol 58 (No. 9) ◽  
pp. 429-436 ◽  
Author(s):  
E. Krupa ◽  
J. Wolf
Keyword(s):  
Litter Size ◽  
Genetic Parameters ◽  
Genetic Evaluation ◽  
Simultaneous Estimation ◽  
Large White ◽  
Lean Meat ◽  
Absolute Value ◽  
Meat Content ◽  
Reproduction Traits ◽  
Daily Gain

Genetic parameters for total number of piglets born per litter, number of piglets weaned per litter, lean meat content, and average daily gain from birth till the end of the field test were estimated for Czech Large White (445 589 records) and Czech Landrace (149 057 records) pigs using a four-trait animal model. The following heritabilities were estimated (first number: Large White, second number: Landrace): 0.10 &plusmn; 0.004 and 0.09 &plusmn; 0.007 for total number born; 0.09 &plusmn; 0.005 and 0.07 &plusmn; 0.008 for number weaned; 0.39 &plusmn; 0.004 and 0.36 &plusmn; 0.009 for lean meat content; 0.21 &plusmn; 0.004 and 0.18 &plusmn; 0.006 for daily gain. The highest genetic correlation (approximately 0.85 in both breeds) was estimated between both litter size traits. In Czech Landrace, all remaining genetic correlations were &lt; 0.20 in their absolute value. Negative correlations of approximately ‑0.25 were estimated in Czech Large White between daily gain and both reproduction traits. All remaining correlations in Czech Large White were also &lt; 0.20 in their absolute value. The estimated non-zero correlations between production and reproduction traits are, besides of other arguments, one reason to recommend a joint genetic evaluation of production and reproduction traits. If more than one litter trait is included in the genetic evaluation, repeatability models should be used instead of separate treating the first and the second and subsequent litters; this is because of the high correlations among litter size traits which are expected to cause numerical problems if multi-parity models are used. &nbsp;

scholarly journals Herd specific effects of the ESR gene on litter size and production traits in Czech Large White sows

2011 ◽  
Vol 49 (No. 9) ◽  
pp. 373-382 ◽  
Author(s):  
E. Goliášová ◽  
J. Wolf
Keyword(s):  
Animal Models ◽  
Litter Size ◽  
Receptor Gene ◽  
Average Daily Gain ◽  
Production Traits ◽  
Large White ◽  
Specific Effects ◽  
White Breed ◽  
Pvuii Polymorphism ◽  
Esr Gene

The effect of PvuII polymorphism of the oestrogen receptor gene on litter size and production traits in a Czech Large White population (882 sows, 2 455 litters) was evaluated. Data were analysed by four four-trait animal models. The traits analysed were lifetime average daily gain in the field test, lean meat percentage, number of piglets born alive in parity 1 and number of piglets born alive in parity 2 and subsequent parities. The animal models differed in considering the herd-year-season effect as random or fixed and in including or not including the dominance effect. For each model two variants were calculated: the ESR effects were calculated either across herds or within herds. On the genetic level, no significant overall effects of the ESR gene were detected. The effects of the ESR gene within herds were mostly insignificant as well. There was a certain tendency for allele A to increase litter size in parity 1. Nevertheless, on the basis of the present knowledge, the use of the ESR gene for selection for litter size in the Czech Large White breed seems to be of questionable benefit and cannot be recommended. &nbsp;

Evaluation of genetic markers for litter size in Meishan synthetic and Large White pigs

1996 ◽  
Vol 1996 ◽  
pp. 18-18
Author(s):  
O.I. Southwood ◽  
S. Hoste ◽  
T.H. Short ◽  
A.J. Mileham ◽  
D. Cuthbert-Heavens
Keyword(s):  
Litter Size ◽  
Fixed Effects ◽  
Oestrogen Receptor ◽  
Mixed Model ◽  
Receptor Gene ◽  
Large White ◽  
Service Type ◽  
Sib Families ◽  
Natural Service ◽  
Size Data

A significant relationship between the oestrogen receptor gene (ESR) and litter size has been detected in USA populations of Large White and a synthetic comprising 50% Meishan (Rothschild et al., 1995). Animals carrying two copies of the favourable allele (B) had an extra pig born per litter than those that did not have the allele. This paper reports on results observed in a UK 50% Meishan synthetic and four UK Large White lines.Litter size data from 50% Meishan synthetic (L93) full-sib females where more than one ESR genotype was segregating. Data were analysed using a mixed model with full relationships and including the fixed effects of season of farrowing, parity, ESR genotype (AA, AB or BB) and service type (AI or natural service). Heritiability and permanent environmental effects for litter size were assumed as 0.09 and 0.11, repectively. A total of 27 full-sib families were represented and included 62 sows and 139 litter records. Hypothesis testing used the option in PEST under a mixed model (Groeneveld et al., 1991).

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