scholarly journals The phospholipid fraction obtained from egg yolk reduces blood pressure increase induced by acute stress in spontaneously hypertensive rats

2018 ◽  
Vol 27 (12) ◽  
pp. 1745-1749
Author(s):  
Helena Martynowicz ◽  
Dorian Nowacki ◽  
Grzegorz Mazur ◽  
Tadeusz Trziszka ◽  
Andrzej Szuba
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Acute Stress ◽  
Egg Yolk ◽  
Phospholipid Fraction ◽  
Pressure Increase ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Blood Pressure Increase

Plant sterols and casein-derived tripeptides attenuate blood pressure increase in spontaneously hypertensive rats

2012 ◽  
Vol 32 (4) ◽  
pp. 292-300 ◽  
Author(s):  
Pauliina I. Ehlers ◽  
Anne S. Kivimäki ◽  
Aino Siltari ◽  
Anu M. Turpeinen ◽  
Riitta Korpela ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Plant Sterols ◽  
Pressure Increase ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Blood Pressure Increase

Maternal influences on sympathetic-adrenal medullary system in spontaneously hypertensive rats

1990 ◽  
Vol 258 (5) ◽  
pp. H1312-H1316
Author(s):  
M. A. Cierpial ◽  
M. Konarska ◽  
R. McCarty
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Acute Stress ◽  
Hypertensive Rats ◽  
Blood Pressure Lowering Effect ◽  
Maternal Environment ◽  
Spontaneously Hypertensive ◽  
Arterial Blood ◽  
Wistar Kyoto ◽  
Cross Fostering

The technique of reciprocal cross fostering was used to assess the influence of the maternal environment on the functioning of the sympathetic-adrenal medullary system in the spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) normotensive rats. Control, in-fostered, and cross-fostered rats were tested in adulthood to assess 1) the neural contribution to resting mean arterial blood pressure (MAP) and 2) sympathetic-adrenal medullary responses to acute footshock stress. Adult resting MAP was significantly lower in cross-fostered SHRs (139.6 mmHg) compared with control or in-fostered SHRs (162.1 and 159.3 mmHg). In addition, the decrease in MAP after sympathetic blockade (40.6 mmHg) was significantly less in cross-fostered SHRs compared with controls (50.1 mmHg). Sympathetic-adrenal medullary responses to foot-shock were greater in SHR than WKY rats; however, cross-fostered SHRs showed exaggerated responses compared with control and in-fostered SHRs. Altering the maternal environment did not produce any measurable effects on the neural contribution to resting MAP or sympathetic-adrenal medullary responsivity to acute stress in the WKY strain. These results indicate that the blood pressure-lowering effect of cross fostering in the SHR strain is caused in part by a dampening of the neural contribution to resting MAP; however, these animals retain their strain's characteristic adrenergic hyperreactivity to stressful stimulation.

Reduction of pressor response to stress by centrally acting apelin in spontaneously hypertensive rats

2014 ◽  
Vol 0 (0) ◽  
Author(s):  
Ryszard Stefan Gomolka ◽  
Agnieszka Cudnoch-Jedrzejewska ◽  
Katarzyna Czarzasta ◽  
Ewa Szczepanska-Sadowska
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rats ◽  
Acute Stress ◽  
Pressor Response ◽  
Cardiovascular Responses ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Air Jet ◽  
Arterial Blood ◽  
Response To Stress

AbstractNumerous studies suggest that apelin plays a significant role in cardiovascular regulation and in the pathogenesis of hypertension. The purpose of the present study was to determine whether apelin-13 (AP-13) is involved in the regulation of cardiovascular responses to acute stress in spontaneous hypertension.The effects of intracerebroventricular (ICV) administration of AP-13 on changes in mean arterial blood pressure (MABP) and heart rate evoked by an alarming stress (air jet stress) were compared in awake normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). The rats were divided into four groups: Groups 1 (WKY) and 3 (SHR) received ICV infusion of 0.9% sodium chloride (vehicle), whereas Groups 2 (WKY) and 4 (SHR) were ICV infused with AP-13. All animals were exposed to the alarming stress.During the ICV administration of the vehicle, the pressor response to stress was significantly greater in SHR than in WKY. The ICV infusion of AP-13 reduced the pressor response evoked by the application of the stressor in SHR but not in WKY. It also abolished the difference in stress-induced MABP increases between WKY and SHR.The results show that centrally acting apelin may play an essential role in the regulation of blood pressure responses to an alarming stress in SHR rats.

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