scholarly journals Randomized Trial of Plasma Exchange or High-Dosage Methylprednisolone as Adjunctive Therapy for Severe Renal Vasculitis

2007 ◽  
Vol 18 (7) ◽  
pp. 2180-2188 ◽  
Author(s):  
David R.W. Jayne ◽  
Gill Gaskin ◽  
Niels Rasmussen ◽  
Daniel Abramowicz ◽  
Franco Ferrario ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Plasma Exchange ◽  
Adjunctive Therapy ◽  
Renal Vasculitis

Therapeutic Plasma Exchange in Neonatal Septic Shock: A Retrospective Cohort Study

2019 ◽  
Vol 37 (09) ◽  
pp. 962-969
Author(s):  
Taylor Sawyer ◽  
Zeenia Billimoria ◽  
Sarah Handley ◽  
Kendra Smith ◽  
Larissa Yalon ◽  
...  
Keyword(s):  
Septic Shock ◽  
Cohort Study ◽  
Plasma Exchange ◽  
Retrospective Cohort Study ◽  
Adjunctive Therapy ◽  
Retrospective Cohort ◽  
Life Support ◽  
Therapeutic Plasma Exchange ◽  
Convenience Sample ◽  
Icu Discharge

Objective This study aimed to examine the use of therapeutic plasma exchange (TPE) as adjunctive therapy in neonatal septic shock. Study Design This retrospective cohort study was performed on a convenience sample of neonates in a quaternary children's hospital between January 2018 and February 2019. Results We identified three neonates with septic shock who received TPE. Two neonates had adenovirus sepsis, and one had group B streptococcal sepsis. All neonates were on extracorporeal life support (ECLS) when TPE was started. The median duration of TPE was 6 days (interquartile range [IQR]: 3–15), with a median of four cycles (IQR: 3–5). Lactate levels decreased significantly after TPE (median before TPE: 5.4 mmol/L [IQR: 2.4–6.1] vs. median after TPE: 1.2 mmol/L [IQR: 1.0–5.8]; p < 0.001). Platelet levels did not change (median before TPE: 73,000/mm3 [IQR: 49,000–100,000] vs. median after TPE: 80,000/mm3 (IQR: 62,000–108,000); p = 0.2). Organ failure indices improved after TPE in two of the three neonates. Hypocalcemia was seen in all cases despite prophylactic calcium infusions. One neonate died, and two survived to ICU discharge. Conclusion TPE can be safely performed in neonates with septic shock. TPE may have a role as an adjunctive therapy in neonates with septic shock requiring ECLS.

Influence of Plasma Exchange on Serum Levels of Cytokines and Adhesion Molecules in ANCA-Positive Renal Vasculitis

1998 ◽  
Vol 16 (2) ◽  
pp. 72-80 ◽  
Author(s):  
V. Tesař ◽  
E. Jelínková ◽  
Z. Mašek ◽  
M. Jirsa Jr. ◽  
J. Žabka ◽  
...  
Keyword(s):  
Plasma Exchange ◽  
Adhesion Molecules ◽  
Serum Levels ◽  
Renal Vasculitis

scholarly journals A Randomized Trial of Fixed-Dose Combination Brinzolamide 1%/Brimonidine 0.2% as Adjunctive Therapy to Travoprost 0.004%

2016 ◽  
Vol 165 ◽  
pp. 188-197 ◽  
Author(s):  
Robert M. Feldman ◽  
Gregory Katz ◽  
Matthew McMenemy ◽  
Douglas A. Hubatsch ◽  
Tony Realini
Keyword(s):  
Randomized Trial ◽  
Adjunctive Therapy ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Dose Combination
Sign in / Sign up

Export Citation Format

Share Document