Epileptic encephalopathy with continuous spikes and waves in the occipito-temporal region during slow-wave sleep in two patients with acquired Kanji dysgraphia

2014 ◽  
Vol 16 (4) ◽  
pp. 540-545 ◽  
Author(s):  
Ichiro Kuki ◽  
Hisashi Kawawaki ◽  
Shin Okazaki ◽  
Hiroko Ikeda ◽  
Kiyotaka Tomiwa
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Nilika Shah Singhal ◽  
Joseph E. Sullivan

Continuous spike and wave during slow wave sleep (CSWS) is an epileptic encephalopathy that presents with neurocognitive regression and clinical seizures, and that demonstrates an electroencephalogram (EEG) pattern of electrical status epilepticus during sleep, as defined by the Commission on Classification and Terminology of the International League Against Epilepsy 1989. CSWS is an age-related condition, typically presenting in children around 5 years of age, with clinical seizures which progress within 2 years to a severe epileptic encephalopathy. The pathophysiology of CSWS is not completely understood, but the corticothalamic neuronal network involved in sleep patterns is thought to be involved. Genetic predisposition and injury in early development are thought to play etiological roles. Treatment strategies have involved traditional anticonvulsants, hormonal therapies, and other newer techniques. Outcomes are fair, and the thought is that earlier diagnosis and intervention preserve neurocognitive development, as in the case of other epileptic encephalopathies. Further understanding of the mechanisms of CSWS may lead to improved therapeutic options and thus outcomes of children with CSWS.


Seizure ◽  
2007 ◽  
Vol 16 (2) ◽  
pp. 190-192 ◽  
Author(s):  
Yasuhiko Kawakami ◽  
Yoshiaki Matsumoto ◽  
Kiyoshi Hashimoto ◽  
Kentaro Kuwabara ◽  
Kiyotaka Hirata ◽  
...  

1995 ◽  
Vol 10 (2) ◽  
pp. 127-133 ◽  
Author(s):  
Pertti J. Rintahaka ◽  
Harry T. Chugani ◽  
Raman Sankar

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S60-S61
Author(s):  
J. BORN ◽  
R. PIETROWSKY ◽  
P. PAUSCHINGER ◽  
H. L. FEHM

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