scholarly journals Effects of sweetener sucralose on diet preference, growth performance and hematological and biochemical parameters of weaned piglets

2020 ◽  
Vol 33 (5) ◽  
pp. 802-811 ◽  
Author(s):  
Wenwei Zhang ◽  
Holden He ◽  
Limin Gong ◽  
Wenqing Lai ◽  
Bing Dong ◽  
...  

Objective: Two experiments were conducted to investigate the effects of dietary sucralose on diet preference and growth performance of weaned piglets, and a third experiment was a 28-d safety study to examine if high-dose sucralose could affect the health state of weaned piglets.Methods: In experiment one, 48 piglets had free access to a corn-soybean based diet and the same diet supplemented with 150 mg/kg sucralose for 15 d. In experiment two, 180 piglets were blocked into 5 treatments with 6 replications. They were fed basal diets supplemented with 0, 75, 150, 225, and 300 mg/kg sucralose for 28 days. In experiment three, 108 piglets were randomly assigned to 3 treatments and fed diets supplemented with 0, 150 (suitable level), and 1,500 (ten-fold suitable level) mg/kg sucralose for 28 d.Results: The experiment 1 showed that piglets preferred (p<0.05) diets containing sucralose during experimental period. In experiment 2, piglets fed a diet supplemented with 150 mg/kg sucralose had a higher average daily gain (ADG) and average daily feed intake (ADFI) than pigs in the control group and other treatment groups during the experiment period. The concentrations of sucralose over 150 mg/kg may decrease feed intake. However, no difference in feed conversion ratio was observed. In experiment 3, piglets fed diet supplemented with 150 mg/kg sucralose had a higher ADG and ADFI than that of pigs in the control group and 1,500 mg/kg treatment groups during the experiment period. Clinical blood metabolites, organ index and histological morphology were not significantly different between sucralose treatments.Conclusion: Sucralose can promote feed intake and thereby improve growth performance of weaned piglets. Moreover, inclusion of 1,500 mg/kg sucralose was demonstrated to have no observed adverse effects. Supplementing 150 mg/kg sucralose for weaned piglets is recommended in this study.

2009 ◽  
Vol 147 (5) ◽  
pp. 625-631 ◽  
Author(s):  
L. L. LI ◽  
X. WU ◽  
H. Z. PENG ◽  
M. Z. FAN ◽  
Z. P. HOU ◽  
...  

SUMMARYThe present study was conducted to determine the effects of a polysaccharide of Atractylodes macrophala Koidz (PAM) as a dietary additive on growth performance, immunoglobulin concentration and IL-1β expression in weaned piglets. One hundred and twenty Landrace×Yorkshire piglets weaned at 28 days old (body weight 7·5±0·07 kg) were assigned to five treatment groups (three pens/group, eight piglets/pen) fed maize/soybean-based diets supplemented with 0, 3, 6 or 9 g of PAM/kg diet or antibiotics (0·4 g flavomycin/kg+0·13 g olaquindox/kg). The experimental period was 28 days. With increasing PAM supplementation levels, average daily gain was greater (quadratic, P<0·05) and the ratio of amount fed to live weight (LW) gain (feed/gain) improved (quadratic, P<0·05) during days 14–28 and overall, and diarrhoea incidence decreased (linear, P<0·05) during days 14–28. Supplementation of PAM also increased (quadratic, P<0·05) serum concentrations of interleukin (IL)-2 and IL-6 on day 14, and increased (quadratic, P<0·05) IL-1β expression in jejunal mucosa and lymph nodes. Concentrations of PAM between 6 and 9 g/kg presented the strongest bioactivity compared to the control group or antibiotic-fed group. These findings indicate that PAM is effective in improving growth performance and cytokine response, which suggests that PAM can be used as a diet additive for weanling piglets.


Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2104
Author(s):  
Qi Wang ◽  
Jiafu Ying ◽  
Peng Zou ◽  
Yuanhao Zhou ◽  
Baikui Wang ◽  
...  

At present, the widespread use of high-dose zinc oxide and antibiotics to prevent post-weaning diarrhea (PWD) in piglets has caused serious environmental problems. To solve this problem, we studied the effect of HNa as a substitute for zinc oxide (ZnO) and antibiotics on the growth performance, immune status, and antioxidant capacity of piglets. Seventy-two weaned piglets (body weight = 7.42 ± 0.85 kg, 26-d-old) were distributed in a randomized 2 × 3 factorial design (two sexes and three treatments) with six replicates of four piglets each. The three treatments were the control diet (basic diet), HNa diet (basic diet + 2000 mg/kg sodium humate), and ZoA group (basic diet + 1600 mg/kg zinc oxide + 1000 mg/kg oxytetracycline calcium). ANOVA and Chi-square tests were applied to compare the means (p < 0.05) between treatments. The results showed that body weight at 16 and 30 d and the average daily gain of piglets fed with HNa or ZoA were significantly higher (p < 0.05) than the control group. Supplementing HNa or ZoA significantly increased (p < 0.05) the level of immunoglobulin M and G, and reduced (p < 0.05) the concentration of inflammatory factors such as tumor necrosis factor-alpha (TNF-α), interleukins IL-6 and IL-1β, myeloperoxidase (MPO), and diamine oxidase (DAO). Furthermore, dietary HNa or ZnO significantly reduced (p < 0.05) the level of total antioxidant capacity (T-AOC) and malondialdehyde (MDA) compared with the control group. ZoA treatment showed an upward trend of IgA level and a downward trend of the concentration of lipopolysaccharide (LPS) and catalase (CAT). Overall, the study demonstrated that the addition of HNa in the diet partially replaced antibiotics and ZnO to improve the growth performance, immune function, and antioxidant capacity of weaned piglets, and maintained a good preventive effect on piglet diarrhea.


2014 ◽  
Vol 59 (No. 5) ◽  
pp. 247-253 ◽  
Author(s):  
S. Mohana Devi ◽  
US Devi ◽  
IH Kim

A 6-week trial was conducted to investigate the effects of animal skin protein sources from swine and cattle on growth performance, body condition and blood characteristics in growing pigs. A total of 96 pigs (23.50 &plusmn; 0.61&nbsp;kg) were randomly allotted into four dietary treatment groups as follows: (1) basal diet (BD); (2) basal diet with 1.5% hydrolysed render meal (HRM); (3) basal diet with 1.5% swine skin meal (SSM); (4) basal diet with 1.5% cattle hide meal (CHM). There were six replicate pens per treatment with four pigs per pen. The average daily gain (ADG) was improved in response to SSM treatment compared with other treatments (P &lt; 0.05). Pigs fed with HRM, SSM and CHM diets showed increases in average daily feed intake (ADFI) and decreased gain-to-feed (G : F) ratios compared with pigs fed with BD (P &lt; 0.05). There were no differences in dry matter (DM), nitrogen (N), and energy (E) digestibility among treatments. The backfat thickness and lean percentage of pigs was unaffected by the treatments. Similarly, there was no difference in blood characteristics among treatments. In conclusion, the supplementation of SSM in growing pig diets improved the growth rate and Feed Intake (FI), but its usage in swine diets is limited by the poor protein quality. &nbsp;


2018 ◽  
Vol 58 (11) ◽  
pp. 2100 ◽  
Author(s):  
Don V. Nguyen ◽  
Bunmi S. Malau-Aduli ◽  
Peter D. Nichols ◽  
Aduli E. O. Malau-Aduli

The objective of this study was to investigate the effects of enriched omega-3 oil supplemental pellets, breed and gender on lamb liveweight (LWT), body conformation and carcass characteristics, and to assess the relationships between body conformation and growth under an intensive finishing condition. Sixty ewe and wether prime lambs 7 months old were randomly allocated to one of five dietary treatments: no oil inclusion (Control); 2.5% canola oil; 5% canola oil; 2.5% flaxseed oil and 5% flaxseed oil, balanced by breed (purebred Merinos (M × M) and Corriedale × Merino (C × M) and White Suffolk × Corriedale (W × C) first crosses). Lambs were individually supplemented with 1 kg pellets per day and had free access to lucerne hay and water throughout the 7-week feeding trial, after a 3-week adaptation. Dietary oil inclusion did not cause significant differences in daily feed intake, growth performance and carcass characteristics (P > 0.05). However, first-cross W × C lambs had significantly higher feed intake, chest girth and body conformation score (P < 0.05) than M × M and C × M lambs. Carcass weight, dressing percentage and fat depth of crossbred lambs were significantly higher than those of M × M (P < 0.05). Significant interactions between oil inclusion and breed on average daily gain (ADG) and feed conversion ratio were observed. There were positive and highly significant correlations among LWT, ADG and body conformation measurements (P < 0.01). These findings suggest that prime lamb producers can better manage and match their breeding goals with feed resources by supplementing first-cross C × M lambs with pellets containing 5% canola oil or feeding first-cross W × C lambs with 5% flaxseed oil pellets during the 10-week intensive finishing period.


Author(s):  
MM Rahman ◽  
NR Sarker ◽  
MA Alam

This study was carried out to evaluate the feeding effect of high yielding fodders (HYF) on feed intake and growth performance of growing Hilly Brown Bengal (HBB) goat. For this purpose, a feeding trail was conducted with 16 growing HBB kids (4 to 5 months) by dividing equally in four groups having four replicates for a period of 75 days. The goats in group T0 (control) received natural grass along with 101.30g concentrates and adlibitum cowpea hay, whereas in group T1, T2 and T3, only natural grass was replaced by BLRI Napier 3, BLRI Napier 4 and Ruzi fodder, respectively. Total dry matter intake (DMI), roughages DMI, crude protein intake (CP), body weight gain (kg), average daily gain (g) and forth night body weight gain (g/day) were studied. Results revealed that, DMI (288.39, 285.71, 293.48 and 301.35 g/day in group T0, T1, T2 and T3, respectively), body weight gain (3.60, 3.74, 3.73 and 3.77 kg in group T0, T1, T2 and T3, respectively), average daily gain (47.32, 49.16, 49.12 and 48.92 g in group T0, T1, T2 and T3, respectively) and feed conversion ratio (6.2, 5.9, 6.0 and 6.1 in group T0, T1, T2 and T3, respectively) of HBB kids were not differed significantly (P>0.05) for all the treatment groups. The DMI from roughages (196.2, 193.5, 201.3 and 209.2 g/day in group T0, T1, T2 and T3, respectively) and CP intake (38.7, 42.1, 48.3 and 38.8 g/day in group T0, T1, T2 and T3, respectively) were significantly varied (P<0.05), while highest CP intake was found in the treatment group T2. Forthnight body weight (g/day) was not significantly (P>0.05) gained with feeding of HYF for all the treatment groups. From this study, it can be concluded that, growing HBB kids could equally be supplied with either BLRI Napier 3 or BLRI Napier 4 or Ruzi fodder in addition to ad libitum cowpea hay for better voluntary feed intake and growth. Bang. J. Livs. Res. Vol. 27 (1&2), 2020: P. 73-81


2020 ◽  
Author(s):  
Zhenguo Yang ◽  
Yao Wang ◽  
Tianle He ◽  
Ziema Bumbie Gifty ◽  
Zhihong Sun ◽  
...  

Abstract BackgroundEconomic benefit is an important goal pursued by animal husbandry industry. The emergence of antibiotics has promoted the development of animal husbandry, but many problems caused by the abuse of antibiotics have caused concerns about the use of antibiotics from all walks of life. Therefore, it is imperative to find alternatives to antibiotics. A large number of studies have shown that plant extracts and probiotics have certain potential in improving animal growth performance, antioxidant capacity and immune function. The purpose of this study was to explore the effects of Yucca Shidigera Extract (YSE) and Candida Utilis (CU) on weaned piglets. We compared and evaluated the effects of YSE and CU on weaned piglets from the aspects of growth performance, immunity, antioxidant function, ileal morphology and microflora changes. Forty 28-day-old healthy weaned piglets (Rongchang pig×Landrace×Large white) were randomly divided into 4 treatments: (1) control group (CON); (2) CU; (3) YSE; (4) CU+YSE. ResultsOur results showed that YSE and CU improved the growth performance by significantly increasing final weight, average daily gain (ADG) (P < 0.05), and there is decreasing trend of feed/gain ratio (P=0.087). The effect of adding YSE or CU alone on growth performance had little difference, and the effect of oral CU was slightly better than that of adding YSE. At the same time, the combination of YSE and CU had a good effect on reducing the diarrhea rate. In addition, both YSE and CU increased the diversity of cecal microflora, and CU increased the diversity more significantly, but did not change the dominant microflora of cecum. We also found that the addition of YSE and CU could maintain the structural integrity of intestinal tissue and regulate intestinal pH, to maintain the level of intestinal-associated immune proteins. At the same time, YSE and CU have certain benefits in regulating intestinal flora. ConclusionYSE and CU can improve the growth performance, reduce the diarrhea rate, improve intestinal health, and increase the diversity and abundance of cecal microflora in weaned piglets. Therefore, they are expected to be used as probiotics in the production of weaned piglets.


Author(s):  
Shi Wenying ◽  
Lu Chunlian ◽  
Li Shang ◽  
Song Jiachun ◽  
Cao Hongzhan

Background: This study was conducted to evaluate the effects of different levels of citric acid (CA) on the growth performance, nutrient digestibility and gastrointestinal pH of weaned piglets. Methods: A total of 120 weaned piglets with an initial BW of 7.15±0.01 kg, were randomly divided into four groups including control treatment each with three replicates of 10 piglets each. Each group was supplemented with 0.5% (control group), 1%, 1.5% and 2% CA in the basal diet, respectively. Result: The results showed that the average daily feed intake (ADFI) and average daily gain (ADG) of added 1% CA group were significantly higher than that of 0.5% group (P less than 0.05). Dietary CA significantly improved the utilization rates of crude protein, calcium and phosphorus (P less than 0.05), while there was no significant difference between adding 1% and 1.5% CA (P greater than 0.05). Compared with the control group, adding CA effectively reduced the pH of the stomach, duodenum jejunum and ileum contents and adding 2% CA were significantly lower than those in other groups (P less than 0.05). Therefore, the addition of 1.0% CA in the diets of weaned piglets is suitable.


Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1330 ◽  
Author(s):  
Xiaoshuai Chen ◽  
Haiming Yang ◽  
Lei Xu ◽  
Xiaoli Wan ◽  
Zhiyue Wang

This study investigated the effect of replacing dietary corn with broken rice (BR) on goose growth performance, body size and bare skin color. In total, 240 28-day-old healthy male Yangzhou goslings with similar body weight (BW) were randomly divided into five groups, with six replicates per group and eight geese per replicate. The control group was fed with a corn-soybean meal. The BR25, BR50, BR75 and BR100 groups had 25%, 50%, 75% and 100% of corn replaced with BR, respectively (corresponding to 15.95%, 31.88%, 47.63% and 62.92% of BR in the feed, respectively), each with constant metabolizable energy (ME) to crude protein (CP) ratio (ME/CP). At 28, 42, 56 and 70 d, BW and feed intake for each pen were measured. Blood was collected, and body size and bare skin color were evaluated at 70 d. The results showed that different BR replacement proportions had no effect on BW at 42, 56 or 70 d or on average daily feed intake (ADFI) or average daily gain (ADG) from 28 to 42 d (p > 0.05) but BR50 and BR75 decreased the feed/gain ratio (F/G) from 28 to 42 d (p < 0.05). From 42 to 56 d, BR75 and BR100 geese had a lower ADFI than the control geese (p < 0.05), and BR75 and BR100 geese had a lower F/G than the BR25 geese (p < 0.05). Group BR50, BR75 and BR100 geese had a lower ADFI from 56 to 70 d than the control geese (p < 0.05). From 28 to 70 d, BR50, BR75 and BR100 groups had a lower ADFI (p < 0.05). Interestingly, the control and BR25 groups had a higher flipper score than the BR50, BR75 and BR100 groups (p < 0.05), and the control group had a higher flipper score than the BR25 group (p < 0.05). All BR groups reduced the bill scoring (p < 0.05). Different BR replacement proportions did not negatively affect serum biochemical variable at 70 d (p > 0.05). Overall, under these conditions, BR can totally replace corn in goose diets, and we recommend 75% replacement of corn with BR from 28 to 70 d.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 414-414
Author(s):  
Shiqin Wang ◽  
Qiyu Diao ◽  
Kai Cui ◽  
Yanliang Bi ◽  
Naifeng Zhang

Abstract The objective of this study was to evaluate the effects of early weaning on growth performance, feed intake and diarrhea rate of Hu lambs, and establish the experimental model of early weaning stress in lambs. A total of 60 neonatal male Hu lambs were randomly allotted into 10 pens and 6 lambs in each pen with their ewes. Five pens of lambs were weaned at 21days of age as early weaning group (EW group), and the other 5 pens of lambs were remained with their ewes as control group (CON group). Body weight (BW) were recorded at birth (d0) and at d7, 14, 21, 22, 24, 26, 28, 35,42 and 49 after birth. Solid feed intake of lambs in each pen was recorded and diarrhea incidence was also monitored on daily basis. Data was analyzed using the MIXED model of SAS, and statistical significance was determined at P &lt; 0.05. There was no difference in BW at birth and d21 between the two groups of lambs (P &gt; 0.05). However, BW and average daily gain (ADG) of the lambs in EW group were significantly lower than those in CON group (P &lt; 0.01) since weaning. Solid feed intake of the lambs in EW group were obviously higher than that in CON group (P &lt; 0.01). In addition, the diarrhea rate was significantly higher than that in CON group from d21 to d35 (P &lt; 0.01). The results indicated that lambs weaned at d21 showed strong stress response by significantly decreasing in BW and ADG, and had more feed intake but higher diarrhea rate. Future study is warranted to determine the changes in gut microbiota and barrier function to assess the mechanism of early weaning on health status and growth performance of lambs, and to investigate nutritional intervention methods to alleviate weaning stress.


2020 ◽  
Author(s):  
Hang Zhao ◽  
Saikun Pan

Abstract Background: The present study aimed to explore the effects of dietary chitosan oligosaccharides (COs) on the growth performance and immunity of broiler chickens.Methods: Four test diets were supplemented with different doses of COs (0, 50, 100 and 150 mg/kg) and formulated. Triplicate groups of broiler chickens were fed with one of the diets ad libitum for 6 weeks. Results: After the end of the feeding trials, oral CO administration improved average daily gain; the activities of digestive amylase, lipase and protease; the activities of serum superoxide dismutase and glutathione peroxidase; serum tumor necrosis factor-α, interleukin (IL)-1, IL-2, IgG, IgM and IgA levels; and reduced feed conversion ratio and malondialdehyde level compared with those of the control group. However, a high dose of CO (150 g/kg) did not further increase its efficiency compared with the moderate dose of CO (100 g/kg). Conclusions: Oral CO administration improved the growth performance and immunity of juvenile broiler chickens and could be used as a feed supplement.


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