Effects on growth performance, faecal microflora and plasma cholesterol after supplementation of spray-dried metabolite to postweaning rats
A study was conducted to study the effects of feeding a spray-dried metabolite (SDM) produced by <i>Lb. Plantarum</i> I-UL4 in the diets of postweaning rats on growth performance, faecal pH, <i>Enterobacteriaceae</i> bacterial and lactic acid bacteria (LAB) counts in the faeces and on plasma cholesterol concentrations. A total of 15 female 4-weeks-old <i>Sprague dawley</i> rats were randomly assigned to 3 groups of diets: basal diet (control), 0.25% SDM and 0.5% SDM diets. Daily feed intake, daily growth rate, blood plasma for total cholesterol concentration and faecal <i>Enterobacteriaceae</i> and LAB were measured. The growth rate, total feed intake, feed conversion ratio, and pH were not significantly different (<i>P</i> > 0.05) among all the treatment groups. The faecal <i>Enterobacteriaceae</i> counts in the 0.25% and 0.5% groups were significantly (<i>P</i> < 0.05) lower than in the control group. However, there was no significant difference (<i>P</i> > 0.05) in the LAB counts among all the treatment groups. The plasma cholesterol concentration was significantly reduced (<i>P</i> < 0.05) following the feeding of the metabolite. The control had the highest concentration of cholesterol. However, the 0.5% SDM group had the lowest plasma cholesterol concentration, followed by the 0.25% SDM group.