Gene Expression Profile in Human Late Radiation Enteritis Obtained by High-Density cDNA Array Hybridization

2004 ◽  
Vol 161 (3) ◽  
pp. 299-311 ◽  
Author(s):  
Marie-Catherine Vozenin-Brotons ◽  
Fabien Milliat ◽  
Christine Linard ◽  
Carine Strup ◽  
Agnès François ◽  
...  
2000 ◽  
Vol 57 (4) ◽  
pp. 1452-1459 ◽  
Author(s):  
Naohiro Yano ◽  
Masayuki Endoh ◽  
Kimberly Fadden ◽  
Hiroshi Yamashita ◽  
Agnes Kane ◽  
...  

2007 ◽  
Vol 8 (2) ◽  
pp. 88-97 ◽  
Author(s):  
Qing-chao Jin ◽  
Hai-tao Dong ◽  
You-liang Peng ◽  
Bao-shan Chen ◽  
Jing Shao ◽  
...  

2000 ◽  
Vol 2 (3) ◽  
pp. 93-100 ◽  
Author(s):  
DEBORAH LYN ◽  
XIAOWEI LIU ◽  
NICOLE A. BENNETT ◽  
NERIMIAH L. EMMETT

Lyn, Deborah, Xiaowei Liu, Nicole A. Bennett, and Nerimiah L. Emmett. Gene expression profile in mouse myocardium after ischemia. Physiol Genomics 2: 93–100, 2000.—This study was designed to elaborate a molecular profile of expressed genes during ischemic injury to the mouse heart after surgical constriction of the left coronary artery without reperfusion. A mouse cDNA array containing 588 known genes was used to compare gene expression in heart RNA after 24-h ischemia with control tissue. Alterations in gene expression on the array were supported by relative reverse transcription-polymerase chain reaction analysis after timed periods of ischemia. Decreased levels of the cell cycle regulator p18ink4 and the oxidative responsive gene glutathione S-transferase were accompanied by an upregulation of the genes associated with cardiac muscle development, α-myosin heavy chain and fetal myosin alkali light chain. Other stress responses elicited by cardiac injury included an induction of Egr-1 and Egr-3 transcription factors, as well as the apoptotic regulator Bax. Altogether, these findings indicate that expression of genes associated with a fetal transcription program may be involved with the post ischemic remodeling process in heart ventricles.


2001 ◽  
Vol 9 (5) ◽  
pp. 360-370 ◽  
Author(s):  
Jana Cole ◽  
Raymond Tsou ◽  
Ken Wallace ◽  
Nicole Gibran ◽  
Frank Isik

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