The association of epileptic focus estimated by magnetoencephalography with cognitive function in non-lesional epilepsy with continuous spikes and waves during slow wave sleep (ECSWS) children

2019 ◽  
Vol 41 (2) ◽  
pp. 163-172 ◽  
Author(s):  
Shinichi Magara ◽  
Takao Komatsubara ◽  
Moemi Hojo ◽  
Yu Kobayashi ◽  
Mihoko Yoshino ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Slow Wave ◽  
Slow Wave Sleep ◽  
Epileptic Focus ◽  
Continuous Spikes And Waves

scholarly journals Slow Wave Sleep and EEG Delta Spectral Power are Associated with Cognitive Function in Parkinson’s Disease

2020 ◽  
pp. 1-12
Author(s):  
Kimberly H. Wood ◽  
Adeel A. Memon ◽  
Raima A. Memon ◽  
Allen Joop ◽  
Jennifer Pilkington ◽  
...  
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Cognitive Performance ◽  
Slow Wave ◽  
Effect Size ◽  
Processing Speed ◽  
Slow Wave Sleep ◽  
Spectral Power ◽  
Z Scores ◽  
Domain Scores

Background: Cognitive and sleep dysfunction are common non-motor symptoms in Parkinson’s disease (PD). Objective: Determine the relationship between slow wave sleep (SWS) and cognitive performance in PD. Methods: Thirty-two PD participants were evaluated with polysomnography and a comprehensive level II neurocognitive battery, as defined by the Movement Disorders Society Task Force for diagnosis of PD-mild cognitive impairment. Raw scores for each test were transformed into z-scores using normative data. Z-scores were averaged to obtain domain scores, and domain scores were averaged to determine the Composite Cognitive Score (CCS), the primary outcome. Participants were grouped by percent of SWS into High SWS and Low SWS groups and compared on CCS and other outcomes using 2-sided t-tests or Mann-Whitney U. Correlations of cognitive outcomes with sleep architecture and EEG spectral power were performed. Results: Participants in the High SWS group demonstrated better global cognitive function (CCS) (p = 0.01, effect size: r = 0.45). In exploratory analyses, the High SWS group showed better performance in domains of executive function (effect size: Cohen’s d = 1.05), language (d = 0.95), and processing speed (d = 1.12). Percentage of SWS was correlated with global cognition and executive function, language, and processing speed. Frontal EEG delta power during N3 was correlated with the CCS and executive function. Cognition was not correlated with subjective sleep quality. Conclusion: Increased SWS and higher delta spectral power are associated with better cognitive performance in PD. This demonstrates the significant relationship between sleep and cognitive function and suggests that interventions to improve sleep might improve cognition in individuals with PD.

scholarly journals Treatment with flunitrazepam of continuous spikes and waves during slow wave sleep (CSWS) in children

Seizure ◽  
2007 ◽  
Vol 16 (2) ◽  
pp. 190-192 ◽  
Author(s):  
Yasuhiko Kawakami ◽  
Yoshiaki Matsumoto ◽  
Kiyoshi Hashimoto ◽  
Kentaro Kuwabara ◽  
Kiyotaka Hirata ◽  
...  
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Continuous Spikes And Waves

scholarly journals Acoustic slow wave sleep enhancement via a novel, automated device improves executive function in middle-aged men

SLEEP ◽  
2019 ◽  
Author(s):  
Charmaine Diep ◽  
Suzanne Ftouni ◽  
Jessica E Manousakis ◽  
Christian L Nicholas ◽  
Sean P A Drummond ◽  
...  
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Slow Wave ◽  
Slow Wave Sleep ◽  
Healthy Adult ◽  
Acoustic Stimulation ◽  
Trial Registration ◽  
Cognitive Capacity ◽  
Adult Males ◽  
Middle Aged

Abstract Study Objectives As slow-wave activity (SWA) is critical for cognition, SWA-enhancing technologies provide an exciting opportunity to improve cognitive function. We focus on improving cognitive function beyond sleep-dependent memory consolidation, using an automated device, and in middle-aged adults, who have depleted SWA yet a critical need for maximal cognitive capacity in work environments. Methods Twenty-four healthy adult males aged 35–48 years participated in a randomized, double-blind, cross-over study. Participants wore an automated acoustic stimulation device that monitored real-time sleep EEG. Following an adaptation night, participants were exposed to either acoustic tones delivered on the up phase of the slow-wave (STIM) or inaudible “tones” during equivalent periods of stimulation (SHAM). An executive function test battery was administered after the experimental night. Results STIM resulted in an increase in delta (0.5–4 Hz) activity across the full-night spectra, with enhancement being maximal at 1 Hz. SWA was higher for STIM relative to SHAM. Although no group differences were observed in any cognitive outcomes, due to large individual differences in SWA enhancement, higher SWA responders showed significantly improved verbal fluency and working memory compared with nonresponders. Significant positive associations were found between SWA enhancement and improvement in these executive function outcomes. Conclusions Our study suggests that (1) an automated acoustic device enhances SWA; (2) SWA enhancement improves executive function; (3) SWA enhancement in middle-aged men may be an important therapeutic target for enhancing cognitive function; and (4) there is a need to examine interindividual responses to acoustic stimulation and its effect on subsequent cognitive function. Clinical trial registration This study has been registered with the Australian New Zealand Clinical Trials Registry. “The efficacy of acoustic tones in slow-wave sleep enhancement and cognitive function in healthy adult males”. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=371548&isReview=true Registration ACTRN12617000399392.

Landau-Kleffner Syndrome With Continuous Spikes and Waves During Slow-Wave Sleep

1995 ◽  
Vol 10 (2) ◽  
pp. 127-133 ◽  
Author(s):  
Pertti J. Rintahaka ◽  
Harry T. Chugani ◽  
Raman Sankar
Keyword(s):  
Slow Wave ◽  
Slow Wave Sleep ◽  
Continuous Spikes And Waves
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