scholarly journals Cerebral blood flow and metabolism during hyperperfusion after cerebral revascularization for Moyamoya disease

2018 ◽  
Vol 30 (1) ◽  
pp. 47-51
Author(s):  
Yasuyuki Kaku
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Cerebral Revascularization

scholarly journals Paradoxical symptomatic cerebral blood flow decreases after combined revascularization surgery for patients with pediatric moyamoya disease: illustrative case

2022 ◽  
Vol 3 (3) ◽  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Upper Limb ◽  
Photon Emission ◽  
Cerebral Hemodynamics ◽  
Cerebral Revascularization ◽  
Left Internal Carotid Artery ◽  
Illustrative Case ◽  
Limb Weakness

BACKGROUND Transient neurological deficits (TNDs) develop after cerebral revascularization in patients with moyamoya disease (MMD). The authors report a rare pediatric MMD case with extensive decreased cerebral blood flow (CBF) and prolonged TNDs after combined revascularization. OBSERVATIONS A 9-year-old boy presented with transient left upper limb weakness, and MMD was diagnosed. A right-sided combined surgery was performed. Two years after the surgery, frequent but transient facial (right-sided) and upper limb weakness appeared. The left internal carotid artery terminal stenosis had progressed. Therefore, a left combined revascularization was performed. The patient’s motor aphasia and right upper limb weakness persisted for approximately 10 days after surgery. Magnetic resonance angiography showed that the direct bypass was patent, but extensive decreases in left CBF were observed using single photon emission tomography. With adequate fluid therapy and blood pressure control, the neurological symptoms eventually disappeared, and CBF improved. LESSONS The environment of cerebral hemodynamics is heterogeneous after cerebral revascularization for MMD, and the exact mechanism of CBF decreases was not identified. TNDs are significantly associated with the onset of stroke during the early postoperative period. Therefore, appropriate treatment is desired after determining complex cerebral hemodynamics using CBF studies.

Regional cerebral blood flow in pediatric moyamoya disease: age-dependent decline in specific regions

1998 ◽  
Vol 14 (8) ◽  
pp. 366-371 ◽  
Author(s):  
T. Ishikawa ◽  
Naruhiko Tanaka ◽  
Kiyohiro Houkin ◽  
Satoshi Kuroda ◽  
Hiroshi Abe ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Age Dependent

scholarly journals Relationships between hypercarbic reactivity, cerebral blood flow, and arterial circulation times in patients with moyamoya disease

2013 ◽  
Vol 38 (5) ◽  
pp. 1129-1139 ◽  
Author(s):  
Manus J. Donahue ◽  
Michael Ayad ◽  
Ryan Moore ◽  
Matthias van Osch ◽  
Robert Singer ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Arterial Circulation

scholarly journals Impact of blood pressure changes in cerebral blood perfusion of patients with ischemic Moyamoya disease evaluated by SPECT

2020 ◽  
pp. 0271678X2096745
Author(s):  
Zhao Liming ◽  
Sun Weiliang ◽  
Jia Jia ◽  
Liang Hao ◽  
Liu Yang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Moyamoya Disease ◽  
Emission Computed Tomography ◽  
Study Cohort ◽  
Pressure Changes ◽  
The Impact

Our aim was to determine the impact of targeted blood pressure modifications on cerebral blood flow in ischemic moyamoya disease patients assessed by single-photon emission computed tomography (SPECT). From March to September 2018, we prospectively collected data of 154 moyamoya disease patients and selected 40 patients with ischemic moyamoya disease. All patients underwent in-hospital blood pressure monitoring to determine the mean arterial pressure baseline values. The study cohort was subdivided into two subgroups: (1) Group A or relative high blood pressure (RHBP) with an induced mean arterial pressure 10–20% higher than baseline and (2) Group B or relative low blood pressure (RLBP) including patients with mean arterial pressure 10–20% lower than baseline. All patients underwent initial SPECT study on admission-day, and on the following day, every subgroup underwent a second SPECT study under their respective targeted blood pressure values. In general, RHBP patients showed an increment in perfusion of 10.13% (SD 2.94%), whereas RLBP patients showed a reduction of perfusion of 12.19% (SD 2.68%). Cerebral blood flow of moyamoya disease patients is susceptible to small blood pressure changes, and cerebral autoregulation might be affected due to short dynamic blood pressure modifications.

scholarly journals Imaging of cerebrovascular reserve and oxygenation in Moyamoya disease

2016 ◽  
Vol 37 (4) ◽  
pp. 1213-1222 ◽  
Author(s):  
Wendy W Ni ◽  
Thomas Christen ◽  
Jarrett Rosenberg ◽  
Zungho Zun ◽  
Michael E Moseley ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Relaxation Rates ◽  
Flow Mapping ◽  
Cerebrovascular Reserve ◽  
Lower Baseline ◽  
Kendall’S Τ ◽  
Free Induction ◽  
Measured Relaxation

This study aimed to determine whether measurements of cerebrovascular reserve and oxygenation, assessed with spin relaxation rate R2′, yield similar information about pathology in pre-operative Moyamoya disease patients, and to assess whether R2′ is a better measure of oxygenation than other proposed markers, such as R2* and R2. Twenty-five pre-operative Moyamoya disease patients were scanned at 3.0T with acetazolamide challenge. Cerebral blood flow mapping with multi-delay arterial spin labeling, and R2*, R2, and R2′ mapping with Gradient-Echo Sampling of Free Induction Decay and Echo were performed. No baseline cerebral blood flow difference was found between angiographically abnormal and normal regions (49 ± 12 vs. 48 ± 11 mL/100 g/min, p = 0.44). However, baseline R2′ differed between these regions (3.2 ± 0.7 vs. 2.9 ± 0.6 s−1, p < 0.001), indicating reduced oxygenation in abnormal regions. Cerebrovascular reserve was lower in angiographically abnormal regions (21 ± 38 vs. 41 ± 26%, p = 0.001). All regions showed trend toward significantly improved oxygenation post-acetazolamide. Regions with poorer cerebrovascular reserve had lower baseline oxygenation (Kendall's τ = −0.24, p = 0.003). A number of angiographically abnormal regions demonstrated preserved cerebrovascular reserve, likely due to the presence of collaterals. Finally, of the concurrently measured relaxation rates, R2′ was superior for oxygenation assessment.

scholarly journals Cerebral blood flow, transit time, and apparent diffusion coefficient in moyamoya disease before and after acetazolamide

2016 ◽  
Vol 59 (1) ◽  
pp. 5-12 ◽  
Author(s):  
Christian Federau ◽  
Soren Christensen ◽  
Zungho Zun ◽  
Sun-Won Park ◽  
Wendy Ni ◽  
...  
Keyword(s):  
Blood Flow ◽  
Diffusion Coefficient ◽  
Cerebral Blood Flow ◽  
Apparent Diffusion Coefficient ◽  
Transit Time ◽  
Moyamoya Disease ◽  
Before And After ◽  
Apparent Diffusion

Factors of Delayed Hyperperfusion and the Importance of Repeated Cerebral Blood Flow Evaluation for Hyperperfusion After Direct Bypass for Moyamoya Disease

2018 ◽  
Vol 118 ◽  
pp. e468-e472 ◽  
Author(s):  
Shunsuke Nomura ◽  
Koji Yamaguchi ◽  
Tatsuya Ishikawa ◽  
Akitsugu Kawashima ◽  
Yoshikazu Okada ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease ◽  
Direct Bypass ◽  
Blood Flow Evaluation

Cerebral blood flow findings in moyamoya disease in adults

2009 ◽  
Vol 85 (5) ◽  
pp. 318-322 ◽  
Author(s):  
E. Dietrichs ◽  
A. Dahl ◽  
R. Nyberg-Hansen ◽  
D. Russell ◽  
K. Rootwelt ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Moyamoya Disease
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